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DNA Labs India

Extractable Nuclear Antigens (ENA) / Anti Nuclear Antibodies (ANA) Quantitative Profile Test

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Extractable Nuclear Antigens (ENA) / Anti Nuclear Antibodies (ANA) Quantitative Profile Test

Short Name: ENA/ANA Quantitative Profile Test

Also known as: ENA Antibody Test, ANA Profile Test

Extractable Nuclear Antigens (ENA) / Anti Nuclear Antibodies (ANA) Quantitative Profile Test test available at DNA Labs India for ₹10,000. Uses Enzyme Immunoassay on Serum samples. Results in Reports are available same day if the sample is received by 9 am on Tuesday or Friday.. Free home collection in 300+ cities across India.

SerologyAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the ENA/ANA Quantitative Profile Test is to detect and quantify specific antibodies that target extractable nuclear antigens and anti-nuclear antigens. These antibodies are indicative of autoimmune activity. The test measures individual antibodies to Sm, U1RNP, SS-A/Ro, SS-B/La, Jo-1, Scl-70, and Centromere antigens. By identifying these antibodies, the test aids in diagnosing various autoimmune disorders, assessing disease severity, and monitoring treatment response.

Test Code
536
Price
₹10,000
Sample Type
Serum
Result Time
Reports are available same day if the sample is received by 9 am on Tuesday or Friday.
Fasting Required
No
Method
Enzyme Immunoassay
Step 1

Sample Collection

No special preparation required. However, inform your doctor about any medications you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will draw blood from a vein in your arm using a needle. The process takes only a few minutes.

Step 3

Report Delivery

Apply pressure to the site with a bandage. Mild bruising may occur.

Timeline: Reports are available same day if the sample is received by 9 am on Tuesday or Friday.

Patient Instructions

1
Before the Test:No fasting required. You may eat and drink normally before the test.
2
During the Test:The test involves a simple blood draw from a vein in your arm.
3
After the Test:You can resume normal activities immediately after the test.

About This Test

Who Should Get This Test

The purpose of the ENA/ANA Quantitative Profile Test is to detect and quantify specific antibodies that target extractable nuclear antigens and anti-nuclear antigens. These antibodies are indicative of autoimmune activity. The test measures individual antibodies to Sm, U1RNP, SS-A/Ro, SS-B/La, Jo-1, Scl-70, and Centromere antigens. By identifying these antibodies, the test aids in diagnosing various autoimmune disorders, assessing disease severity, and monitoring treatment response.

How to Prepare

  • Blood sample should be collected in a Serum Separator Tube (SST)
  • Ship sample refrigerated or frozen to maintain stability

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This quantitative profile test helps in precise diagnosis and monitoring of autoimmune conditions. Early detection can lead to better management. Consult a rheumatologist for personalized advice."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume3 mL (1.5 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature6 hours
Refrigerator1 week
Frozen4 weeks

Understanding Your Results

Results of the ENA/ANA Quantitative Profile Test are interpreted based on the presence or absence of specific antibodies. A positive result for one or more antibodies may indicate an autoimmune disorder, but clinical correlation is necessary for accurate diagnosis.
📊

Highly specific for systemic lupus erythematosus (SLE)

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Associated with mixed connective tissue disease (MCTD) and SLE

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Linked to Sjogren's syndrome and SLE, can be associated with neonatal lupus

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Often found with Anti-SS-A/Ro in Sjogren's syndrome

📊

Indicative of polymyositis or dermatomyositis

📊

Specific for systemic sclerosis (scleroderma)

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Associated with limited cutaneous systemic sclerosis and CREST syndrome

⚠️ When to Consult a Doctor:

If your test results are positive or if you experience persistent symptoms of autoimmune disorders, consult your doctor or a rheumatologist for further evaluation and management.

Risks & Considerations

  • ●Mild pain or bruising at the blood draw site
  • ●In rare cases, infection or dizziness

Frequently Asked Questions

What is the ENA/ANA Quantitative Profile Test?
It is a blood test that measures specific antibodies to extractable nuclear antigens and anti-nuclear antigens, helping diagnose autoimmune disorders.
Why is this test recommended?
This test is recommended if you have symptoms of autoimmune disorders like fatigue, joint pain, or skin rashes, to aid in diagnosis and monitoring.
How is the test performed?
A blood sample is drawn from a vein in your arm and analyzed using enzyme immunoassay to detect and quantify antibodies.
Is fasting required for this test?
No, fasting is not required. You can eat and drink normally before the test.
What are the normal values for this test?
Normal results typically show negative for all antibodies, indicating no significant autoimmune activity.
What do abnormal results indicate?
Abnormal results, with positive antibodies, may suggest an autoimmune disorder such as lupus, scleroderma, or Sjogren's syndrome, but require clinical correlation.
How long does it take to get the results?
Results are available the same day if the sample is received by 9 am on Tuesday or Friday.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What is the cost of the test?
The test costs INR 10,000, which includes the test and a doctor consultation.
Can this test diagnose all autoimmune disorders?
No, this test measures specific antibodies and helps diagnose certain autoimmune disorders, but not all; it should be used alongside clinical evaluation.
Are there any risks associated with the test?
The risks are minimal, such as mild pain or bruising at the blood draw site, with rare chances of infection or dizziness.
How should I prepare for the test?
No special preparation is required. Inform your doctor about any medications you are taking before the test.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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