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FISH - 1p & 19q Codeletion Test

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FISH - 1p & 19q Codeletion Test

Short Name: FISH 1p/19q

Also known as: 1p/19q Codeletion Test, Fluorescence In Situ Hybridization for 1p and 19q

FISH - 1p & 19q Codeletion Test test available at DNA Labs India for ₹12,000. Uses FISH on Formalin fixed paraffin embedded tissue block samples. Results in 1 week. Free home collection in 300+ cities across India.

FISHAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the FISH 1p & 19q Codeletion Test is to identify genetic abnormalities associated with oligodendroglioma, aiding in accurate diagnosis, prognosis assessment, and treatment planning. It helps determine if a patient's tumor is likely to respond to chemotherapy, thereby personalizing care and improving survival chances.

Test Code
560
Price
₹12,000
Sample Type
Formalin fixed paraffin embedded tissue block
Result Time
1 week
Fasting Required
No
Method
FISH
Step 1

Sample Collection

Inform your doctor about any medications or medical conditions. Ensure tissue sample is collected via biopsy or surgery as directed.

Method: Biopsy or Surgery

Step 2

Laboratory Analysis

Tissue sample is fixed in formalin and embedded in paraffin block, with mandatory requisition form (Form 17).

Step 3

Report Delivery

Sample is shipped at room temperature to the laboratory for FISH analysis. Results are available in approximately one week.

Timeline: 1 week

Patient Instructions

1
Before the Test:Consult your doctor for referral. Ensure tissue sample is collected and requisition form is filled.
2
During the Test:Test is performed in a laboratory on the provided tissue sample using FISH technology.
3
After the Test:Discuss results with your doctor to determine treatment options. Results are typically available in one week.

About This Test

Who Should Get This Test

The purpose of the FISH 1p & 19q Codeletion Test is to identify genetic abnormalities associated with oligodendroglioma, aiding in accurate diagnosis, prognosis assessment, and treatment planning. It helps determine if a patient's tumor is likely to respond to chemotherapy, thereby personalizing care and improving survival chances.

How to Prepare

  • Submit formalin fixed paraffin embedded tissue block.
  • Tissue block must contain 10% tumor tissue.
  • Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for personalized treatment in oligodendroglioma cases, helping to predict chemotherapy response and survival outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded tissue block
ContainerFFPE Tissue Block
Collection MethodBiopsy or Surgery

Sample Stability

Room temperature during shipping
Sample Rejection Criteria:
  • Insufficient tumor tissue
  • Missing or incomplete requisition form
  • Improperly fixed tissue

Understanding Your Results

Results indicate the presence or absence of 1p and 19q codeletion, which is key for diagnosing oligodendroglioma and predicting treatment response.
Positive for codeletion: Associated with oligodendroglioma and favorable response to chemotherapy.
Negative for codeletion: May indicate other tumor types or require further testing.
Consult with an oncologist to understand implications for treatment.
⚠️ When to Consult a Doctor:

If you experience symptoms like persistent headaches, seizures, or neurological changes, or if you have a brain tumor diagnosis, consult an oncologist or neurologist for test evaluation.

Limitations

  • Test is specific to oligodendroglioma and may not apply to other brain tumors
  • Requires adequate tumor tissue for accurate analysis

Risks & Considerations

  • No direct risks to the patient; test is performed on tissue sample.

Interfering Factors

  • Poor tissue quality
  • Insufficient tumor content in sample

Frequently Asked Questions

What is the FISH 1p & 19q Codeletion Test?
It is a genetic test using fluorescent probes to detect deletions on chromosomes 1 and 19 in brain tumor tissues, helping diagnose oligodendroglioma.
Why is this test performed?
To identify specific genetic abnormalities for accurate diagnosis, prognosis, and personalized treatment planning in brain tumors.
What are the symptoms of oligodendroglioma?
Common symptoms include headaches, seizures, nausea, vomiting, changes in vision or hearing, and personality changes.
How is the test performed?
The test is performed on a formalin-fixed paraffin-embedded tissue block from biopsy or surgery, analyzed in a lab using FISH technology.
What is the cost of the FISH 1p & 19q Codeletion Test?
The cost is INR 12000, which includes home sample collection in many cities across India.
How long does it take to get results?
Results are typically available within one week after sample submission.
Is home sample collection available?
Yes, free home collection is offered for online bookings across numerous cities in India.
What sample is required for the test?
A formalin fixed paraffin embedded tissue block with at least 10% tumor tissue is required.
What does a positive result mean?
A positive result indicates the presence of 1p and 19q codeletion, associated with oligodendroglioma and better response to chemotherapy.
What does a negative result mean?
A negative result suggests no codeletion, which may indicate other tumor types or need for further diagnostic tests.
Is the test covered by insurance?
Coverage depends on your insurance plan; it is not typically covered under government schemes like PMJAY or CGHS without prior approval.
How to prepare for the test?
No special preparation is needed, but ensure the tissue sample is collected properly and the requisition form is submitted.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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