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DNA Labs India

Liquid Bx. Cell Free BRAF Test

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Liquid Bx. Cell Free BRAF Test

Short Name: Liquid Bx BRAF

Also known as: Cell-free BRAF mutation test, Liquid biopsy BRAF, ctDNA BRAF

Liquid Bx. Cell Free BRAF Test test available at DNA Labs India for ₹18,000. Uses Droplet Digital PCR (ddPCR) on Peripheral Blood samples. Results in Reports are typically available within 5-7 business days after sample collection.. Free home collection in 300+ cities across India.

Liquid BiopsyAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

The primary purpose of the Liquid Bx Cell Free BRAF test is to detect BRAF mutations in circulating tumor DNA (ctDNA) from a blood sample. This aids in the diagnosis, prognosis, and monitoring of cancers associated with BRAF mutations, such as melanoma, colorectal carcinoma, and thyroid cancer. It is particularly useful when a tissue biopsy is not feasible or when repeated sampling is needed to monitor treatment response or resistance. The test helps oncologists select appropriate targeted therapies, such as BRAF inhibitors, and assess the effectiveness of ongoing treatment.

Test Code
6113
CPT Code
81445
ICD Code
C43.9
Price
₹18,000
Sample Type
Peripheral Blood
Result Time
Reports are typically available within 5-7 business days after sample collection.
Fasting Required
No
Method
Droplet Digital PCR (ddPCR)
Step 1

Sample Collection

No special preparation is required. A doctor's prescription is recommended. Inform your healthcare provider about any medications you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You may resume normal activities immediately. Apply pressure to the puncture site to prevent bruising.

Timeline: Reports are typically available within 5-7 business days after sample collection.

Patient Instructions

1
Before the Test:No special preparation required. Ensure you have a doctor's prescription if applicable.
2
During the Test:A blood sample is drawn from your arm. The process takes about 5 minutes.
3
After the Test:You can resume normal activities. Keep the puncture site clean and dry.

About This Test

Who Should Get This Test

The primary purpose of the Liquid Bx Cell Free BRAF test is to detect BRAF mutations in circulating tumor DNA (ctDNA) from a blood sample. This aids in the diagnosis, prognosis, and monitoring of cancers associated with BRAF mutations, such as melanoma, colorectal carcinoma, and thyroid cancer. It is particularly useful when a tissue biopsy is not feasible or when repeated sampling is needed to monitor treatment response or resistance. The test helps oncologists select appropriate targeted therapies, such as BRAF inhibitors, and assess the effectiveness of ongoing treatment.

How to Prepare

  • Use Streck tube for blood collection
  • Fill the tube to the indicated mark
  • Mix gently by inverting 8-10 times
  • Do not refrigerate or freeze the sample
  • Transport at ambient temperature to the laboratory within 48 hours

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Liquid biopsy for BRAF mutations is a breakthrough for patients with suspected melanoma, colorectal, or thyroid cancers. It offers a minimally invasive way to guide targeted therapy and monitor treatment response."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypePeripheral Blood
Sample Volume10 mL
ContainerStreck Tube
Collection MethodVenipuncture

Sample Stability

Ambient temperature: 48 hours
Refrigerated: Not recommended
Frozen: Not recommended
Sample Rejection Criteria:
  • Hemolyzed sample
  • Clotted sample
  • Incorrect tube used
  • Insufficient volume
  • Sample received after 48 hours

Understanding Your Results

The presence of BRAF mutations, especially V600E, indicates a potential response to BRAF inhibitors. Absence of mutation suggests no detectable mutation in the blood sample, but does not rule out the possibility of a mutation below the detection limit.
📊

BRAF V600E Mutation Detected

Positive for BRAF V600E mutation. Targeted therapy with BRAF inhibitors may be considered. Consult oncologist.

📊

BRAF V600E Mutation Not Detected

No BRAF V600E mutation detected in the sample. Other mutations may be present. Clinical correlation advised.

📊

BRAF V600K Mutation Detected

Positive for BRAF V600K mutation. Targeted therapy options may be discussed with oncologist.

📊

Other BRAF Mutation Detected

A non-V600 BRAF mutation is present. Clinical significance varies; consult oncologist for interpretation.

⚠️ When to Consult a Doctor:

Consult your oncologist if you have been diagnosed with a cancer that may harbor BRAF mutations, or if you are on BRAF-targeted therapy and need monitoring. Also, if you experience new or worsening symptoms, seek medical advice.

Limitations

  • May not detect mutations if tumor DNA is below the limit of detection
  • Results should be correlated with clinical findings
  • Not a substitute for tissue biopsy in all cases
  • Only detects BRAF mutations, not other genetic alterations

Risks & Considerations

  • Minimal risk of bruising or bleeding at the puncture site
  • Rare risk of infection
  • Fainting or dizziness during blood draw

Interfering Factors

  • Hemolysis or improper sample handling
  • Insufficient blood volume
  • Delay in processing beyond recommended time
  • Contamination during collection

Compare With Similar Tests

TestLiquid Bx. Cell Free BRAF
ComparisonLiquid Bx. Cell Free BRAF

Frequently Asked Questions

What is Liquid Bx Cell Free BRAF test?
It is a non-invasive blood test that detects BRAF mutations in cell-free DNA, commonly used in oncology for diagnosis and monitoring.
How is the test performed?
A blood sample is collected in a Streck tube and analyzed using Droplet Digital PCR (ddPCR) technology.
Is fasting required?
No, fasting is not required for this test.
What is the cost of the test?
The cost is INR 18,000, which includes home sample collection.
How long does it take to get results?
Reports are available within 5-7 days.
Is home sample collection available?
Yes, free home sample collection is available across major cities in India.
What is the sample type?
Peripheral blood collected in a Streck tube.
What cancers are associated with BRAF mutations?
Melanoma, colorectal cancer, and thyroid cancer are commonly associated.
Can this test replace a tissue biopsy?
It can be an alternative when biopsy is not feasible, but clinical correlation is essential.
Is a doctor's prescription required?
Yes, a doctor's prescription is recommended, except for surgery or pregnancy cases.
What is the accuracy of the test?
The test has high accuracy using ddPCR technology, but results should be interpreted by a specialist.
Are there any risks?
Risks are minimal, similar to a routine blood draw.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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