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DNA Labs India

Interleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test

DNA Labs India | ISO 9001:2015 Certified

Interleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test

Short Name: IL-6 SARS-CoV-2 Advanced Panel

Also known as: IL-6 COVID-19 Advanced Panel, SARS-CoV-2 Inflammatory and Coagulation Panel, IL-6 Cytokine Storm Panel

Interleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test test available at DNA Labs India for ₹16,380. Uses Real Time RT-PCR, Electrical Impedance, VCS, Spectrophotometry, Indirect ISE, Immunoturbidimetry, Photo-optical clot detection, ECLIA, CLIA, IFCC, CMIA on Serum, EDTA plasma, EDTA whole blood, sodium citrate plasma/whole blood, and nasopharyngeal/oropharyngeal swab in viral transport medium samples. Results in Sample daily by 11 am; report 2 days.. Free home collection in 300+ cities across India.

Physician-supervised advanced panelAdults and children as clinically indicated🏠 Home Collection

🩺 Medically Reviewed By

Overview

This panel helps to assess if a patient is likely to develop complications like a cytokine storm and coagulation defects due to SARS-CoV-2 infection. It combines inflammatory markers, organ function tests, cardiac markers, and coagulation parameters for risk stratification in COVID-19.

Test Code
3507
Price
₹16,380
Sample Type
Serum, EDTA plasma, EDTA whole blood, sodium citrate plasma/whole blood, and nasopharyngeal/oropharyngeal swab in viral transport medium
Result Time
Sample daily by 11 am; report 2 days.
Fasting Required
No
Method
Real Time RT-PCR, Electrical Impedance, VCS, Spectrophotometry, Indirect ISE, Immunoturbidimetry, Photo-optical clot detection, ECLIA, CLIA, IFCC, CMIA
Step 1

Sample Collection

Duly filled Covid-19 Clinical Information Form (Form 44) / SRF ID as mandated by GOI is mandatory AND Duly filled Coagulation Requisition Form (Form 15) is mandatory. Patient should avoid Biotin at least 8 hours prior to specimen collection. Overnight fasting is preferred.

Method: Venepuncture and nasopharyngeal/oropharyngeal swab

Step 2

Laboratory Analysis

A trained phlebotomist will collect blood samples from a vein and nasopharyngeal/oropharyngeal swabs using appropriate infection control precautions.

Step 3

Report Delivery

Apply gentle pressure at the venepuncture site to prevent bruising. Samples are processed and transported at specified temperatures.

Timeline: Sample daily by 11 am; report 2 days.

Patient Instructions

1
Before the Test:Duly filled Covid-19 Clinical Information Form (Form 44) / SRF ID and Coagulation Requisition Form (Form 15) are mandatory. Avoid biotin at least 8 hours prior. Overnight fasting is preferred.
2
During the Test:A trained phlebotomist will collect blood samples from a vein and nasopharyngeal/oropharyngeal swabs using appropriate infection control precautions.
3
After the Test:Apply gentle pressure at the venepuncture site. You may resume normal activities unless advised otherwise by your physician.

About This Test

Who Should Get This Test

This panel helps to assess if a patient is likely to develop complications like a cytokine storm and coagulation defects due to SARS-CoV-2 infection. It combines inflammatory markers, organ function tests, cardiac markers, and coagulation parameters for risk stratification in COVID-19.

How to Prepare

  • Carry duly filled Covid-19 Clinical Information Form (Form 44) / SRF ID.
  • Carry duly filled Coagulation Requisition Form (Form 15).
  • Avoid biotin supplements at least 8 hours before collection.
  • Overnight fasting is preferred.
  • Collect serum from two SST tubes and separate EDTA plasma within 2 hours.
  • Mix blue top sodium citrate tubes thoroughly by inversion.
  • Transport sodium citrate whole blood to the lab within 4 hours or prepare platelet-poor plasma and freeze immediately.
  • Collect nasopharyngeal and oropharyngeal swabs in viral transport medium and ship refrigerated; do not freeze.

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"This panel is useful for risk stratification in SARS-CoV-2 positive patients with moderate to severe disease. Elevated IL-6, CRP, ferritin, and D-dimer may indicate a hyperinflammatory state and can guide timely escalation or immunomodulatory therapy. Results should always be interpreted with clinical status and current guidelines."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum, EDTA plasma, EDTA whole blood, sodium citrate plasma/whole blood, and nasopharyngeal/oropharyngeal swab in viral transport medium
Sample VolumeSerum: 5 mL (4 mL min.) from 2 SSTs; EDTA plasma: 2 mL (1 mL min.); EDTA whole blood: 3 mL (2 mL min.); Sodium citrate whole blood: 3 mL; NP/OP swab in VTM
ContainerSST, Lavender Top (EDTA), Blue Top (Sodium Citrate), Viral Transport Medium
Collection MethodVenepuncture and nasopharyngeal/oropharyngeal swab

