HLA DSA (Donor Specific IgG Antibodies) Class I & II Test
Short Name: HLA DSA Test
Also known as: Donor Specific Antibody Test, HLA Antibody Test, DSA Test
HLA DSA (Donor Specific IgG Antibodies) Class I & II Test test available at DNA Labs India for ₹13,000. Uses Luminex X-Map technology on Blood, Serum samples. Results in Reports are typically available within 10-12 days from sample collection.. Free home collection in 300+ cities across India.
Overview
The purpose of the HLA DSA test is to assess transplant compatibility by detecting donor-specific IgG antibodies, which are associated with antibody-mediated rejection. It is essential for pre-transplant workup to identify sensitized patients and for post-transplant monitoring to prevent organ rejection, ensuring better transplant outcomes.
- Test Code
- 807
- Price
- ₹13,000
- Sample Type
- Blood, Serum
- Result Time
- Reports are typically available within 10-12 days from sample collection.
- Fasting Required
- No
- Method
- Luminex X-Map technology
Sample Collection
Collect specimen preferably 48 hours after dialysis. Doctor's prescription on the letterhead with stamp AND one photograph each of recipient and donor is mandatory. No fasting required, but avoid heavy meals before sample collection.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure: a healthcare professional will draw blood from a vein in the arm using a needle and collection tube.
Report Delivery
Apply pressure to the puncture site with a cotton ball to stop bleeding. Keep the area clean and avoid strenuous activity with the arm for a few hours.
Timeline: Reports are typically available within 10-12 days from sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the HLA DSA test is to assess transplant compatibility by detecting donor-specific IgG antibodies, which are associated with antibody-mediated rejection. It is essential for pre-transplant workup to identify sensitized patients and for post-transplant monitoring to prevent organ rejection, ensuring better transplant outcomes.
How to Prepare
- Obtain a doctor's prescription on official letterhead with stamp
- Provide one recent photograph each of recipient and donor
- Collect sample preferably 48 hours after dialysis if applicable
- Ensure proper labeling of the blood sample with patient details
Doctor's Notes
"This test is crucial for evaluating donor-recipient compatibility and monitoring for antibody-mediated rejection post-transplant, helping to ensure transplant success."
Test Parameters & Specifications
Sample Stability
- Missing or improper doctor's prescription
- Lack of required photographs for recipient and donor
- Sample hemolysis or clotting
- Insufficient sample volume
- Incorrect labeling or identification
Understanding Your Results
Negative
No detectable donor-specific antibodies, suggesting lower risk of antibody-mediated rejection. Compatible for transplant in many cases.
Positive
Detectable donor-specific antibodies present, indicating sensitization and higher risk of antibody-mediated rejection. May require desensitization protocols or alternative donor selection.
Consult your transplant specialist or nephrologist immediately if you experience symptoms like fever, pain around transplant site, swelling, decreased urine output, or shortness of breath post-transplant. Also, discuss all test results with your doctor for personalized management.
Limitations
- ⚠May not detect all antibodies if present below detection threshold
- ⚠Requires accurate donor HLA typing information
- ⚠Results must be interpreted in clinical context
- ⚠False positives can occur due to non-specific binding
- ⚠Limited to IgG antibodies; does not detect IgM or other classes
Risks & Considerations
- ●Minor pain or bruising at the needle insertion site
- ●Rare risk of infection or dizziness
- ●No significant long-term risks associated with the test
Interfering Factors
- ●Recent blood transfusion
- ●Immunosuppressive therapy
- ●Intravenous immunoglobulin (IVIG) treatment
- ●Sample hemolysis or improper storage
- ●Technical errors in sample collection
Frequently Asked Questions
What is the HLA DSA Class I & II Test?
Why is this test important for transplants?
How is the test performed?
What does a positive result mean?
Is the test covered by insurance?
How long does it take to get results?
What preparation is needed for the test?
Are there any risks associated with the test?
Can this test be done at home?
What is the cost of the test?
How accurate is the HLA DSA test?
What should I do if my test results are abnormal?
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₹16,380Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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