Purkinje Cell Cytoplasmic Antibody Type Tr (DNER) Test
Short Name: Pyruvate Test
Also known as: Pyruvate Test, Pyruvic Acid Test, Lactate/Pyruvate Ratio
Purkinje Cell Cytoplasmic Antibody Type Tr (DNER) Test test available at DNA Labs India for ₹4,500. Uses Spectrophotometry on Whole blood samples. Results in Reports are available the same day if the sample is submitted by 2 pm.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Pyruvate Pyruvic Acid Test is to measure the concentration of pyruvate in the blood, which is crucial for evaluating the body's energy metabolism. It helps identify whether the body is appropriately breaking down glucose for energy and is particularly useful in diagnosing mitochondrial disorders, pyruvate dehydrogenase deficiency, and other metabolic conditions. This test is often performed with a lactate test to calculate the lactate-to-pyruvate ratio.
- Test Code
- 3586
- Price
- ₹4,500
- Sample Type
- Whole blood
- Result Time
- Reports are available the same day if the sample is submitted by 2 pm.
- Fasting Required
- No
- Method
- Spectrophotometry
Sample Collection
No special preparation is required. Inform your doctor about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A small blood sample is drawn from a vein in your arm. The blood is immediately mixed with perchloric acid to stabilise it.
Report Delivery
You can resume normal activities immediately. The sample will be processed in the laboratory.
Timeline: Reports are available the same day if the sample is submitted by 2 pm.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Pyruvate Pyruvic Acid Test is to measure the concentration of pyruvate in the blood, which is crucial for evaluating the body's energy metabolism. It helps identify whether the body is appropriately breaking down glucose for energy and is particularly useful in diagnosing mitochondrial disorders, pyruvate dehydrogenase deficiency, and other metabolic conditions. This test is often performed with a lactate test to calculate the lactate-to-pyruvate ratio.
How to Prepare
- Collect 3 mL (2 mL min) whole blood in a Grey Top (Sodium Fluoride) tube.
- Mix whole blood immediately with an equal volume of 7% Perchloric Acid.
- Mix well and centrifuge immediately.
- Separate the supernatant and submit a minimum of 2 mL.
- Ship the sample refrigerated or frozen.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Pyruvate testing is often essential in evaluating children with suspected metabolic myopathies or encephalopathies. It should be combined with lactate measurement for accurate interpretation."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Clotted sample
- Sample not mixed with perchloric acid
- Delayed centrifugation
- Hemolyzed specimen
- Insufficient sample volume
Understanding Your Results
High lactate-to-pyruvate ratio (>20) suggests a defect in the electron transport chain or pyruvate carboxylase deficiency.
Normal ratio may suggest pyruvate dehydrogenase deficiency or disorders of pyruvate metabolism.
Significant mitochondrial/metabolic disease is less likely.
If you are experiencing unexplained fatigue, muscle weakness, seizures, developmental delays, or any neurological symptoms, consult a physician. A doctor can determine whether a pyruvate test is suitable for you and help interpret the results.
Limitations
- ⚠A single pyruvate level is not diagnostic and should be interpreted in the context of lactate and clinical findings.
- ⚠Strict preanalytical conditions are necessary; otherwise, results may be falsely elevated or depressed.
Risks & Considerations
- ●Slight pain or bruising at the injection site
- ●Dizziness
- ●Rare risk of infection
Interfering Factors
- ●Hemolysis of the blood sample
- ●Delayed handling of the sample
- ●Failure to immediately mix with perchloric acid
- ●Prolonged tourniquet application
- ●Recent exercise before blood collection
Compare With Similar Tests
| Test | Purkinje Cell Cytoplasmic Antibody Type Tr (DNER) Test | Lactate Test | Lactate/Pyruvate Ratio |
|---|---|---|---|
| Comparison | Purkinje Cell Cytoplasmic Antibody Type Tr (DNER) Test |
Frequently Asked Questions
What is the Pyruvate Pyruvic Acid Test?
Why is this test important?
What are the symptoms of pyruvate disorders?
How is the test done?
Do I need to fast before the test?
What is the cost of the test at DNA Labs India?
How long will it take to get the results?
What is the lactate to pyruvate ratio?
Are there any risks with the test?
Is home sample collection available?
Where is this test available?
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