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DNA Labs India

Lung Cancer Panel 8 (EGFR,BRAF,ALK,ROS,MET,PDL1) Test

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Lung Cancer Panel 8 (EGFR,BRAF,ALK,ROS,MET,PDL1) Test

Short Name: Lung Cancer Panel 8

Also known as: Lung Cancer Comprehensive Panel, EGFR BRAF ALK ROS MET PDL1 Panel, Lung Cancer Mutation Panel 8

Lung Cancer Panel 8 (EGFR,BRAF,ALK,ROS,MET,PDL1) Test test available at DNA Labs India for ₹45,000. Uses FISH, Sanger Sequencing, IHC on Tumor tissue (paraffin-embedded block) samples. Results in Reports are typically available within 5-7 days after the sample reaches the laboratory.. Free home collection in 300+ cities across India.

Molecular PathologyAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Lung Cancer Panel 8 is to detect specific genetic mutations and rearrangements that drive lung cancer. This information is vital for personalized treatment decisions, predicting response to targeted therapies, and identifying patients who may benefit from immunotherapy. Early detection of these biomarkers can significantly impact prognosis and survival.

Test Code
6123
CPT Code
81445
ICD Code
C34.9
Price
₹45,000
Sample Type
Tumor tissue (paraffin-embedded block)
Result Time
Reports are typically available within 5-7 days after the sample reaches the laboratory.
Fasting Required
No
Method
FISH, Sanger Sequencing, IHC
Step 1

Sample Collection

No special preparation required. A doctor's prescription is necessary. Inform your doctor about any medications you are taking.

Method: Biopsy or surgical resection

Step 2

Laboratory Analysis

The sample is collected via biopsy or surgical resection. The procedure is performed by a qualified healthcare professional.

Step 3

Report Delivery

The tissue sample is sent to the laboratory for analysis. Results are typically available within 5-7 days.

Timeline: Reports are typically available within 5-7 days after the sample reaches the laboratory.

Patient Instructions

1
Before the Test:No special preparation is needed. Ensure you have a doctor's prescription and provide the tumor tissue sample.
2
During the Test:The sample is processed in the laboratory. The testing process involves DNA extraction, PCR, sequencing, and IHC.
3
After the Test:You will receive a detailed report with results and interpretation. Discuss the results with your oncologist to plan treatment.

About This Test

Who Should Get This Test

The purpose of the Lung Cancer Panel 8 is to detect specific genetic mutations and rearrangements that drive lung cancer. This information is vital for personalized treatment decisions, predicting response to targeted therapies, and identifying patients who may benefit from immunotherapy. Early detection of these biomarkers can significantly impact prognosis and survival.

How to Prepare

  • Tumor tissue block or slides must be provided
  • Ensure the sample is properly labeled with patient details
  • Avoid freezing the sample
  • Ship the sample at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This panel is essential for guiding targeted therapy in non-small cell lung cancer. Identifying actionable mutations like EGFR, ALK, ROS1, and MET helps select the most effective treatment, improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue (paraffin-embedded block)
Sample Volume1 tissue block or 5-10 unstained slides
ContainerParaffin block or slides in a sealed container
Collection MethodBiopsy or surgical resection

Sample Stability

Paraffin-embedded tissue: stable at room temperature for years
Unstained slides: stable for up to 2 weeks at room temperature
Sample Rejection Criteria:
  • Insufficient tumor content (<20%)
  • Sample with extensive necrosis
  • Decalcified bone tissue
  • Improperly labeled or damaged sample

Understanding Your Results

The results of the Lung Cancer Panel 8 should be interpreted by a qualified oncologist in the context of the patient's clinical history and other diagnostic findings.
📊

EGFR mutation positive

Indicates sensitivity to EGFR tyrosine kinase inhibitors (e.g., erlotinib, osimertinib).

📊

ALK rearrangement positive

Indicates benefit from ALK inhibitors (e.g., crizotinib, alectinib).

📊

ROS1 rearrangement positive

Indicates benefit from ROS1 inhibitors (e.g., crizotinib, entrectinib).

📊

MET exon 14 skipping mutation

Indicates potential benefit from MET inhibitors (e.g., capmatinib).

📊

BRAF V600E mutation

Indicates potential benefit from BRAF inhibitors (e.g., dabrafenib) combined with MEK inhibitors.

📊

PDL1 TPS ≥50%

High expression suggests likely response to PD-1/PD-L1 inhibitors (e.g., pembrolizumab).

⚠️ When to Consult a Doctor:

Consult your oncologist if you have been diagnosed with lung cancer and are considering targeted therapy or immunotherapy. Also, consult if you experience new or worsening symptoms.

Limitations

  • This panel does not detect all possible lung cancer mutations
  • Results are dependent on tumor tissue quality and quantity
  • PDL1 IHC results may vary with different antibody clones
  • Negative results do not rule out the presence of other genetic alterations

Risks & Considerations

  • Biopsy procedure may carry a small risk of bleeding or infection
  • No significant risks associated with the test itself

Interfering Factors

  • Inadequate tumor tissue sample
  • Decalcification of bone samples
  • Necrotic tissue
  • Fixation artifacts
  • Recent chemotherapy or radiation may affect results

Compare With Similar Tests

TestLung Cancer Panel 8 (EGFR,BRAF,ALK,ROS,MET,PDL1)Lung Cancer Panel 5Lung Cancer Panel 10
ComparisonLung Cancer Panel 8 (EGFR,BRAF,ALK,ROS,MET,PDL1)

Frequently Asked Questions

What is the cost of the Lung Cancer Panel 8 test?
The cost is INR 45000, which includes home sample collection and comprehensive analysis.
What sample is required for this test?
Tumor tissue from a biopsy or surgical resection, typically provided as a paraffin-embedded block or unstained slides.
How long does it take to get results?
Results are usually available within 5-7 days after the sample is received.
Is fasting required before the test?
No, fasting is not required for this test.
Can this test be done at home?
Yes, we offer free home sample collection for online bookings across India.
What genes are analyzed in this panel?
The panel analyzes EGFR, BRAF, ALK, ROS1, MET, and PDL1 expression.
Who should get this test?
Patients diagnosed with non-small cell lung cancer, especially adenocarcinoma, who are candidates for targeted therapy or immunotherapy.
Is a doctor's prescription required?
Yes, a doctor's prescription is required for this test.
What is the difference between this panel and a single gene test?
This panel provides a comprehensive analysis of multiple key biomarkers in one test, saving time and tissue.
Are the results reliable?
Yes, the test is performed using validated methods (FISH, Sanger sequencing, IHC) in NABL-accredited laboratories.
Can this test be done on a blood sample?
No, this test requires tumor tissue. However, a liquid biopsy may be an alternative in some cases.
What if the tumor tissue sample is insufficient?
If the sample is inadequate, the laboratory will inform you, and a re-biopsy may be needed.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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