Maternal Cell Contamination MCC Test
Short Name: MCC Test
Also known as: MCC Analysis, Maternal Cell Contamination Screening
Maternal Cell Contamination MCC Test test available at DNA Labs India for ₹5,500. Uses STR Analysis, PCR on Blood samples. Results in Reports are typically available within 10 days after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The primary purpose of the MCC test is to verify that a DNA sample collected for genetic analysis is pure and free from maternal cell contamination. This is crucial for prenatal tests like amniocentesis or chorionic villus sampling (CVS), where maternal cells can mix with fetal cells. The test ensures that any genetic result obtained is truly representative of the fetus or neonate, thereby preventing false diagnoses and inappropriate medical decisions.
- Test Code
- 6298
- CPT Code
- 81479
- ICD Code
- Z01.89
- Price
- ₹5,500
- Sample Type
- Blood
- Result Time
- Reports are typically available within 10 days after sample collection.
- Fasting Required
- No
- Method
- STR Analysis, PCR
Sample Collection
No special preparation is required. Inform your doctor if you have had a blood transfusion or bone marrow transplant.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. Apply pressure to the puncture site to prevent bruising.
Timeline: Reports are typically available within 10 days after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the MCC test is to verify that a DNA sample collected for genetic analysis is pure and free from maternal cell contamination. This is crucial for prenatal tests like amniocentesis or chorionic villus sampling (CVS), where maternal cells can mix with fetal cells. The test ensures that any genetic result obtained is truly representative of the fetus or neonate, thereby preventing false diagnoses and inappropriate medical decisions.
How to Prepare
- No fasting required
- Inform the lab if you are pregnant or have recently given birth
- Ensure the sample is collected in the provided EDTA tube
- Keep the sample at room temperature if delivered within 2 hours, otherwise refrigerate
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"MCC testing is crucial for prenatal and postnatal genetic analyses to avoid false results due to maternal cell admixture. It ensures the accuracy of paternity, aneuploidy, and other DNA-based tests."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Clotted sample
- Insufficient volume
- Sample not labeled correctly
- Sample received after prolonged transit time without proper storage
Understanding Your Results
Negative
No maternal cell contamination detected. The sample is suitable for genetic analysis.
Positive
Maternal cell contamination detected. The sample is not suitable for genetic analysis. A new sample should be collected.
If you have undergone prenatal genetic testing and the MCC test is positive, consult your obstetrician or genetic counselor to discuss the need for repeat sampling and the implications for your test results.
Limitations
- ⚠Cannot detect contamination from other individuals (e.g., paternal)
- ⚠May not detect low-level contamination below the detection threshold
- ⚠Requires maternal blood sample for comparison
- ⚠Results may be affected by maternal chimerism or bone marrow transplant
Risks & Considerations
- ●Minimal risk of bruising or bleeding at the puncture site
- ●Rare risk of infection
- ●Fainting or dizziness during blood draw
Interfering Factors
- ●Improper sample collection leading to maternal blood contamination
- ●Hemolyzed or clotted samples
- ●Insufficient sample volume
- ●Contamination during sample processing in the laboratory
Compare With Similar Tests
| Test | Maternal Cell Contamination MCC Test | MCC Test | Fetal DNA Fraction Test | Paternity Test |
|---|---|---|---|---|
| Comparison | Maternal Cell Contamination MCC Test |
Frequently Asked Questions
What is Maternal Cell Contamination (MCC)?
Why is the MCC test important?
Who should undergo the MCC test?
What sample is required for the MCC test?
Is fasting required before the MCC test?
How long does it take to get MCC test results?
What does a positive MCC test result mean?
What does a negative MCC test result mean?
Can the MCC test be done at home?
What is the cost of the MCC test?
Is the MCC test covered by insurance?
Are there any risks associated with the MCC test?
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