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HLA - B27 Qualitative PCR Test

DNA Labs India | ISO 9001:2015 Certified

HLA - B27 Qualitative PCR Test

Short Name: HLA-B27 Qualitative PCR

Also known as: HLA-B27 Gene Test, HLA-B27 DNA Test

HLA - B27 Qualitative PCR Test test available at DNA Labs India for ₹4,500. Uses Real Time PCR on Whole Blood samples. Results in 10-12 days. Free home collection in 300+ cities across India.

Qualitative PCR🏠 Home Collection

✍️ Written By

Overview

The purpose of the HLA-B27 Qualitative PCR test is to identify the genetic marker HLA-B27, which is strongly associated with autoimmune diseases. This aids in the diagnosis and management of conditions like ankylosing spondylitis and reactive arthritis, guiding treatment decisions and monitoring disease progression.

Test Code
778
Price
₹4,500
Sample Type
Whole Blood
Result Time
10-12 days
Fasting Required
No
Method
Real Time PCR
Step 1

Sample Collection

No special preparation required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to stop bleeding.

Timeline: 10-12 days

Patient Instructions

1
Before the Test:No fasting or special preparation is required.
2
During the Test:A healthcare professional will collect a blood sample via venipuncture from your arm.
3
After the Test:Results will be available in 10-12 days via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

The purpose of the HLA-B27 Qualitative PCR test is to identify the genetic marker HLA-B27, which is strongly associated with autoimmune diseases. This aids in the diagnosis and management of conditions like ankylosing spondylitis and reactive arthritis, guiding treatment decisions and monitoring disease progression.

How to Prepare

  • Collect 3 mL whole blood in an EDTA (lavender top) tube
  • Ship refrigerated, do not freeze

Doctor's Notes

"The HLA-B27 test is crucial for diagnosing autoimmune conditions like ankylosing spondylitis. Early detection allows for timely management and improved patient outcomes."

Test Parameters & Specifications

Sample TypeWhole Blood
Sample Volume3 mL (minimum 2 mL)
ContainerLavender Top (EDTA) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerated: 72 hours
Frozen: Not applicable
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Incorrect tube type
  • Insufficient sample volume

Understanding Your Results

Results are reported as qualitative: HLA-B27 detected or not detected.
📊

Positive (Detected)

HLA-B27 gene is present, which is associated with a higher risk of autoimmune diseases such as ankylosing spondylitis. Clinical correlation is recommended.

📊

Negative (Not Detected)

HLA-B27 gene is not detected, indicating a lower risk for HLA-B27 associated conditions, but does not completely rule out autoimmune diseases.

⚠️ When to Consult a Doctor:

Consult a rheumatologist or immunologist if you have symptoms of autoimmune diseases or receive a positive test result for further evaluation and management.

Limitations

  • ⚠Positive result indicates increased risk but does not confirm disease
  • ⚠False negatives or positives may occur due to technical issues
  • ⚠Not suitable for monitoring disease activity

Risks & Considerations

  • ●Minor bruising or pain at the puncture site
  • ●Rare risk of infection or fainting

Interfering Factors

  • ●Sample hemolysis
  • ●Improper storage or handling
  • ●Recent blood transfusion

Compare With Similar Tests

TestHLA - B27 Qualitative PCR TestHLA-B27 Quantitative PCRRheumatoid Factor Test
ComparisonHLA - B27 Qualitative PCR Test

Frequently Asked Questions

What is the HLA-B27 Qualitative PCR Test?
It is a diagnostic test that uses PCR technology to detect the presence of the HLA-B27 gene in your DNA, which is linked to autoimmune diseases.
Why is this test recommended?
It is recommended if you have symptoms like chronic back pain, joint inflammation, or eye issues that may indicate an autoimmune condition such as ankylosing spondylitis.
What does a positive result mean?
A positive result means the HLA-B27 gene is detected, indicating an increased risk for HLA-B27 associated autoimmune diseases. It does not confirm a disease diagnosis.
Are there any risks associated with the test?
The risks are minimal and similar to any blood draw, such as bruising or slight pain at the puncture site.
How is the test performed?
A blood sample is collected from your vein and analyzed in a lab using Real Time PCR to detect the HLA-B27 gene.
What is the cost of the test?
The cost is INR 4500, with free home sample collection available across India.
Is the test covered by insurance?
Coverage varies by insurance plan. Check with your provider to see if it is included.
How long does it take to get results?
Results are typically available in 10-12 days after sample collection.
Do I need to fast before the test?
No, fasting is not required for this test.
What sample is required for the test?
A 3 mL whole blood sample in an EDTA (lavender top) tube is needed.
Can the test be done at home?
Yes, free home sample collection is available for online bookings across India.
What should I do if my test is positive?
Consult a rheumatologist or immunologist for further evaluation, diagnosis, and management of potential autoimmune conditions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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