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DNA Labs India

Oncopro 350 Gene TMB & MSI Profile Test

DNA Labs India | ISO 9001:2015 Certified

Oncopro 350 Gene TMB & MSI Profile Test

Short Name: Oncopro 350 TMB MSI Test

Also known as: Oncopro 350 Gene Panel, TMB and MSI Profile Test

Oncopro 350 Gene TMB & MSI Profile Test test available at DNA Labs India for ₹70,200. Uses Next Generation Sequencing on Formalin fixed paraffin embedded (FFPE) tissue block samples. Results in 45 working days from sample receipt. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The primary purpose of the Oncopro 350 Gene TMB & MSI Profile Test is to analyze the genetic mutations in a tumor to predict its response to treatments, particularly immunotherapy. By evaluating Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI), the test helps in risk stratification and identifying patients who may benefit from targeted or immunotherapeutic interventions, thereby guiding personalized cancer management.

Test Code
1366
Price
₹70,200
Sample Type
Formalin fixed paraffin embedded (FFPE) tissue block
Result Time
45 working days from sample receipt
Fasting Required
No
Method
Next Generation Sequencing
Step 1

Sample Collection

Ensure a biopsy is performed and the sample is properly processed into an FFPE block with at least 10% tumor tissue.

Method: Biopsy sample collection

Step 2

Laboratory Analysis

Biopsy procedure should follow standard clinical protocols to obtain representative tumor tissue.

Step 3

Report Delivery

Ship the FFPE tissue block at room temperature to DNA Labs India for analysis.

Timeline: 45 working days from sample receipt

Patient Instructions

1
Before the Test:Consult with your oncologist to determine if this test is appropriate based on your cancer diagnosis and treatment plan.
2
During the Test:The lab processes the FFPE sample using Next Generation Sequencing to analyze the 350-gene panel, TMB, and MSI.
3
After the Test:A detailed report is generated and shared via online portal, email, or WhatsApp, typically within 45 working days.

About This Test

Who Should Get This Test

The primary purpose of the Oncopro 350 Gene TMB & MSI Profile Test is to analyze the genetic mutations in a tumor to predict its response to treatments, particularly immunotherapy. By evaluating Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI), the test helps in risk stratification and identifying patients who may benefit from targeted or immunotherapeutic interventions, thereby guiding personalized cancer management.

How to Prepare

  • Submit formalin fixed paraffin embedded (FFPE) tissue block
  • Block must contain at least 10% tumor tissue
  • Ship at room temperature to maintain sample integrity

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for personalized cancer treatment, helping identify patients who may benefit from immunotherapy based on TMB and MSI status."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeFormalin fixed paraffin embedded (FFPE) tissue block
Sample VolumeAdequate tumor tissue
ContainerFFPE tissue block
Collection MethodBiopsy sample collection

Sample Stability

FFPE blocks are stable at room temperature for extended periods if properly stored
Sample Rejection Criteria:
  • Block with less than 10% tumor tissue
  • Improperly preserved or labeled samples
  • Inadequate sample volume

Understanding Your Results

Results from the Oncopro 350 Gene TMB & MSI Profile Test provide insights into the tumor's genetic alterations, including TMB and MSI status, which are key biomarkers for predicting response to immunotherapy and guiding treatment decisions.
High TMB may indicate a better response to immune checkpoint inhibitors
MSI-High status suggests potential benefit from immunotherapy across various cancer types
Specific gene mutations may guide targeted therapy options
Low TMB or MSS status may imply lower likelihood of immunotherapy benefit
Results should be correlated with clinical history and other diagnostic findings
⚠️ When to Consult a Doctor:

After receiving test results, consult with your oncologist to discuss personalized treatment options based on the genetic profile of your tumor.

Limitations

  • ⚠Test requires adequate tumor tissue content
  • ⚠May not detect all possible genetic variants
  • ⚠Results must be interpreted in clinical context by a specialist
  • ⚠Limited to mutations in the 350-gene panel

Risks & Considerations

  • ●Risks associated with biopsy procedure (e.g., bleeding, infection)
  • ●No direct risks from the genetic test itself
  • ●Potential for psychological impact based on results

Interfering Factors

  • ●Poor sample quality or preservation
  • ●Insufficient tumor tissue in the block (<10%)
  • ●DNA degradation during handling
  • ●Contamination of sample

Compare With Similar Tests

TestOncopro 350 Gene TMB & MSI Profile TestOncopro 500 Gene PanelBRCA1/2 Mutation TestPD-L1 Expression Test
ComparisonOncopro 350 Gene TMB & MSI Profile Test

Frequently Asked Questions

What is the Oncopro 350 Gene TMB & MSI Profile Test?
It is a genetic test that analyzes 350 genes in a tumor to calculate Tumor Mutation Burden (TMB) and Microsatellite Instability (MSI), helping guide cancer treatment, especially immunotherapy.
How is the test performed?
The test is performed on a biopsy sample, typically a formalin-fixed paraffin-embedded (FFPE) tissue block, using Next Generation Sequencing technology to query 1.65 Mb of DNA.
What samples are required for this test?
A formalin-fixed paraffin-embedded (FFPE) tissue block with at least 10% tumor tissue is required, shipped at room temperature.
How long does it take to get the results?
Results are typically available within 45 working days from sample receipt, and reports are delivered via online portal, email, or WhatsApp.
What is Tumor Mutation Burden (TMB)?
TMB measures the number of mutations in a tumor's DNA. High TMB may indicate a better response to immunotherapy.
What is Microsatellite Instability (MSI)?
MSI is a condition reflecting defects in DNA repair. MSI-High tumors are often more responsive to immunotherapy.
How does this test help in cancer treatment?
By identifying genetic mutations, TMB, and MSI status, the test helps oncologists choose targeted therapies or immunotherapy, personalizing treatment for better outcomes.
Is the test covered by insurance?
Coverage varies by insurance plan. It is recommended to check with your provider, as the test may not be covered under schemes like PMJAY or CGHS.
What is the cost of the test?
The cost at DNA Labs India is INR 70200, which includes test, sample collection, and processing fees.
Where can I get this test done?
DNA Labs India offers home sample collection in numerous cities across India, including Mumbai, Delhi, Bangalore, and more. Book online for convenience.
What are the risks associated with the test?
Risks are minimal and mainly related to the biopsy procedure, such as bleeding or infection. The genetic test itself poses no direct risks.
How should I prepare for the test?
No special preparation is needed, but ensure your biopsy sample is properly collected and preserved as an FFPE block with adequate tumor tissue before shipping.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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