EGFR Mutational Analysis Test
Short Name: EGFR Mutational Analysis
Also known as: EGFR Gene Mutation Test, EGFR Testing for Lung Cancer, EGFR Analysis
EGFR Mutational Analysis Test test available at DNA Labs India for ₹10,000. Uses PCR, Fragment Analysis, Sequencing on Formalin fixed paraffin embedded (FFPE) block containing tumor tissue samples. Results in Reports are available within 4-5 days after sample receipt, with sample collection on Mon/Thu by 9 am and reports by Fri/Tue.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect EGFR gene mutations in tumor tissue for diagnosing non-small cell lung cancer (NSCLC) and determining eligibility for targeted therapy.
- Test Code
- 510
- Price
- ₹10,000
- Sample Type
- Formalin fixed paraffin embedded (FFPE) block containing tumor tissue
- Result Time
- Reports are available within 4-5 days after sample receipt, with sample collection on Mon/Thu by 9 am and reports by Fri/Tue.
- Fasting Required
- No
- Method
- PCR, Fragment Analysis, Sequencing
Sample Collection
Provide a copy of the histopathology report. Ensure the FFPE block has at least 10% tumor cells. Fill NGS Test Requisition Form (Form 40) completely.
Method: Surgical biopsy or tissue biopsy
Laboratory Analysis
Sample collection is performed via biopsy or surgery; no special actions needed from patient during collection.
Report Delivery
Ship the FFPE block at room temperature. Retain a copy of the histopathology report for reference.
Timeline: Reports are available within 4-5 days after sample receipt, with sample collection on Mon/Thu by 9 am and reports by Fri/Tue.
Patient Instructions
About This Test
Who Should Get This Test
To detect EGFR gene mutations in tumor tissue for diagnosing non-small cell lung cancer (NSCLC) and determining eligibility for targeted therapy.
How to Prepare
- Submit formalin fixed paraffin embedded (FFPE) block containing tumor tissue
- Ensure the block contains minimum 10% tumor cells
- Ship at room temperature
- Include a copy of the histopathology report
- Duly filled NGS Test Requisition Form (Form 40) is mandatory
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"EGFR Mutational Analysis is essential for identifying patients with non-small cell lung cancer (NSCLC) who may benefit from targeted therapies, improving treatment outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient tumor cells (<10%) in FFPE block
- Missing or incomplete histopathology report
- Incorrect sample type (e.g., blood, fresh tissue without fixation)
- Damaged or degraded FFPE block
Understanding Your Results
Detected
EGFR mutation present; patient may be eligible for targeted therapy drugs like tyrosine kinase inhibitors.
Not Detected
No EGFR mutation found; alternative treatments such as chemotherapy or immunotherapy may be considered.
Specific mutation identified
Provides details for selecting appropriate targeted therapy based on mutation type.
Consult an oncologist immediately if symptoms of lung cancer persist, before starting treatment, or to interpret test results for therapy planning.
Limitations
- ⚠May not detect all rare EGFR mutations
- ⚠Requires sufficient tumor content; minimum 10% tumor cells
- ⚠Results are specific to the tissue sample provided
- ⚠Does not assess other genetic alterations beyond EGFR
Risks & Considerations
- ●Biopsy procedure risks (e.g., infection, bleeding) are associated with sample collection, not the test itself
- ●No direct risks from the genetic analysis
Interfering Factors
- ●Inadequate tumor tissue in sample (<10% tumor cells)
- ●DNA degradation due to improper sample handling
- ●Contamination from non-tumor cells
- ●Use of incorrect fixation methods
Compare With Similar Tests
| Test | EGFR Mutational Analysis Test | ALK Mutation Test | KRAS Mutation Test |
|---|---|---|---|
| Comparison | EGFR Mutational Analysis Test | Detects ALK gene rearrangements in lung cancer; often tested alongside EGFR for comprehensive profiling. | Identifies KRAS mutations common in lung and colorectal cancers; different therapeutic implications. |
Frequently Asked Questions
What is EGFR?
Why is the EGFR Mutational Analysis Test done?
What are the symptoms of lung cancer that may require this test?
How is the test performed?
What is the cost of the EGFR Mutational Analysis Test in India?
Is home sample collection available for this test?
How should I prepare for the test?
What does a positive result mean?
What if the test is negative?
Is the test covered by insurance?
What is the turnaround time for results?
Are there any risks associated with this test?
Related Tests
B-Cell Rearrangement Detection Test
₹22,000Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test
₹20,000Epstein-Barr Virus Early RNA (EBER-ISH) In-Situ-Hybridization Test
₹6,000OncoPro NCCN Lung Cancer Panel with PD-L1 Test
₹140,400Acute Myeloid Leukemia (AML) Cytogenetics Panel Test
₹23,000AML ETO t(8;21) Gene Rearrangement PCR Qualitative Test
₹6,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.