PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test
Short Name: PALB2 Gene Test
Also known as: PALB2 Gene Mutation Test, Pancreatic Cancer Genetic Susceptibility Test
PALB2 Gene Pancreatic cancer type 3, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the PALB2 gene that increase susceptibility to pancreatic cancer type 3, enabling early risk assessment, genetic counseling, and personalized medical management to improve outcomes.
- Test Code
- 2918
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and undergo genetic counseling as per pre-test information.
Method: Venipuncture or finger-prick
Laboratory Analysis
A blood sample will be collected via venipuncture or finger-prick. For FTA card, a single drop of blood is applied.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store sample as instructed for stability.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the PALB2 gene that increase susceptibility to pancreatic cancer type 3, enabling early risk assessment, genetic counseling, and personalized medical management to improve outcomes.
How to Prepare
- Ensure patient identification and consent
- Use sterile equipment for blood collection
- Label samples correctly with patient details
- Transport samples at ambient room temperature to the lab
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This test is crucial for individuals with a family history of pancreatic cancer or related symptoms to assess genetic risk and guide early intervention strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Positive for PALB2 mutation
Increased susceptibility to pancreatic cancer type 3. Recommend enhanced screening, genetic counseling, and consultation with an oncologist for personalized management.
Negative for PALB2 mutation
No pathogenic variant detected in the PALB2 gene. Risk may be lower, but clinical correlation and family history should be considered. Continue standard screening if indicated.
Variant of uncertain significance (VUS)
Genetic variant detected but clinical significance unknown. Recommend periodic re-evaluation and genetic counseling for updated guidance.
Consult a doctor if you have a family history of pancreatic cancer, experience symptoms like jaundice or weight loss, or receive a positive test result for further evaluation and management.
Limitations
- ⚠Does not detect all genetic variants or mutations in other genes
- ⚠Results may not predict cancer onset with certainty due to environmental factors
- ⚠Limited to PALB2 gene; other pancreatic cancer susceptibility genes not covered
Risks & Considerations
- ●Minimal risks from blood draw, such as bruising or infection
- ●Psychological impact of genetic risk information
- ●Potential for false positives or negatives, though rare with NGS
Interfering Factors
- ●Sample contamination or degradation
- ●Recent blood transfusions may affect DNA analysis
- ●Inadequate sample volume or improper storage
Frequently Asked Questions
What is the PALB2 gene?
How is the PALB2 gene linked to pancreatic cancer type 3?
Who should consider taking this genetic test?
How is the NGS genetic test performed?
What does a positive test result mean?
What are the symptoms of pancreatic cancer type 3?
Is the test covered by insurance?
What is the cost of the PALB2 gene test?
How long does it take to get the test results?
What preparation is needed before the test?
Are there any risks associated with the test?
What should I do after receiving the test results?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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