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DNA Labs India

Rheumatoid Arthritis Panel Test

DNA Labs India | ISO 9001:2015 Certified

Rheumatoid Arthritis Panel Test

Short Name: RA Panel

Also known as: RA Panel, Rheumatoid Arthritis Profile, RA Autoantibody Panel, RF + Anti-CCP + ANA Panel

Rheumatoid Arthritis Panel Test test available at DNA Labs India for ₹4,500. Uses Enzyme Immunoassay (EIA), Immunoturbidimetry, Chemiluminescent Microparticle Immunoassay (CMIA) on Serum samples. Results in Reports are generally available the same day, usually within 6-8 hours after sample collection.. Free home collection in 300+ cities across India.

Blood TestAll Ages🏠 Home Collection

Overview

The purpose of the Rheumatoid Arthritis Panel is to detect and measure antibodies and inflammatory markers that aid in the diagnosis of rheumatoid arthritis and help differentiate it from other autoimmune or inflammatory joint diseases. The panel combines three serological tests: ANA, RF, and anti-CCP, providing a broader diagnostic picture. It is particularly useful when clinical signs such as symmetric joint pain, morning stiffness, and swelling are present. The results help clinicians establish an early diagnosis, assess prognosis, and guide therapeutic decisions.

Test Code
3604
ICD Code
M06.9
Price
₹4,500
Sample Type
Serum
Result Time
Reports are generally available the same day, usually within 6-8 hours after sample collection.
Fasting Required
No
Method
Enzyme Immunoassay (EIA), Immunoturbidimetry, Chemiluminescent Microparticle Immunoassay (CMIA)
Step 1

Sample Collection

No special preparation required. However, it is advisable to inform your doctor about all medications you are taking, as some drugs may affect the test results.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is drawn from a vein in your arm. A tourniquet is applied briefly to make veins more visible; a small needle is inserted, and the required blood is collected in an SST.

Step 3

Report Delivery

You may resume normal activities immediately. Pressure is applied at the site to stop bleeding. Keep the dressing on for a few hours. Drink plenty of fluids.

Timeline: Reports are generally available the same day, usually within 6-8 hours after sample collection.

Patient Instructions

1
Before the Test:No special preparation required. Inform your doctor if you are taking immunosuppressants or biologic agents.
2
During the Test:Blood is drawn from a vein in the arm. The procedure is quick and causes only minor discomfort.
3
After the Test:No restrictions. You can return to normal activities immediately.

About This Test

Who Should Get This Test

The purpose of the Rheumatoid Arthritis Panel is to detect and measure antibodies and inflammatory markers that aid in the diagnosis of rheumatoid arthritis and help differentiate it from other autoimmune or inflammatory joint diseases. The panel combines three serological tests: ANA, RF, and anti-CCP, providing a broader diagnostic picture. It is particularly useful when clinical signs such as symmetric joint pain, morning stiffness, and swelling are present. The results help clinicians establish an early diagnosis, assess prognosis, and guide therapeutic decisions.

How to Prepare

  • Patient should be seated comfortably during collection
  • Tourniquet should be applied for less than 1 minute
  • Blood should be collected into SST
  • Sample should be shipped refrigerated or frozen after processing

Doctor's Notes

"Early detection using a combination of RF, anti-CCP, and ANA can make a significant difference in slowing RA progression. The panel is a one-stop serological evaluation for patients with suspected inflammatory arthritis."

Test Parameters & Specifications

Sample TypeSerum
Sample Volume3 mL (1.5 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 2 hours
Refrigerated (2-8°C): 1 week
Frozen (-20°C): 4 weeks
Sample Rejection Criteria:
  • Hemolyzed, lipemic, or icteric samples may be rejected
  • Improper labeling or missing patient identification
  • Clotted sample when serum is specifically required

Understanding Your Results

The Rheumatoid Arthritis Panel helps detect the presence of autoantibodies commonly associated with RA. Interpretation should be done by a specialist in the context of clinical history and physical examination.
📊

RF +, Anti-CCP +, ANA +

Strongly suggestive of Rheumatoid Arthritis. Clinical correlation and imaging recommended.

📊

RF +, Anti-CCP -

Suggests possible RA; anti-CCP negative RA can occur. Further testing and clinical assessment needed.

