Liquid Bx. Cell Free BRAF Test
Short Name: Liquid Bx BRAF
Also known as: Cell-free BRAF mutation test, Liquid biopsy BRAF, ctDNA BRAF
Liquid Bx. Cell Free BRAF Test test available at DNA Labs India for ₹18,000. Uses Droplet Digital PCR (ddPCR) on Peripheral Blood samples. Results in Reports are typically available within 5-7 business days after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the Liquid Bx Cell Free BRAF test is to detect BRAF mutations in circulating tumor DNA (ctDNA) from a blood sample. This aids in the diagnosis, prognosis, and monitoring of cancers associated with BRAF mutations, such as melanoma, colorectal carcinoma, and thyroid cancer. It is particularly useful when a tissue biopsy is not feasible or when repeated sampling is needed to monitor treatment response or resistance. The test helps oncologists select appropriate targeted therapies, such as BRAF inhibitors, and assess the effectiveness of ongoing treatment.
- Test Code
- 6113
- CPT Code
- 81445
- ICD Code
- C43.9
- Price
- ₹18,000
- Sample Type
- Peripheral Blood
- Result Time
- Reports are typically available within 5-7 business days after sample collection.
- Fasting Required
- No
- Method
- Droplet Digital PCR (ddPCR)
Sample Collection
No special preparation is required. A doctor's prescription is recommended. Inform your healthcare provider about any medications you are taking.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.
Report Delivery
You may resume normal activities immediately. Apply pressure to the puncture site to prevent bruising.
Timeline: Reports are typically available within 5-7 business days after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Liquid Bx Cell Free BRAF test is to detect BRAF mutations in circulating tumor DNA (ctDNA) from a blood sample. This aids in the diagnosis, prognosis, and monitoring of cancers associated with BRAF mutations, such as melanoma, colorectal carcinoma, and thyroid cancer. It is particularly useful when a tissue biopsy is not feasible or when repeated sampling is needed to monitor treatment response or resistance. The test helps oncologists select appropriate targeted therapies, such as BRAF inhibitors, and assess the effectiveness of ongoing treatment.
How to Prepare
- Use Streck tube for blood collection
- Fill the tube to the indicated mark
- Mix gently by inverting 8-10 times
- Do not refrigerate or freeze the sample
- Transport at ambient temperature to the laboratory within 48 hours
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Liquid biopsy for BRAF mutations is a breakthrough for patients with suspected melanoma, colorectal, or thyroid cancers. It offers a minimally invasive way to guide targeted therapy and monitor treatment response."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Clotted sample
- Incorrect tube used
- Insufficient volume
- Sample received after 48 hours
Understanding Your Results
BRAF V600E Mutation Detected
Positive for BRAF V600E mutation. Targeted therapy with BRAF inhibitors may be considered. Consult oncologist.
BRAF V600E Mutation Not Detected
No BRAF V600E mutation detected in the sample. Other mutations may be present. Clinical correlation advised.
BRAF V600K Mutation Detected
Positive for BRAF V600K mutation. Targeted therapy options may be discussed with oncologist.
Other BRAF Mutation Detected
A non-V600 BRAF mutation is present. Clinical significance varies; consult oncologist for interpretation.
Consult your oncologist if you have been diagnosed with a cancer that may harbor BRAF mutations, or if you are on BRAF-targeted therapy and need monitoring. Also, if you experience new or worsening symptoms, seek medical advice.
Limitations
- ⚠May not detect mutations if tumor DNA is below the limit of detection
- ⚠Results should be correlated with clinical findings
- ⚠Not a substitute for tissue biopsy in all cases
- ⚠Only detects BRAF mutations, not other genetic alterations
Risks & Considerations
- ●Minimal risk of bruising or bleeding at the puncture site
- ●Rare risk of infection
- ●Fainting or dizziness during blood draw
Interfering Factors
- ●Hemolysis or improper sample handling
- ●Insufficient blood volume
- ●Delay in processing beyond recommended time
- ●Contamination during collection
Compare With Similar Tests
| Test | Liquid Bx. Cell Free BRAF | ||||
|---|---|---|---|---|---|
| Comparison | Liquid Bx. Cell Free BRAF |
Frequently Asked Questions
What is Liquid Bx Cell Free BRAF test?
How is the test performed?
Is fasting required?
What is the cost of the test?
How long does it take to get results?
Is home sample collection available?
What is the sample type?
What cancers are associated with BRAF mutations?
Can this test replace a tissue biopsy?
Is a doctor's prescription required?
What is the accuracy of the test?
Are there any risks?
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