Sample Stability

Serum: ship refrigerated or frozen
EDTA plasma: separate within 2 hours; ship refrigerated or frozen
EDTA whole blood: ship refrigerated; do not freeze
Sodium citrate whole blood: transport within 4 hours; if not possible, prepare PPP and freeze immediately
NP/OP swab in VTM: ship refrigerated; do not freeze
Sample Rejection Criteria:
  • Insufficient sample volume
  • Sample collected in wrong tube
  • Frozen whole blood where refrigeration is specified
  • Thawed frozen sample where frozen shipping is required
  • Grossly haemolysed or lipemic sample
  • Missing mandatory requisition forms or SRF ID

Understanding Your Results

Interpretation of this panel should consider all parameters together rather than any single value. SARS-CoV-2 PCR detects viral RNA. Elevated IL-6, CRP, ferritin, D-dimer and procalcitonin may indicate a hyperinflammatory or pro-thrombotic state. Cardiac markers such as high-sensitivity troponin I and NT-proBNP may suggest cardiac involvement.
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Detected indicates presence of viral RNA; Not Detected does not rule out infection if sampling or timing is suboptimal.

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Elevated levels can occur in cytokine release syndrome and severe COVID-19; higher levels may indicate greater inflammatory burden.

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Elevated values suggest an acute inflammatory or hyperinflammatory response; very high ferritin may be seen in cytokine storm.

📊

Elevated D-dimer or prolonged PT may indicate coagulation activation and increased thrombotic risk.

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Elevated values may suggest myocardial injury or cardiac stress associated with severe COVID-19.

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Abnormal liver or kidney function tests may indicate organ involvement and influence treatment decisions.

⚠️ When to Consult a Doctor:

If you develop fever, cough, shortness of breath, persistent chest pain, confusion, or bluish lips or face, seek emergency medical care immediately.

Limitations

  • This panel is not a standalone diagnostic test and should be interpreted with clinical findings.
  • It may not predict all complications in every patient.
  • Results can vary with time of testing, co-existing infections, and treatment already received.
  • Reference ranges may vary by laboratory, age, sex, and clinical context.

Risks & Considerations

  • Mild pain or bruising at venepuncture site
  • Transient discomfort during swab collection
  • Rare risk of infection at needle site
  • Vasovagal reaction such as dizziness

Interfering Factors

  • Recent biotin intake
  • Haemolysis
  • Lipemia
  • Improper sample handling or delayed transport
  • Anticoagulant therapy may alter coagulation results

Compare With Similar Tests

TestInterleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test
ComparisonInterleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test

Frequently Asked Questions

What is the Interleukin-6 (IL-6) SARS-CoV-2 Advanced Panel Test?
It is a COVID-19 risk stratification panel that measures IL-6 and other markers such as CRP, ferritin, D-dimer, PT, cardiac markers, and organ function tests to assess the likelihood of cytokine storm and coagulation defects.
Why is IL-6 measured in COVID-19?
IL-6 is a protein produced in response to inflammation. Studies show that IL-6 levels tend to be elevated in patients with severe COVID-19 symptoms, so it helps identify patients at risk for severe disease.
Does this test diagnose COVID-19?
This panel includes SARS-CoV-2 qualitative PCR, which can detect viral RNA, but the panel is mainly used for risk stratification and not solely as a standalone diagnostic test.
What samples are required for this test?
It requires serum, EDTA plasma, EDTA whole blood, sodium citrate whole blood or plasma, and nasopharyngeal/oropharyngeal swabs in viral transport medium.
Do I need to fast before this test?
Overnight fasting is preferred. You should also avoid biotin at least 8 hours before specimen collection.
What is the cost of this test at DNA Labs India?
The cost is INR 16,380.
How long does it take to get reports?
Samples are processed daily by 11 am and reports are available in 2 days.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings for this test across India.
What does an elevated IL-6 level mean?
An elevated IL-6 level may indicate increased inflammation and has been associated with severe COVID-19 and cytokine release syndrome.
What other markers are included in this panel?
The panel includes CBC, NLR, SARS-CoV-2 PCR, IL-6, LFT, KFT, LDH, troponin-I high sensitive, NT-proBNP, D-dimer, PT, procalcitonin, ferritin, and CRP.
Who should get this test?
It is typically used for patients with known or suspected COVID-19 who have moderate to severe symptoms, or those needing risk assessment for cytokine storm and coagulopathy.
Are there any special instructions before collection?
Yes, duly filled Covid-19 Clinical Information Form (Form 44) / SRF ID and Coagulation Requisition Form (Form 15) are mandatory. Avoid biotin before collection and overnight fasting is preferred.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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