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DNA Labs India

PDGFR? (HES) Test

DNA Labs India | ISO 9001:2015 Certified

PDGFR? (HES) Test

Short Name: PDGFRα (HES)

Also known as: PDGFRα Mutation Test, Hypereosinophilic Syndrome Genetic Test

PDGFR? (HES) Test test available at DNA Labs India for ₹5,250. Uses FISH on Bone Marrow / Peripheral blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.

Genetic🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the PDGFRα (HES) test is to detect mutations in the PDGFRα gene to confirm a diagnosis of hypereosinophilic syndrome (HES). This helps in guiding targeted treatment strategies and monitoring disease progression.

Test Code
3141
Price
₹5,250
Sample Type
Bone Marrow / Peripheral blood
Result Time
3-4 days
Fasting Required
No
Method
FISH
Step 1

Sample Collection

A doctor's prescription is required. Inform the lab about any medications or recent procedures.

Method: Blood draw or bone marrow aspiration

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein or bone marrow aspirated under sterile conditions.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bleeding. Resume normal activities unless advised otherwise.

Timeline: 3-4 days

Patient Instructions

1
Before the Test:Obtain a doctor's prescription. No fasting is required unless specified by the physician.
2
During the Test:Sample collection takes about 15-30 minutes. It may involve a blood draw or bone marrow aspiration.
3
After the Test:Mild soreness at the collection site is normal. Results will be available in 3-4 days.

About This Test

Who Should Get This Test

The purpose of the PDGFRα (HES) test is to detect mutations in the PDGFRα gene to confirm a diagnosis of hypereosinophilic syndrome (HES). This helps in guiding targeted treatment strategies and monitoring disease progression.

How to Prepare

  • Ensure a valid prescription is available.
  • Avoid strenuous activity before sample collection.
  • Follow any specific instructions from the healthcare provider.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The PDGFRα (HES) test is essential for confirming hypereosinophilic syndrome, enabling targeted therapy and improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBone Marrow / Peripheral blood
ContainerSodium Heparin Vacutainer (2ml)
Collection MethodBlood draw or bone marrow aspiration

Sample Stability

Blood samples should be processed within 24 hours at ambient temperature.
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Samples without proper labeling or documentation

Understanding Your Results

Results indicate the presence or absence of PDGFRα mutations. A positive result confirms HES, while a negative result may require further testing.
📊

Positive

PDGFRα mutation detected, confirming hypereosinophilic syndrome. Consult an oncologist for treatment options.

📊

Negative

No PDGFRα mutation detected. Clinical correlation and additional tests may be needed to rule out HES.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like persistent fever, fatigue, or swelling, or if test results are abnormal.

Limitations

  • Test only detects PDGFRα mutations; other genetic causes of HES may not be identified.
  • Results should be correlated with clinical findings and other diagnostic tests.

Risks & Considerations

  • Minor bruising or pain at the collection site
  • Rare risk of infection with bone marrow aspiration

Interfering Factors

  • Sample contamination
  • Improper sample storage
  • Recent blood transfusions may affect results

Frequently Asked Questions

What is the PDGFR? (HES) test?
It is a genetic test that detects mutations in the PDGFR? gene to diagnose hypereosinophilic syndrome (HES), a rare leukemia.
Why is this test recommended?
It is recommended for individuals with symptoms of HES, such as persistent fever, fatigue, or swelling, to confirm the diagnosis.
How is the test performed?
A blood or bone marrow sample is collected and analyzed using FISH (Fluorescence In Situ Hybridization) to identify PDGFR? mutations.
What is the cost of the PDGFR? (HES) test in India?
The cost is approximately INR 5250, but it may vary by laboratory. DNA Labs India offers it at a discounted price with free home collection.
Is fasting required for this test?
No, fasting is not typically required. However, follow any specific instructions from your doctor.
How long does it take to get results?
Results are usually available within 3-4 days after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What do positive results mean?
A positive result indicates the presence of a PDGFR? mutation, confirming hypereosinophilic syndrome. Consult an oncologist for treatment.
What if the test is negative?
A negative result means no PDGFR? mutation was detected. Further clinical evaluation and tests may be needed to diagnose HES.
Is the test covered by insurance?
Many insurance companies may cover genetic testing, but coverage varies. Check with your provider for details.
Are there any risks associated with the test?
Risks are minimal and may include minor bruising or pain at the sample collection site.
How accurate is the PDGFR? (HES) test?
The test is highly accurate for detecting PDGFR? mutations, but results should be interpreted in conjunction with clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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