Lung Cancer Panel 7 (EGFR,BRAF,ALK1,ROS1,MET) Test
Short Name: Lung Cancer Panel 7
Also known as: Lung Cancer Mutation Panel, EGFR BRAF ALK ROS1 MET Panel
Lung Cancer Panel 7 (EGFR,BRAF,ALK1,ROS1,MET) Test test available at DNA Labs India for ₹36,000. Uses FISH, Sanger Sequencing on Tumor tissue (paraffin embedded block) samples. Results in Reports are typically available within 5-7 working days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Lung Cancer Panel 7 is to identify somatic mutations in EGFR, BRAF, ALK1, ROS1, and MET genes, which are predictive biomarkers for targeted therapy in lung cancer. Detection of these alterations helps in selecting appropriate targeted drugs, predicting response to therapy, and monitoring resistance mechanisms.
- Test Code
- 6122
- CPT Code
- 81445
- ICD Code
- C34.90
- Price
- ₹36,000
- Sample Type
- Tumor tissue (paraffin embedded block)
- Result Time
- Reports are typically available within 5-7 working days after sample receipt.
- Fasting Required
- No
- Method
- FISH, Sanger Sequencing
Sample Collection
No special preparation required. A doctor's prescription is mandatory. Inform your doctor about any medications you are taking.
Method: Biopsy or surgical resection
Laboratory Analysis
The sample is collected via biopsy or surgical resection. The tissue is placed in a paraffin block for transport.
Report Delivery
No specific aftercare required. You can resume normal activities immediately.
Timeline: Reports are typically available within 5-7 working days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Lung Cancer Panel 7 is to identify somatic mutations in EGFR, BRAF, ALK1, ROS1, and MET genes, which are predictive biomarkers for targeted therapy in lung cancer. Detection of these alterations helps in selecting appropriate targeted drugs, predicting response to therapy, and monitoring resistance mechanisms.
How to Prepare
- Tumor tissue block must be from the primary or metastatic site
- Provide the pathology report with the block
- Ensure the block is properly labeled with patient ID
- If sending slides, include 5-10 unstained sections of 4-5 micron thickness
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This panel is essential for identifying actionable mutations in non-small cell lung cancer (NSCLC), guiding targeted therapy decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample with insufficient tumor cells
- Decalcified tissue (bone) that may have degraded DNA
- Block with no tumor tissue
- Unlabeled or mislabeled samples
- Samples received in improper fixative (e.g., Bouin's solution)
Understanding Your Results
EGFR mutation positive
Eligible for EGFR TKIs (e.g., erlotinib, osimertinib)
BRAF V600E mutation
Eligible for BRAF inhibitors (e.g., dabrafenib) combined with MEK inhibitors
ALK rearrangement positive
Eligible for ALK inhibitors (e.g., crizotinib, alectinib)
ROS1 rearrangement positive
Eligible for ROS1 inhibitors (e.g., crizotinib, entrectinib)
MET amplification or exon 14 skipping
Eligible for MET inhibitors (e.g., capmatinib, crizotinib)
No mutations detected
Consider alternative therapies or further testing for other biomarkers
Consult your oncologist if you have been diagnosed with lung cancer and are planning treatment. Also, if you experience new or worsening symptoms such as persistent cough, chest pain, or unexplained weight loss, seek medical advice.
Limitations
- ⚠This panel does not detect all possible mutations; other genes may be relevant
- ⚠Sanger sequencing has limited sensitivity for low allele frequency mutations (<15-20%)
- ⚠FISH may miss atypical rearrangements
- ⚠Results are qualitative and require clinical correlation
- ⚠Tumor heterogeneity may lead to false negatives
Risks & Considerations
- ●No significant risks associated with the test itself
- ●Biopsy procedure may carry minimal risks (bleeding, infection) as per standard care
Interfering Factors
- ●Insufficient tumor content (<20%) in the sample
- ●Decalcification of bone tissue may degrade DNA
- ●Fixation in formalin for more than 24 hours can cause DNA cross-linking
- ●Necrotic tissue may yield poor quality DNA
- ●Concurrent use of anticoagulants may affect blood samples (not applicable for tissue)
Compare With Similar Tests
| Test | Lung Cancer Panel 7 (EGFR,BRAF,ALK1,ROS1,MET) | Lung Cancer Panel 5 | Single Gene EGFR Test | NGS-based Comprehensive Panel |
|---|---|---|---|---|
| Comparison | Lung Cancer Panel 7 (EGFR,BRAF,ALK1,ROS1,MET) |
Frequently Asked Questions
What is the cost of the Lung Cancer Panel 7 test?
What sample is required for this test?
Is fasting required before the test?
How long does it take to get results?
Which genes are analyzed in this panel?
Is this test covered by insurance?
Can this test be done at home?
Who should get this test?
What is the method used for testing?
Are there any risks associated with the test?
Can this test detect all lung cancer mutations?
Is a doctor's prescription required?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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