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FISH - CLL Panel Test

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FISH - CLL Panel Test

Also known as: Fluorescence In Situ Hybridization - CLL Panel, FISH for CLL

FISH - CLL Panel Test test available at DNA Labs India for ₹12,000. Uses FISH on Whole Blood or Bone Marrow samples. Results in 4 working days. Free home collection in 300+ cities across India.

FISHAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To detect specific genetic abnormalities in CLL, including deletions at 11q23 (ATM gene), 17p13.1 (TP53 gene), 13q14.3, 13q34, trisomy 12, and IGH gene rearrangements.

Test Code
571
Price
₹12,000
Sample Type
Whole Blood or Bone Marrow
Result Time
4 working days
Fasting Required
No
Method
FISH
Step 1

Sample Collection

Ensure the Chromosome & FISH analysis Requisition Form (Form 17) is duly filled and signed by the referring physician.

Method: Venipuncture or Bone Marrow Aspiration

Step 2

Laboratory Analysis

Sample collection by a trained phlebotomist using sterile techniques to avoid contamination.

Step 3

Report Delivery

Ship the sample at 18-22°C; do not freeze. Ensure timely transport to the lab within 48 hours.

Timeline: 4 working days

Patient Instructions

1
Before the Test:Consult with an oncologist to determine test necessity and complete all required forms.
2
During the Test:A blood draw or bone marrow aspiration will be performed; minimal discomfort expected.
3
After the Test:Results available in 4 working days; discuss findings with your doctor for next steps.

About This Test

Who Should Get This Test

To detect specific genetic abnormalities in CLL, including deletions at 11q23 (ATM gene), 17p13.1 (TP53 gene), 13q14.3, 13q34, trisomy 12, and IGH gene rearrangements.

How to Prepare

  • Complete the mandatory Form 17 before sample collection
  • Collect 5 mL of whole blood or 4 mL of bone marrow in two Green Top (Sodium Heparin) tubes
  • Maintain sample at room temperature (18-22°C) during shipping; do not freeze

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The FISH - CLL Panel Test is essential for identifying specific genetic markers in CLL, which guide prognosis and targeted therapy decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood or Bone Marrow
Sample Volume5 mL whole blood or 4 mL bone marrow
ContainerGreen Top (Sodium Heparin) tubes
Collection MethodVenipuncture or Bone Marrow Aspiration

Sample Stability

Room Temperature: 48 hours
Refrigerated: Not applicable
Frozen: Not applicable
Sample Rejection Criteria:
  • Incomplete or missing Form 17
  • Frozen or improperly stored samples
  • Insufficient sample volume

Understanding Your Results

Results indicate the presence or absence of specific genetic abnormalities associated with CLL. Abnormal findings require correlation with clinical context.
📊

Presence of genetic deletions or trisomy

Suggests CLL with specific genetic profile, may influence prognosis and treatment

📊

Negative for all markers

No detectable genetic abnormalities by FISH; does not rule out CLL completely, further evaluation may be needed

⚠️ When to Consult a Doctor:

If you experience symptoms of CLL such as persistent fatigue, swollen lymph nodes, or unexplained weight loss, or if test results are abnormal, consult an oncologist or hematologist promptly.

Limitations

  • ⚠Limited to specific genetic markers; may not detect all CLL abnormalities
  • ⚠Requires fresh or properly preserved samples in Sodium Heparin tubes
  • ⚠Results should be interpreted in conjunction with clinical findings and other tests

Risks & Considerations

  • ●Pain or bruising at the sample collection site
  • ●Rare risk of infection or bleeding from bone marrow aspiration
  • ●Minimal discomfort during venipuncture

Interfering Factors

  • ●Poor sample quality or hemolysis
  • ●Incorrect sample handling or storage
  • ●Contamination during collection or transport

Compare With Similar Tests

TestFISH - CLL Panel TestFlow CytometryBone Marrow BiopsyComplete Blood Count (CBC)Cytogenetic Analysis
ComparisonFISH - CLL Panel TestUsed for immunophenotyping; FISH provides genetic detailsAssesses bone marrow involvement; FISH detects specific genetic abnormalitiesInitial screening for lymphocytosis; FISH confirms genetic basisBroad chromosome analysis; FISH is targeted for specific loci

Frequently Asked Questions

What is the FISH - CLL Panel Test?
It is a genetic test using Fluorescence In Situ Hybridization (FISH) to detect specific chromosomal abnormalities in Chronic Lymphocytic Leukemia (CLL).
How much does the FISH - CLL Panel Test cost in India?
The test costs INR 12,000, with free home sample collection available across many cities.
What are the symptoms of CLL that may require this test?
Symptoms include swollen lymph nodes, fatigue, fever, night sweats, weight loss, and frequent infections.
How is the FISH - CLL Panel Test performed?
The test analyzes blood or bone marrow samples using FISH technology to identify genetic markers like deletions and trisomy.
What samples are needed for this test?
5 mL of whole blood or 4 mL of bone marrow collected in Sodium Heparin tubes.
Is fasting required before the FISH - CLL Panel Test?
No, fasting is not required, but completing the mandatory Form 17 is essential.
How long does it take to get the results?
Results are typically available within 4 working days after sample collection.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home collection for online bookings in numerous cities across India.
What do abnormal results from the FISH - CLL Panel Test mean?
Abnormal results indicate genetic abnormalities associated with CLL, which help in diagnosis and treatment planning.
Can this test diagnose other types of cancer?
No, it is specifically designed for Chronic Lymphocytic Leukemia (CLL); other tests may be needed for different cancers.
Is the FISH - CLL Panel Test covered by insurance?
Coverage depends on your insurance plan; check with your provider for details.
Where can I get the FISH - CLL Panel Test done?
You can book the test through DNA Labs India, with services available in major cities like Mumbai, Delhi, Bangalore, and more.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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