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Lyme Disease (Borrelia Burgdorferi) IgG & IgM Immunoblot Test

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Lyme Disease (Borrelia Burgdorferi) IgG & IgM Immunoblot Test

Short Name: Lyme Disease IgG & IgM Immunoblot

Also known as: Borrelia burgdorferi IgG IgM Immunoblot, Lyme Antibody Test

Lyme Disease (Borrelia Burgdorferi) IgG & IgM Immunoblot Test test available at DNA Labs India for ₹22,000. Uses Immunoblot on Serum samples. Results in Results are typically available within 2-3 weeks after sample collection.. Free home collection in 300+ cities across India.

Serology🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Kothari Ramesh Shantilal

Dr Kothari Ramesh Shantilal

Consultant Microbiologist · Reg: 27670

Last reviewed: September 7, 2026

Overview

To detect IgG and IgM antibodies against Borrelia burgdorferi for the diagnosis of Lyme disease, aiding in early treatment and prevention of complications.

Test Code
1194
Price
₹22,000
Sample Type
Serum
Result Time
Results are typically available within 2-3 weeks after sample collection.
Fasting Required
No
Method
Immunoblot
Step 1

Sample Collection

Ensure a duly filled Test Send Out Consent Form (Form 35) is available. No fasting required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn via venipuncture from a vein in the arm.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to stop bleeding and avoid strenuous activity.

Timeline: Results are typically available within 2-3 weeks after sample collection.

Patient Instructions

1
Before the Test:No special preparation required, but ensure the consent form is filled and brought to the lab or collection center.
2
During the Test:A simple blood draw procedure that takes a few minutes.
3
After the Test:Resume normal activities immediately. Minor bruising at the puncture site may occur.

About This Test

Who Should Get This Test

To detect IgG and IgM antibodies against Borrelia burgdorferi for the diagnosis of Lyme disease, aiding in early treatment and prevention of complications.

How to Prepare

  • Bring the completed consent form (Form 35)
  • No fasting needed
  • Wear loose-fitting clothing for easy access to the arm
  • Stay hydrated before sample collection

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"Early diagnosis and treatment of Lyme disease are crucial to prevent severe complications. The IgG & IgM immunoblot test provides reliable confirmation of infection."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Insufficient sample volume (<1 mL)
  • Improperly labeled or unlabeled samples
  • Missing consent form

Understanding Your Results

The test measures IgG and IgM antibodies to Borrelia burgdorferi. IgM antibodies typically indicate recent infection, while IgG antibodies suggest past or current infection. Results should be evaluated in conjunction with clinical findings.
IgM positive, IgG negative: Likely recent infection
IgG positive, IgM negative: Possible past infection or late-stage Lyme disease
Both IgM and IgG positive: Active or ongoing infection
Both negative: No serological evidence of infection, but may occur in very early stages
⚠️ When to Consult a Doctor:

Consult an infectious disease specialist immediately if the test is positive, or if symptoms persist despite negative results, especially after tick exposure.

Limitations

  • ⚠May not detect very early infections before antibody development
  • ⚠False positives possible due to cross-reactivity
  • ⚠Results must be interpreted alongside clinical symptoms and history

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare risk of infection or fainting
  • ●No significant risks associated with the test itself

Interfering Factors

  • ●Cross-reactivity with other bacterial infections
  • ●Recent antibiotic therapy
  • ●Immunocompromised conditions
  • ●Vaccination history

Compare With Similar Tests

TestLyme Disease (Borrelia Burgdorferi) IgG & IgM Immunoblot Test
ComparisonLyme Disease (Borrelia Burgdorferi) IgG & IgM Immunoblot Test

Frequently Asked Questions

What is Lyme disease?
Lyme disease is a bacterial infection caused by Borrelia burgdorferi, transmitted through the bite of infected ticks. It can lead to serious health issues if not treated early.
How is the IgG & IgM immunoblot test performed?
The test uses a strip with purified bacterial proteins. Patient blood is incubated with the strip, and antibodies bind to the proteins, detected via a dye to confirm infection.
When should I get tested for Lyme disease?
Testing is recommended if you have symptoms like fever, headache, joint pain, or a rash after a tick bite, or if you live in or visited endemic areas.
What does a positive IgM result mean?
A positive IgM result typically indicates a recent infection with Borrelia burgdorferi, as IgM antibodies are produced early in the immune response.
What does a positive IgG result mean?
A positive IgG result suggests a past or current infection, as IgG antibodies develop later and persist longer in the bloodstream.
Is fasting required for this test?
No, fasting is not required. However, a duly filled Test Send Out Consent Form (Form 35) is mandatory for sample processing.
How accurate is the IgG & IgM immunoblot test?
It is highly accurate and reliable for confirming Lyme disease, especially when used after an initial ELISA screening. False positives are rare but possible.
How long does it take to get the results?
Results are typically available within 2-3 weeks after sample collection, as samples are sent to specialized labs for processing.
Is the test covered by insurance?
Coverage varies by insurance provider and policy. It is advisable to check with your insurance company for specific details.
Where can I get this test done in India?
DNA Labs India offers this test with free home collection in multiple cities across India. You can book online or visit a nearby collection center.
What are the risks of the test?
The test involves a routine blood draw, with minimal risks such as minor bruising or discomfort. Serious complications are extremely rare.
Can this test detect Lyme disease in all stages?
It may not detect very early infections before antibodies develop. For early-stage disease, PCR testing might be recommended in addition to serological tests.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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