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NANOS1 Gene Oligo-astheno-teratozoospermia NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

NANOS1 Gene Oligo-astheno-teratozoospermia NGS Genetic Test

Short Name: NANOS1 OAT NGS Test

Also known as: OAT, Oligoasthenoteratozoospermia

NANOS1 Gene Oligo-astheno-teratozoospermia NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestMaleAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify mutations in the NANOS1 gene associated with oligo-astheno-teratozoospermia, aiding in the diagnosis of genetic male infertility, guiding clinical management, and informing reproductive decisions.

Test Code
5541
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide detailed clinical history and undergo genetic counseling to draw a pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn by a trained phlebotomist using standard venipuncture techniques.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising and keep the area clean.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history and draw a pedigree chart.
2
During the Test:Blood sample collection for DNA extraction and NGS analysis.
3
After the Test:Report generation and follow-up genetic counseling to discuss results and next steps.

About This Test

Who Should Get This Test

To identify mutations in the NANOS1 gene associated with oligo-astheno-teratozoospermia, aiding in the diagnosis of genetic male infertility, guiding clinical management, and informing reproductive decisions.

How to Prepare

  • Bring identification documents and test referral
  • Inform about any medications or health conditions
  • Ensure proper labeling of samples

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for NANOS1 mutations can provide crucial insights into male infertility causes, guiding personalized treatment plans and family counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture

Sample Stability

Blood samples stable at room temperature for 24 hours
Extracted DNA stable for up to 7 days at 4°C
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling or missing information

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the NANOS1 gene, which may explain oligo-astheno-teratozoospermia.
📊

No pathogenic variant detected

Normal NANOS1 gene; OAT may have other genetic or non-genetic causes. Further evaluation recommended.

📊

Pathogenic variant detected

Genetic cause of OAT identified; consult genetic counselor for implications on fertility treatment and family planning.

⚠️ When to Consult a Doctor:

If you experience symptoms of male infertility, have a family history of genetic disorders, or receive abnormal semen analysis results, consult a fertility specialist or geneticist.

Limitations

  • May not detect all genetic variants or epigenetic factors
  • Results require interpretation by a genetic counselor
  • Not a standalone diagnostic tool; clinical correlation needed

Risks & Considerations

  • Minor bruising at puncture site
  • Rare risk of infection
  • Fainting or dizziness during blood draw

Interfering Factors

  • Sample degradation
  • Contamination during collection
  • Technical errors in sequencing

Compare With Similar Tests

TestNANOS1 Gene Oligo-astheno-teratozoospermia NGS Genetic TestSemen AnalysisY-Chromosome Microdeletion TestHormonal Profile TestKaryotyping
ComparisonNANOS1 Gene Oligo-astheno-teratozoospermia NGS Genetic Test

Frequently Asked Questions

What is the NANOS1 Gene OAT NGS Genetic Test?
It is a next-generation sequencing test to detect mutations in the NANOS1 gene associated with oligo-astheno-teratozoospermia, a cause of male infertility.
Who should consider this test?
Men with low sperm count, poor motility, abnormal sperm shape, difficulty conceiving, or a family history of male infertility.
How is the test performed?
A blood sample is collected, DNA is extracted, and NGS technology is used to analyze the NANOS1 gene for mutations.
What is the cost of the test?
The cost is INR 20,000, which includes sample collection, analysis, and report generation.
Is home sample collection available?
Yes, free home sample collection is available across India for online bookings.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What do the results mean?
Results indicate if a pathogenic mutation in the NANOS1 gene is present, which may explain infertility. Genetic counseling is recommended for interpretation.
Is genetic counseling necessary?
Yes, genetic counseling is advised before and after testing to understand implications and guide decisions.
Can this test diagnose all causes of male infertility?
No, it specifically tests for NANOS1 gene mutations. Other genetic or non-genetic factors may require additional tests.
What are the symptoms of OAT?
Symptoms include low sperm count, poor sperm motility, abnormal sperm shape, and difficulty conceiving.
How accurate is the NGS technology?
NGS is highly accurate for detecting genetic variants, but results should be correlated with clinical findings.
What should I do if I have a positive result?
Consult a genetic counselor and fertility specialist to discuss treatment options, such as assisted reproductive technologies.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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