Skip to main content
DNA Labs India

KRAS Mutation Codon 12 & 13 Test

DNA Labs India | ISO 9001:2015 Certified

KRAS Mutation Codon 12 & 13 Test

Short Name: KRAS Codon 12 & 13 Mutation Test

Also known as: KRAS Codon 12 and 13 Mutation Analysis, KRAS Gene Mutation Test

KRAS Mutation Codon 12 & 13 Test test available at DNA Labs India for ₹10,000. Uses PCR, Fragment analysis on Formalin fixed paraffin embedded tissue block samples. Results in Reports typically available within 6-7 days after sample receipt.. Free home collection in 300+ cities across India.

Molecular Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To detect mutations in codons 12 and 13 of the KRAS gene, which can guide targeted cancer therapy and treatment decisions.

Test Code
1146
Price
₹10,000
Sample Type
Formalin fixed paraffin embedded tissue block
Result Time
Reports typically available within 6-7 days after sample receipt.
Fasting Required
No
Method
PCR, Fragment analysis
Step 1

Sample Collection

Ensure the NGS Test Requisition Form (Form 40) is duly filled and submitted with the sample.

Method: Biopsy or surgery sample

Step 2

Laboratory Analysis

Collect tissue sample during biopsy or surgery, ensuring at least 10% tumor content.

Step 3

Report Delivery

Ship the formalin fixed paraffin embedded tissue block at room temperature as per instructions.

Timeline: Reports typically available within 6-7 days after sample receipt.

Patient Instructions

1
Before the Test:Complete the NGS Test Requisition Form (Form 40) and ensure sample is properly collected and shipped.
2
During the Test:Sample analysis performed using PCR and fragment analysis to detect KRAS mutations.
3
After the Test:Receive report via online portal, email, or WhatsApp as per selected delivery method.

About This Test

Who Should Get This Test

To detect mutations in codons 12 and 13 of the KRAS gene, which can guide targeted cancer therapy and treatment decisions.

How to Prepare

  • Submit formalin fixed paraffin embedded tissue block.
  • Ship at room temperature.
  • Block should have at least 10% tumor tissue.
  • Duly filled NGS Test Requisition Form (Form 40) is mandatory.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"KRAS mutation testing is crucial for identifying targeted therapy options in cancer patients, particularly for colorectal, pancreatic, and lung cancers."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded tissue block
ContainerFormalin fixed paraffin embedded tissue block
Collection MethodBiopsy or surgery sample
Sample Rejection Criteria:
  • Insufficient tumor tissue (<10%)
  • Improperly fixed or embedded tissue
  • Missing or incomplete requisition form

Understanding Your Results

Results indicate the presence or absence of mutations in KRAS codons 12 and 13, which can impact cancer treatment strategies.
📊

Mutation detected

Presence of KRAS mutation may indicate resistance to certain targeted therapies, guiding alternative treatment options.

📊

No mutation detected

Absence of KRAS mutation in codons 12 and 13 may suggest eligibility for specific targeted therapies, subject to further clinical evaluation.

⚠️ When to Consult a Doctor:

Consult your oncologist immediately after receiving test results to discuss treatment implications and next steps.

Limitations

  • ⚠Test only covers codons 12 and 13 of the KRAS gene.
  • ⚠Does not detect all possible KRAS mutations.
  • ⚠Results are specific to the sample provided and may not reflect overall tumor heterogeneity.

Risks & Considerations

  • ●Minimal risks associated with sample collection from biopsy or surgery, such as infection or bleeding.

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during sample handling
  • ●Insufficient tumor tissue content

Frequently Asked Questions

What is the KRAS Mutation Codon 12 & 13 Test?
It is a genetic test that identifies mutations in codons 12 and 13 of the KRAS gene, which are commonly found in cancers like colorectal, pancreatic, and lung cancer.
Why is this test important for cancer treatment?
KRAS mutations can affect the effectiveness of targeted therapies, such as EGFR inhibitors, so testing helps guide personalized treatment decisions.
How is the sample collected for this test?
The test requires a formalin fixed paraffin embedded tissue block, typically obtained during a biopsy or surgery.
What is the cost of the KRAS Mutation Codon 12 & 13 Test?
The test costs INR 10000 at DNA Labs India, with free home sample collection available in many cities.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
How long does it take to get the test results?
Results are typically available within 6-7 days after sample receipt, with delivery via online portal, email, or WhatsApp.
What do the test results indicate?
Results show whether KRAS mutations are detected or not, which can influence cancer treatment strategies, such as eligibility for targeted therapy.
Are there any risks associated with the test?
The test itself has minimal risks; risks are primarily related to the biopsy or surgery procedure for sample collection.
How should I prepare for the test?
Ensure the NGS Test Requisition Form (Form 40) is completed, and the tissue sample is properly collected and shipped as per instructions.
Does this test detect all KRAS mutations?
No, this test specifically targets mutations in codons 12 and 13 of the KRAS gene; other mutations may not be detected.
Is the test covered by insurance in India?
Coverage varies by insurance scheme; it is advisable to check with your insurance provider for specific coverage details.
Where can I get the KRAS Mutation Codon 12 & 13 Test done?
You can book the test through DNA Labs India, with home collection available in numerous cities across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

B-Cell Rearrangement Detection Test

₹22,000

Acute Lymphoblastic Leukemia (ALL) Cytogenetics Panel Test

₹20,000

Epstein-Barr Virus Early RNA (EBER-ISH) In-Situ-Hybridization Test

₹6,000

OncoPro NCCN Lung Cancer Panel with PD-L1 Test

₹140,400

Acute Myeloid Leukemia (AML) Cytogenetics Panel Test

₹23,000

AML ETO t(8;21) Gene Rearrangement PCR Qualitative Test

₹6,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.