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DNA Labs India

KRAS & NRAS Mutation Analysis Panel Test

DNA Labs India | ISO 9001:2015 Certified

KRAS & NRAS Mutation Analysis Panel Test

Short Name: KRAS/NRAS Mutation Panel

Also known as: RAS Mutation Analysis, KRAS/NRAS Gene Panel, Cancer Mutation Panel

KRAS & NRAS Mutation Analysis Panel Test test available at DNA Labs India for ₹15,000. Uses PCR, Fragment analysis, Sequencing on Formalin fixed paraffin embedded tissue block samples. Results in Reports typically available within 5-7 business days after sample receipt.. Free home collection in 300+ cities across India.

Molecular Genetic TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to detect mutations in KRAS and NRAS genes to guide cancer treatment decisions, such as avoiding ineffective therapies and selecting targeted treatments for improved patient outcomes.

Test Code
1151
Price
₹15,000
Sample Type
Formalin fixed paraffin embedded tissue block
Result Time
Reports typically available within 5-7 business days after sample receipt.
Fasting Required
No
Method
PCR, Fragment analysis, Sequencing
Step 1

Sample Collection

Ensure the tissue sample is collected via biopsy or surgery. Fill the NGS Test Requisition Form (Form 40) accurately.

Method: Biopsy or surgical tissue sample

Step 2

Laboratory Analysis

Tissue sample is preserved in formalin and embedded in paraffin for analysis.

Step 3

Report Delivery

Sample is shipped to the lab at room temperature; no special post-collection care needed.

Timeline: Reports typically available within 5-7 business days after sample receipt.

Patient Instructions

1
Before the Test:Complete the requisition form and ensure sample quality. No fasting required.
2
During the Test:DNA extraction from tissue, followed by PCR and sequencing to detect mutations.
3
After the Test:Results analyzed and reported by pathologist; no immediate post-test precautions.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in KRAS and NRAS genes to guide cancer treatment decisions, such as avoiding ineffective therapies and selecting targeted treatments for improved patient outcomes.

How to Prepare

  • Submit formalin fixed paraffin embedded tissue block
  • Block should have at least 10% tumor tissue
  • Ship at room temperature
  • Duly filled NGS Test Requisition Form (Form 40) is mandatory

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is essential for identifying mutations that affect response to targeted therapies, such as anti-EGFR agents in colorectal cancer, guiding personalized treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded tissue block
Sample VolumeAdequate tissue with at least 10% tumor content
ContainerTissue block container
Collection MethodBiopsy or surgical tissue sample

Sample Stability

Room TemperatureStable for shipping
Long-term StorageAs per lab protocol
Sample Rejection Criteria:
  • Tissue block with less than 10% tumor content
  • Missing or incomplete NGS Test Requisition Form
  • Sample degradation or contamination

Understanding Your Results

Results indicate the presence or absence of mutations in KRAS and NRAS genes, which are biomarkers for cancer prognosis and treatment response.
📊

Positive for KRAS Mutation

May indicate resistance to anti-EGFR therapies in colorectal cancer; alternative treatments needed.

📊

Positive for NRAS Mutation

Associated with certain cancers; influences treatment selection.

📊

Negative for Mutations

Standard therapies may be effective; further testing recommended if clinically indicated.

⚠️ When to Consult a Doctor:

Consult your oncologist immediately after receiving results to discuss personalized treatment options based on mutation status.

Limitations

  • Detects only known mutations; novel variants may be missed
  • Not a standalone diagnostic tool; must be used with clinical evaluation
  • Results may vary based on tumor heterogeneity

Risks & Considerations

  • Minimal risk from tissue biopsy procedure if sample not already available
  • No direct risks from the genetic test itself

Interfering Factors

  • Poor sample quality or insufficient tumor tissue
  • Degraded DNA from improper sample storage
  • Contamination during sample processing

Compare With Similar Tests

TestKRAS & NRAS Mutation Analysis Panel TestEGFR Mutation AnalysisBRAF Mutation Test
ComparisonKRAS & NRAS Mutation Analysis Panel Test

Frequently Asked Questions

What is the KRAS & NRAS Mutation Analysis Panel Test?
It is a genetic test that detects mutations in the KRAS and NRAS genes, which are associated with various cancers and can affect treatment efficacy.
Why is this test important for cancer patients?
It helps oncologists determine if targeted therapies will be effective, allowing for personalized treatment plans and avoiding ineffective drugs.
What sample is required for the test?
A formalin fixed paraffin embedded tissue block with at least 10% tumor content is needed, collected via biopsy or surgery.
How is the test performed?
The sample is analyzed using PCR, fragment analysis, and sequencing to identify mutations in KRAS and NRAS genes.
What is the cost of the test in India?
The test costs INR 15,000 at DNA Labs India, with home sample collection available in many cities.
Is home sample collection available?
Yes, free home collection is offered for online bookings across India, including major cities like Mumbai, Delhi, and Bangalore.
How long does it take to get results?
Results are typically available within 5-7 business days after the sample is received at the lab.
Who should undergo this test?
Patients with colorectal, lung, or pancreatic cancer, especially those considering targeted therapies or with treatment resistance.
What do positive results mean?
Positive results indicate the presence of mutations, which may affect treatment response, such as resistance to anti-EGFR drugs in colorectal cancer.
Are there any risks associated with the test?
The test itself has minimal risks; any risks are related to the biopsy procedure if a new tissue sample is needed.
How should I prepare for the test?
Ensure the tissue sample is properly collected and the NGS Test Requisition Form is filled out completely.
Can this test be used for all types of cancer?
It is primarily for cancers where KRAS and NRAS mutations are relevant, such as colorectal, lung, and pancreatic cancers; consult your doctor for specifics.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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