FLT3 (ITD, D835Y) Mutation Detection Test
Short Name: FLT3 Mutation Detection
Also known as: FLT3-ITD, FLT3-D835Y, FLT3 Mutation Test
FLT3 (ITD, D835Y) Mutation Detection Test test available at DNA Labs India for ₹6,000. Uses End Point PCR on Bone marrow / Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of FLT3 mutation detection is to identify genetic mutations in the FLT3 gene that are associated with acute myeloid leukemia (AML). This test helps in diagnosing AML, determining prognosis, and guiding treatment decisions, especially for targeted therapies.
- Test Code
- 3016
- Price
- ₹6,000
- Sample Type
- Bone marrow / Peripheral blood
- Result Time
- 3-4 days
- Fasting Required
- No
- Method
- End Point PCR
Sample Collection
No special preparation required. Inform the doctor about any medications or recent treatments.
Method: Bone Marrow Aspiration or Venipuncture
Laboratory Analysis
A sample of bone marrow or peripheral blood will be collected by a trained phlebotomist or hematologist.
Report Delivery
Apply pressure to the collection site to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: 3-4 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of FLT3 mutation detection is to identify genetic mutations in the FLT3 gene that are associated with acute myeloid leukemia (AML). This test helps in diagnosing AML, determining prognosis, and guiding treatment decisions, especially for targeted therapies.
How to Prepare
- Use EDTA vacutainer for blood samples
- Transport bone marrow samples immediately to the lab
- Label samples correctly with patient details
- Avoid hemolysis during collection
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"FLT3 mutation detection is essential for risk stratification and targeted therapy in acute myeloid leukemia. Early identification can improve treatment outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect sample container
- Insufficient sample volume
- Improper labeling
Understanding Your Results
FLT3-ITD Detected
Presence of internal tandem duplication in FLT3 gene, associated with poor prognosis in AML.
FLT3-D835Y Detected
Presence of D835Y point mutation in FLT3 gene, associated with poor prognosis in AML.
Both Mutations Not Detected
No FLT3 mutations detected, which may indicate a better prognosis, but other factors should be considered.
Consult a hematologist or oncologist immediately if FLT3 mutations are detected for personalized treatment planning. Also, consult if symptoms of AML persist despite negative results.
Limitations
- ⚠May not detect all FLT3 mutations
- ⚠False negatives possible in low tumor burden
- ⚠Does not replace comprehensive AML genetic panel
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Pain or bruising at the blood draw site
- ●Infection risk for bone marrow aspiration
- ●Rare allergic reactions to antiseptics
Interfering Factors
- ●Sample contamination
- ●Improper sample storage or transport
- ●Hemolyzed or clotted samples
- ●Recent blood transfusion may affect results
Compare With Similar Tests
| Test | FLT3 (ITD, D835Y) Mutation Detection | NPM1 Mutation Detection | CEBPA Mutation Detection | RUNX1 Mutation Detection |
|---|---|---|---|---|
| Comparison | FLT3 (ITD, D835Y) Mutation Detection | NPM1 mutations are common in AML and often co-occur with FLT3 mutations. Combined testing provides better prognostic information. | CEBPA mutations are associated with a favorable prognosis in AML, unlike FLT3 mutations. | RUNX1 mutations indicate poor prognosis and may guide treatment decisions similar to FLT3. |
Frequently Asked Questions
What is FLT3 mutation detection?
Why is FLT3 mutation testing important for AML?
What are the symptoms of FLT3 mutations?
How is the FLT3 test performed?
What is the cost of FLT3 mutation detection in India?
Is home sample collection available for this test?
How long does it take to get FLT3 test results?
What does a positive FLT3 mutation result mean?
Can FLT3 mutations be treated?
Are there any risks associated with the test?
Do I need a doctor's prescription for this test?
How accurate is the FLT3 mutation detection test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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