Her-2 Neu DNA Detection & Quantification (RNA Detection) Qualitative Test
Short Name: Her-2 Neu Qualitative
Also known as: HER2/neu amplification test, HER2 FISH, HER2 IHC
Her-2 Neu DNA Detection & Quantification (RNA Detection) Qualitative Test test available at DNA Labs India for ₹11,560. Uses Real Time PCR on Whole Blood, Frozen And Formalin Fixed, Paraffin embedded. Benignant tissue samples. Results in Reports are delivered within 3 working days. Email reports within 36 hours, phone reports within 24 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the HER2 Neu DNA Detection & Quantification test is to determine whether a patient's tumor overexpresses the HER2 gene. This information is essential for: 1) Diagnosing HER2-positive breast cancer, 2) Predicting response to HER2-targeted therapies, 3) Assessing prognosis, 4) Guiding treatment planning, 5) Monitoring disease progression or recurrence. The test is recommended for all newly diagnosed invasive breast cancer patients and for those with metastatic disease to determine eligibility for targeted therapy.
- Test Code
- 6154
- CPT Code
- 88342
- ICD Code
- C50.9
- Price
- ₹11,560
- Sample Type
- Whole Blood, Frozen And Formalin Fixed, Paraffin embedded. Benignant tissue
- Result Time
- Reports are delivered within 3 working days. Email reports within 36 hours, phone reports within 24 hours.
- Fasting Required
- No
- Method
- Real Time PCR
Sample Collection
No special preparation required. However, patients must sign a consent document and bring any relevant clinical history.
Method: Venipuncture or biopsy
Laboratory Analysis
Blood sample collection is a routine procedure. For tissue biopsy, the procedure is performed by a healthcare professional.
Report Delivery
No specific aftercare required. Patients can resume normal activities immediately.
Timeline: Reports are delivered within 3 working days. Email reports within 36 hours, phone reports within 24 hours.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the HER2 Neu DNA Detection & Quantification test is to determine whether a patient's tumor overexpresses the HER2 gene. This information is essential for: 1) Diagnosing HER2-positive breast cancer, 2) Predicting response to HER2-targeted therapies, 3) Assessing prognosis, 4) Guiding treatment planning, 5) Monitoring disease progression or recurrence. The test is recommended for all newly diagnosed invasive breast cancer patients and for those with metastatic disease to determine eligibility for targeted therapy.
How to Prepare
- Sign the consent document before sample collection
- Provide clinical history of the patient
- For blood sample: Use EDTA tube, ensure proper mixing
- For tissue sample: Formalin-fixed paraffin-embedded (FFPE) block or frozen tissue
- Label the sample clearly with patient details
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"HER2 testing is essential for guiding targeted therapy in breast cancer. This qualitative test helps determine HER2 gene amplification status, which is critical for treatment decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood sample
- Clotted blood sample
- Insufficient tissue sample
- Incorrect labeling
- Sample not stored properly
Understanding Your Results
Positive
HER2 gene amplification detected. Tumor is HER2-positive. Targeted therapy (e.g., trastuzumab) may be recommended.
Negative
No HER2 gene amplification detected. Tumor is HER2-negative. Targeted therapy is unlikely to be effective.
Equivocal
Borderline result. Further testing (e.g., FISH) may be required to confirm HER2 status.
Consult your oncologist if you have been diagnosed with breast cancer or if you experience symptoms such as a new breast lump, skin changes, or unexplained weight loss. Your doctor will determine if HER2 testing is appropriate for you.
Limitations
- ⚠Qualitative test does not provide quantitative copy number
- ⚠May not detect low-level amplification
- ⚠Results should be interpreted in conjunction with clinical and histopathological findings
- ⚠Not a screening test for cancer
Risks & Considerations
- ●Minimal risk of bleeding or bruising at the blood draw site
- ●Rare risk of infection at the biopsy site
- ●No radiation exposure
Interfering Factors
- ●Improper sample handling or storage
- ●Contamination during collection
- ●Delay in processing
- ●Inadequate tissue sample (for biopsy)
- ●Presence of necrotic tissue
Compare With Similar Tests
| Test | Her-2 Neu DNA Detection & Quantification (RNA Detection) Qualitative Test | |||
|---|---|---|---|---|
| Comparison | Her-2 Neu DNA Detection & Quantification (RNA Detection) Qualitative Test |
Frequently Asked Questions
What is the cost of the HER2 Neu DNA Detection & Quantification test?
What is the purpose of this test?
What sample is required for this test?
Do I need to fast before the test?
How long does it take to get results?
Is home sample collection available?
What does a positive HER2 result mean?
What does a negative HER2 result mean?
Can this test be used for screening?
Is this test covered by insurance?
Are there any risks associated with the test?
How should I prepare for the test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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