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Rheumatoid Autoimmune Panel Test

DNA Labs India | ISO 9001:2015 Certified

Rheumatoid Autoimmune Panel Test

Short Name: Rheumatoid Autoimmune Panel

Also known as: Rheumatoid Autoimmune Panel

Rheumatoid Autoimmune Panel Test test available at DNA Labs India for ₹13,000. Uses Enzyme Immunoassay, Immunoturbidimetry on Serum samples. Results in Same-day report for samples received by 9 am on Tuesday or Friday. Reports are delivered through online portal, email, and WhatsApp.. Free home collection in 300+ cities across India.

Autoimmune Serology Panel🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of this panel is to analyze serum for ANA and other autoantibodies associated with systemic rheumatic diseases, along with complement C3 and C4. Measuring these markers helps clinicians evaluate the likelihood of an autoimmune process, monitor disease activity, and assess treatment response when interpreted with clinical findings.

Test Code
3605
Price
₹13,000
Sample Type
Serum
Result Time
Same-day report for samples received by 9 am on Tuesday or Friday. Reports are delivered through online portal, email, and WhatsApp.
Fasting Required
No
Method
Enzyme Immunoassay, Immunoturbidimetry
Step 1

Sample Collection

Overnight fasting is preferred. Inform your doctor about all current medications, especially disease-modifying anti-rheumatic drugs (DMARDs), steroids, or immunosuppressants.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be collected from a vein in your arm by a trained phlebotomist. The procedure usually takes only a few minutes.

Step 3

Report Delivery

After the sample is collected, a cotton pad and bandage will be applied over the puncture site. You may resume normal activities and your normal diet unless advised otherwise.

Timeline: Same-day report for samples received by 9 am on Tuesday or Friday. Reports are delivered through online portal, email, and WhatsApp.

Patient Instructions

1
Before the Test:Overnight fasting is preferred. Inform your doctor about all medications, supplements, and recent infections.
2
During the Test:A blood sample will be drawn from a vein in your arm using a sterile needle. The procedure is quick and usually well tolerated.
3
After the Test:You may leave immediately after the sample collection. Mild bruising or soreness at the puncture site can occur and usually resolves quickly.

About This Test

Who Should Get This Test

The purpose of this panel is to analyze serum for ANA and other autoantibodies associated with systemic rheumatic diseases, along with complement C3 and C4. Measuring these markers helps clinicians evaluate the likelihood of an autoimmune process, monitor disease activity, and assess treatment response when interpreted with clinical findings.

How to Prepare

  • Overnight fasting is preferred but not strictly mandatory
  • Inform your doctor about current medications, especially immunosuppressants or steroids
  • Bring your doctor's prescription and previous lab reports, if available
  • Keep yourself well hydrated unless otherwise advised

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"A comprehensive autoimmune panel can reduce diagnostic delay when symptoms are subtle, but positive autoantibodies alone do not establish a diagnosis. Clinical correlation by a rheumatologist or immunologist remains essential."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume6 mL (4 mL minimum)
Container2 Serum Separator Tubes (SST)
Collection MethodVenipuncture

Sample Stability

Room temperature2 hours
Refrigerated1 week
Frozen4 weeks
Sample Rejection Criteria:
  • Haemolysed or visibly lipemic samples
  • Clotted samples collected in SST without proper mixing
  • Sample volume less than 4 mL
  • Incorrectly labelled sample or missing patient identification
  • Sample stored under improper temperature conditions

Understanding Your Results

Interpretation requires clinical correlation. This panel is not diagnostic by itself and should be reviewed by a qualified physician.
Positive ANA is reported with titer and pattern; it is sensitive for SLE but can also be seen in other autoimmune and even healthy individuals.
Positive anti-dsDNA has high specificity for systemic lupus erythematosus in the appropriate clinical context.
Positive anti-Sm is a specific marker for systemic lupus erythematosus.
Positive anti-U1RNP is associated with mixed connective tissue disease.
Positive anti-SS-A/Ro and anti-SS-B/La are associated with Sjögren's syndrome.
Positive anti-centromere antibody is associated with limited cutaneous systemic sclerosis/CREST syndrome.
Rheumatoid factor can be positive in rheumatoid arthritis, other autoimmune diseases, infections, and chronic inflammatory conditions.
Low C3 and/or C4 may indicate complement consumption and immune complex activity.
⚠️ When to Consult a Doctor:

If you have persistent joint pain, stiffness, fatigue, unexplained fever, skin rashes, or other systemic symptoms, consult a rheumatologist or physician. Abnormal test results should always be discussed with a doctor.

Limitations

  • ⚠This panel is not diagnostic by itself and requires clinical correlation
  • ⚠ANA can be positive in healthy individuals, especially with increasing age
  • ⚠Negative serology does not exclude autoimmune disease
  • ⚠Reference ranges and methods may vary between laboratories

Risks & Considerations

  • ●Bruising at the injection site
  • ●Bleeding from the puncture site
  • ●Haematoma
  • ●Infection (rare)
  • ●Dizziness or lightheadedness

Interfering Factors

  • ●Haemolysis or lipemia may interfere with complement immunoassays
  • ●Recent infections can cause transient autoantibody positivity
  • ●Certain medications, especially immunosuppressants and steroids, may affect autoantibody levels
  • ●Sample contamination or improper storage can alter results

Compare With Similar Tests

TestRheumatoid Autoimmune Panel Test
ComparisonRheumatoid Autoimmune Panel Test

Frequently Asked Questions

What is the cost of the Rheumatoid Autoimmune Comprehensive Panel Test?
The test costs Rs 13000.0 at DNA Labs India. Free home sample collection is included for online bookings in many cities across India.
Is fasting required before the test?
Overnight fasting is preferred but not strictly mandatory. Follow the instructions given by the laboratory or your doctor before the sample is collected.
Which parameters are included in this panel?
The panel includes ANA, anti-dsDNA, anti-Sm, anti-U1RNP, rheumatoid factor, complement C3, complement C4, anti-SS-A/Ro, anti-SS-B/La, and centromere antibody.
How is the sample collected?
A trained phlebotomist collects about 6 mL of blood from a vein, usually from the arm, into serum separator tubes.
When will I get the report?
For samples received by 9 am on Tuesday or Friday, reports are available on the same day. Delivery is through online portal, email, and WhatsApp.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings for this test in multiple cities across India.
What diseases can this test help detect?
It supports evaluation of rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, mixed connective tissue disease, scleroderma/CREST syndrome, and other autoimmune rheumatic conditions.
Do I need a doctor's prescription for this test?
It is recommended that the test be ordered by a rheumatologist or treating physician so that results are interpreted in the correct clinical context.
Can this test definitively confirm an autoimmune disease?
No single autoantibody or panel can by itself confirm an autoimmune disease. Results must be interpreted along with symptoms, physical examination, and other investigations.
What does a positive ANA mean?
A positive ANA means the test detected antinuclear antibodies. It can occur in autoimmune diseases but may also be found in healthy individuals; further antibody testing is usually needed.
Is this test covered by health insurance?
Coverage depends on the insurance provider and policy. You should check with your insurer and the laboratory for pre-authorization and claim processes.
How can I book this test at DNA Labs India?
You can book online through the DNA Labs India website. Once booked, free home sample collection will be arranged at your preferred address and time.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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