Oncogenic E6/E7 mRNA Test
Short Name: E6/E7 mRNA Test
Also known as: HPV E6/E7 mRNA Test, Oncogenic HPV mRNA Test
Oncogenic E6/E7 mRNA Test test available at DNA Labs India for ₹3,510. Uses Flow Cytometry on Cervical swab / cells samples. Results in Reports available online via portal, email, or WhatsApp within 24-48 hours after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect active oncogenic HPV infection by identifying E6/E7 mRNA expression, aiding in early diagnosis and screening for cervical cancer and high-grade cervical lesions.
- Test Code
- 1355
- Price
- ₹3,510
- Sample Type
- Cervical swab / cells
- Result Time
- Reports available online via portal, email, or WhatsApp within 24-48 hours after sample receipt.
- Fasting Required
- No
- Method
- Flow Cytometry
Sample Collection
No specific preparation required, but avoid vaginal douching, creams, or medications for 48 hours prior to sample collection.
Method: Cervical swab collection
Laboratory Analysis
A healthcare professional will collect a cervical swab or cells using a specialized brush or spatula, placing the sample in a container with transport medium.
Report Delivery
Store the specimen at 2-8°C immediately after collection. Ship refrigerated; do not freeze. Avoid exposure to high temperatures.
Timeline: Reports available online via portal, email, or WhatsApp within 24-48 hours after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To detect active oncogenic HPV infection by identifying E6/E7 mRNA expression, aiding in early diagnosis and screening for cervical cancer and high-grade cervical lesions.
How to Prepare
- Submit cervical swab/cells in the special container with medium provided by LPL.
- Ensure the container is sealed and labeled correctly.
- Ship the sample refrigerated (2-8°C) to the laboratory promptly.
- Do not freeze the specimen.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The detection of HPV E6/E7 mRNA indicates the activity of oncogenic HPV and not just the presence of virus. It improves cervical cancer screening by enhancing specificity for detecting high-grade lesions, offering equivalent clinical sensitivity to HPV DNA tests with better positive predictive value."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Specimen exposed to high temperatures
- Sample collected in incorrect container
- Insufficient sample volume
- Unlabeled or improperly sealed container
Understanding Your Results
Positive
Detectable E6/E7 mRNA suggests active high-risk HPV infection linked to cervical dysplasia or cancer; recommend colposcopy or biopsy for confirmation.
Action: Consult an oncologist or gynecologist for further assessment.
Negative
No detectable E6/E7 mRNA, indicating low likelihood of active oncogenic HPV infection; continue routine screening as advised.
Action: Follow standard cervical cancer screening guidelines; repeat test if symptoms persist.
If you experience symptoms such as abnormal vaginal bleeding, pelvic pain, or unusual discharge, or if you have risk factors like high-risk HPV infection or abnormal Pap results. Consult a healthcare provider promptly for evaluation and potential testing.
Limitations
- ⚠Does not replace histological confirmation via biopsy
- ⚠May not detect all HPV subtypes
- ⚠Results should be interpreted in conjunction with clinical findings and other diagnostic tests
Risks & Considerations
- ●Minimal risk of mild discomfort or spotting after collection
- ●Rare risk of infection if proper aseptic techniques are not followed
Interfering Factors
- ●Exposure of the specimen to high temperatures (adversely affects sample quality)
- ●Improper specimen collection or handling
- ●Contamination during transport
Compare With Similar Tests
| Test | Oncogenic E6/E7 mRNA Test | HPV DNA Test | Pap Test | Cervical Biopsy |
|---|---|---|---|---|
| Comparison | Oncogenic E6/E7 mRNA Test |
Frequently Asked Questions
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