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DNA Labs India

FISH - NTRK 1, 2 & 3 Gene Panel Test

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FISH - NTRK 1, 2 & 3 Gene Panel Test

FISH - NTRK 1, 2 & 3 Gene Panel Test test available at DNA Labs India for ₹17,550. Uses FISH (Fluorescence in situ Hybridization) on Formalin fixed paraffin embedded tissue block or three 4 micron sections on Poly L Lysine coated slides samples. Results in Report delivered in 4 working days. Free home collection in 300+ cities across India.

Oncologist🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect NTRK1, NTRK2, and NTRK3 gene rearrangements in cancer cells using FISH, aiding in the diagnosis of rare cancers and guiding targeted therapy decisions.

Test Code
614
Price
₹17,550
Sample Type
Formalin fixed paraffin embedded tissue block or three 4 micron sections on Poly L Lysine coated slides
Result Time
Report delivered in 4 working days
Fasting Required
No
Method
FISH (Fluorescence in situ Hybridization)
Step 1

Sample Collection

Complete the Genomics Clinical Information Requisition Form (Form 20) and ensure biopsy sample is properly preserved in formalin.

Method: Biopsy

Step 2

Laboratory Analysis

Biopsy procedure performed by a healthcare professional; sample collected as tissue block or slides.

Step 3

Report Delivery

Ship sample at room temperature to DNA Labs India; no specific storage requirements.

Timeline: Report delivered in 4 working days

Patient Instructions

1
Before the Test:No fasting required; ensure biopsy sample is collected and requisition form is completed.
2
During the Test:Biopsy procedure; sample sent to lab for FISH analysis using fluorescent probes.
3
After the Test:Sample processed; results available after 4 working days via online portal or other delivery methods.

About This Test

Who Should Get This Test

To detect NTRK1, NTRK2, and NTRK3 gene rearrangements in cancer cells using FISH, aiding in the diagnosis of rare cancers and guiding targeted therapy decisions.

How to Prepare

  • Submit formalin fixed paraffin embedded tissue block or three 4 micron sections on Poly L Lysine coated slides.
  • Ship sample at room temperature.
  • Include the duly filled Genomics Clinical Information Requisition Form (Form 20).
  • Ensure sample is labeled correctly with patient details.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early detection of NTRK gene fusions through FISH testing can guide targeted therapy with TRK inhibitors like Larotrectinib or Entrectinib, improving outcomes in rare cancer cases."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded tissue block or three 4 micron sections on Poly L Lysine coated slides
ContainerTissue block or slides
Collection MethodBiopsy

Understanding Your Results

Results indicate the presence or absence of NTRK gene rearrangements, which are critical for cancer diagnosis and treatment planning.
📊

Positive for any NTRK rearrangement

Gene fusion detected; suggests eligibility for targeted TRK inhibitor therapy.

📊

Negative for all NTRK rearrangements

No gene fusion detected; may require alternative diagnostic tests or therapies.

⚠️ When to Consult a Doctor:

Consult an oncologist immediately if symptoms persist, test results are positive, or for personalized treatment options based on genetic findings.

Risks & Considerations

  • ●Minor bleeding or infection at biopsy site
  • ●Rare allergic reaction to local anesthesia

Compare With Similar Tests

TestFISH - NTRK 1, 2 & 3 Gene Panel TestFISH - ALK Gene TestFISH - ROS1 Gene TestNext-Generation Sequencing (NGS) PanelImmunohistochemistry (IHC) for NTRK
ComparisonFISH - NTRK 1, 2 & 3 Gene Panel Test

Frequently Asked Questions

What is the FISH-NTRK 1,2,3 Gene Panel Test?
It is a genetic test using FISH to detect NTRK1, NTRK2, and NTRK3 gene rearrangements in cancer cells, helping diagnose rare cancers and guide targeted therapy.
What is the cost of this test at DNA Labs India?
The cost is INR 17550, with free home sample collection available in many Indian cities.
What symptoms might indicate the need for this test?
Symptoms include unexplained weight loss, fatigue, persistent pain, changes in skin, bowel or bladder habits, difficulty swallowing, or persistent cough, which could be associated with cancer.
How is cancer diagnosed using this test?
It is part of a comprehensive diagnosis involving biopsy samples, where FISH identifies genetic mutations linked to cancer, complementing other tests like imaging or blood tests.
What sample is required for the test?
Submit formalin fixed paraffin embedded tissue block or three 4 micron sections on Poly L Lysine coated slides, along with a completed requisition form.
Is fasting required before the test?
No, fasting is not required as it involves a biopsy sample.
How long does it take to get results?
Results are typically available within 4 working days after sample receipt.
What do positive results mean?
Positive results indicate NTRK gene fusions, which may make the patient eligible for targeted therapies like TRK inhibitors.
Are there any risks associated with the test?
Risks are minimal and related to the biopsy procedure, such as minor bleeding or infection at the site.
Can this test be done for any type of cancer?
It is specifically for cancers where NTRK fusions are suspected, especially rare tumors, as advised by an oncologist.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
How does this test compare to other genetic tests?
Unlike broad NGS panels, this FISH test specifically targets NTRK genes, providing focused detection for diagnosis and therapy guidance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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