PMS1 Gene Nonpolyposis hereditary colon cancer, PMS1 related NGS Genetic Test
Short Name: PMS1 Gene Test
Also known as: PMS1-related Hereditary Colon Cancer Test, PMS1 Gene Mutation Analysis, Hereditary Colon Cancer NGS Test
PMS1 Gene Nonpolyposis hereditary colon cancer, PMS1 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the PMS1 gene associated with hereditary nonpolyposis colon cancer (HNPCC). It aids in confirming diagnosis, assessing cancer risk, guiding surveillance strategies, and informing family planning decisions.
- Test Code
- 2915
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- Yes (8 hours)
- Method
- NGS Technology
Sample Collection
Ensure genetic counseling is completed and clinical history is documented. No specific dietary restrictions, but fasting for 8 hours may be required for optimal sample quality.
Method: Venipuncture or FTA Card Spot
Laboratory Analysis
A blood sample will be drawn via venipuncture or a drop of blood placed on an FTA card. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately. Store the sample as per instructions if self-collected.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the PMS1 gene associated with hereditary nonpolyposis colon cancer (HNPCC). It aids in confirming diagnosis, assessing cancer risk, guiding surveillance strategies, and informing family planning decisions.
How to Prepare
- Fast for 8 hours before blood draw if required
- Use sterile equipment for sample collection
- Label samples correctly with patient details
- Transport samples at ambient temperature unless specified otherwise
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for early detection and management of hereditary colon cancer, especially in individuals with a family history or symptoms suggestive of PMS1 gene mutations."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Contaminated or hemolyzed samples
- Incorrect labeling or missing patient information
- Samples not stored or transported as per guidelines
Understanding Your Results
Consult a doctor if you have a family history of colon cancer, experience symptoms like blood in stool or unexplained weight loss, or receive a positive genetic test result for further management and screening.
Limitations
- ⚠May not detect all types of PMS1 gene mutations, such as large deletions or deep intronic variants
- ⚠Results require correlation with clinical and family history for accurate interpretation
- ⚠Does not rule out other genetic causes of hereditary colon cancer
Risks & Considerations
- ●Minimal risk from blood draw, such as slight pain, bruising, or infection at the puncture site
- ●Psychological impact from genetic results; counseling is recommended
Interfering Factors
- ●Contaminated or degraded DNA samples
- ●Recent blood transfusions affecting DNA analysis
- ●Technical errors in sample collection or processing
Compare With Similar Tests
| Test | PMS1 Gene Nonpolyposis hereditary colon cancer, PMS1 related NGS Genetic Test | MLH1 Gene Test | MSH2 Gene Test | MSH6 Gene Test | Comprehensive Lynch Syndrome Panel |
|---|---|---|---|---|---|
| Comparison | PMS1 Gene Nonpolyposis hereditary colon cancer, PMS1 related NGS Genetic Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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