📊

RF -, Anti-CCP +

High specificity for RA; may indicate early stages or seronegative RA. Clinical evaluation advised.

📊

ANA + with RF and Anti-CCP negative

May suggest a systemic autoimmune disease other than RA; further workup recommended.

📊

All parameters negative

RA is less likely; however, seronegative RA is possible. Repeat or additional tests if clinical suspicion remains high.

⚠️ When to Consult a Doctor:

If you experience joint pain, swelling, stiffness lasting more than 6 weeks, fatigue, or unexplained fever, consult a rheumatologist or physician.

Limitations

  • A positive RF is not diagnostic of RA alone; it can be positive in other autoimmune and infectious diseases
  • A negative Anti-CCP does not rule out RA; some patients are seronegative
  • Results must be interpreted in conjunction with clinical findings and imaging
  • This panel does not include other inflammatory markers such as ESR or CRP, which may be useful for monitoring disease activity

Risks & Considerations

  • Bruising or soreness at the needle site
  • Dizziness or fainting
  • Infection (rare)
  • Excessive bleeding (rare, in patients with bleeding disorders)

Interfering Factors

  • Medications such as corticosteroids and methotrexate may suppress antibody levels
  • Recent infections or vaccinations may cause false-positive ANA
  • Sample hemolysis or lipemia may affect immunoturbidimetric readings
  • Biologic agents used in RA treatment can interfere with RF measurement
  • Improper storage of the serum sample may lead to inaccurate results

Compare With Similar Tests

TestRheumatoid Arthritis Panel TestRheumatoid Factor (RF) OnlyAnti-CCP OnlyAntinuclear Antibody (ANA)Erythrocyte Sedimentation Rate (ESR)C-Reactive Protein (CRP)
ComparisonRheumatoid Arthritis Panel Test

Frequently Asked Questions

What is the Rheumatoid Arthritis Panel test?
The Rheumatoid Arthritis Panel is a blood test that measures several autoantibodies and markers associated with rheumatoid arthritis (RA), including ANA, RF, and anti-CCP. It helps confirm a diagnosis of RA and differentiate it from other autoimmune disorders.
What is the cost of the RA Panel test?
The cost of the Rheumatoid Arthritis Panel test at DNA Labs India is Rs 4500. This includes the panel parameters and a digital report. We also offer free home sample collection for online bookings.
Is fasting required for the RA Panel?
No, fasting is not required for the Rheumatoid Arthritis Panel test. You can eat and drink normally before the test.
How is the test performed?
The test is performed by drawing a small blood sample from a vein in your arm into a Serum Separator Tube (SST). The sample is then transported to the laboratory and analyzed using standardized immunology methods.
What are the risks of the test?
The test is very safe. Minor risks include slight bruising or soreness at the needle site, dizziness, and very rarely infection or prolonged bleeding.
How long does it take to get results?
Reports are typically available the same day, usually within 6-8 hours after sample collection. You will receive the report via email, WhatsApp, or an online portal.
Which markers are included in the panel?
The panel includes Antinuclear Antibody (ANA), Rheumatoid Factor (RF), and Anti-Cyclic Citrullinated Peptide (Anti-CCP) antibodies. These markers are the core serological tests used to evaluate rheumatoid arthritis.
Can the test be done during pregnancy?
Yes, the RA Panel can be done during pregnancy if clinically indicated. However, pregnancy can affect autoimmune markers, so results should be interpreted by a doctor familiar with pregnancy-related changes.
What does a positive ANA mean?
A positive ANA indicates the presence of antinuclear antibodies, which may suggest an autoimmune condition such as RA, systemic lupus erythematosus (SLE), or other connective tissue diseases. It is not specific for RA and requires further evaluation.
How often should the test be repeated?
For monitoring confirmed RA, the panel may be repeated every 3-6 months based on disease activity. For initial diagnosis, a single test is usually sufficient, but a doctor may recommend repeating if symptoms persist and initial results are negative.
Does the test require any special preparation?
No special preparation is required. However, you should inform your doctor about any medications you are taking, as certain drugs like methotrexate, biologics, or corticosteroids can influence antibody levels.
Are home sample collection services available?
Yes, DNA Labs India provides free home sample collection for the Rheumatoid Arthritis Panel test in over 200 cities across India. Collection is performed by trained phlebotomists with proper safety protocols.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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