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Rheumatoid Factor IgA Test

DNA Labs India | ISO 9001:2015 Certified

Rheumatoid Factor IgA Test

Short Name: RF IgA

Also known as: IgA Rheumatoid Factor, Rheumatoid Factor IgA Antibody Test

Rheumatoid Factor IgA Test test available at DNA Labs India for ₹983. Uses Enzyme Immunoassay on Serum samples. Results in Samples submitted by 9 am are usually reported on the same day. Deliverables are available via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

Blood test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of the Rheumatoid Factor IgA test is to detect the presence of IgA class autoantibodies that are often elevated in rheumatoid arthritis and other autoimmune conditions. This test aids in the diagnosis of rheumatoid arthritis, helps assess the likelihood of disease progression, and serves as a prognostic marker for severe joint damage. It is particularly useful in the early phase of polyarthritis when clinical symptoms may be ambiguous. It may also be ordered to evaluate patients with unexplained synovitis or to differentiate seropositive from seronegative RA.

Test Code
3602
Price
₹983
Sample Type
Serum
Result Time
Samples submitted by 9 am are usually reported on the same day. Deliverables are available via online portal, email, or WhatsApp.
Fasting Required
No
Method
Enzyme Immunoassay
Step 1

Sample Collection

No special preparation is required. Inform your doctor about any current medications or supplements. You may eat and drink normally before the test.

Method: Venipuncture

Step 2

Laboratory Analysis

A trained phlebotomist will draw a small blood sample from a vein in your arm. The procedure takes about 5 minutes and is generally well tolerated.

Step 3

Report Delivery

After the blood sample is drawn, you can resume normal activities immediately. Keep the puncture site clean and apply pressure if there is any slight bleeding.

Timeline: Samples submitted by 9 am are usually reported on the same day. Deliverables are available via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:No special preparation is required for the Rheumatoid Factor IgA test. You can take it at any time of the day.
2
During the Test:A blood sample will be collected from your arm using a sterile needle. Mild discomfort may be felt, but it is quick and safe.
3
After the Test:You can immediately resume daily activities. No post-test restrictions are necessary.

About This Test

Who Should Get This Test

The purpose of the Rheumatoid Factor IgA test is to detect the presence of IgA class autoantibodies that are often elevated in rheumatoid arthritis and other autoimmune conditions. This test aids in the diagnosis of rheumatoid arthritis, helps assess the likelihood of disease progression, and serves as a prognostic marker for severe joint damage. It is particularly useful in the early phase of polyarthritis when clinical symptoms may be ambiguous. It may also be ordered to evaluate patients with unexplained synovitis or to differentiate seropositive from seronegative RA.

How to Prepare

  • Use a serum separator tube (SST) to collect at least 2 mL of venous blood.
  • Home sample collection is available; trained professionals follow strict safety protocols.
  • Label the tube with patient ID and date of collection.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Rheumatoid Factor IgA is a valuable marker in the early diagnosis of rheumatoid arthritis. A positive result should always be interpreted alongside clinical findings and other serological tests like anti-CCP."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
Container1 SST (serum separator tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 2 hours
Refrigerated (2-8°C): 1 week
Frozen (-20°C): 4 weeks
Sample Rejection Criteria:
  • Hemolyzed, icteric, or lipemic specimens are rejected
  • Improperly labelled samples are not accepted
  • Samples older than the recommended stability period are rejected

Understanding Your Results

The Rheumatoid Factor IgA test result should be interpreted by a qualified clinician in the context of the patient's clinical presentation. Immunoassay results are semi-quantitative and expressed in units per milliliter.
📊

Negative RF IgA (< 20 U/mL)

RA is less likely but not completely excluded, especially in early disease. Clinical correlation and anti-CCP antibody testing may be helpful.

📊

Positive RF IgA (≥ 20 U/mL)

Elevated IgA RF suggests a higher probability of rheumatoid arthritis and may indicate a more aggressive disease course. Further evaluation with anti-CCP, ESR, CRP, and imaging is recommended.

📊

Borderline result

Results near the cut-off should be repeated in 4-6 weeks or correlated with other laboratory and clinical data.

⚠️ When to Consult a Doctor:

If you are experiencing persistent joint pain, swelling, stiffness, and fatigue lasting for more than six weeks, it is advisable to consult a rheumatologist. Early referral and diagnosis can help initiate disease-modifying therapy and prevent irreversible joint damage.

Limitations

  • ⚠A negative RF IgA test does not exclude rheumatoid arthritis; a significant proportion of RA patients are seronegative
  • ⚠IgA RF can be elevated in other autoimmune rheumatic diseases, chronic liver disease, and some infections
  • ⚠Test results should always be correlated with clinical symptoms and other biomarkers like anti-CCP
  • ⚠Reference ranges may differ between laboratories, so serial testing should ideally be done at the same lab

Risks & Considerations

  • ●Minimal: slight pain or bruising at the puncture site
  • ●Rare: dizziness or lightheadedness during blood draw
  • ●Very rare: infection at the needle insertion site

Interfering Factors

  • ●Recent infection or vaccination may cause transient autoantibody production
  • ●Lipemic, hemolyzed, or icteric samples can affect assay accuracy
  • ●Presence of circulating immune complexes may interfere with immunoassay
  • ●High levels of immunoglobulins from other conditions may produce false-positive results

Compare With Similar Tests

TestRheumatoid Factor IgA TestRheumatoid Factor IgGAnti-CCP AntibodyESR (Erythrocyte Sedimentation Rate)CRP (C-Reactive Protein)
ComparisonRheumatoid Factor IgA Test

Frequently Asked Questions

What is the cost of the Rheumatoid Factor IgA test in India?
The Rheumatoid Factor IgA test cost is Rs 982.8 at DNA Labs India. This price includes free home sample collection in most cities. The final cost may be slightly higher if the sample is collected at the laboratory or if additional tests are added by your doctor.
Is the Rheumatoid Factor IgA test the same as the Rheumatoid Factor test?
No. The standard RF test typically measures IgM rheumatoid factor. The Rheumatoid Factor IgA test specifically measures IgA-class antibodies, which provides additional prognostic information and may be positive even when IgM RF is negative.
Do I need to fast for this test?
No, fasting is not required for the Rheumatoid Factor IgA test. You can eat and drink normally before the blood draw.
What does a positive Rheumatoid Factor IgA result mean?
A positive result means that IgA class autoantibodies are detected in your blood. It strengthens the likelihood of rheumatoid arthritis, especially if you have joint symptoms. However, it may also be positive in other autoimmune diseases, so clinical correlation is essential.
How long does it take to get the results?
If your sample reaches the laboratory by 9 am, the report is usually available the same day. You will receive it through our online portal, email, or WhatsApp.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for the Rheumatoid Factor IgA test in over 150 cities across India. When booking online, the special discounted price includes the home visit.
Can this test diagnose rheumatoid arthritis on its own?
No. The Rheumatoid Factor IgA test is only one part of the diagnostic workup. Doctors also consider physical examination, history, imaging (X-ray, MRI), and other blood tests like anti-CCP, ESR, and CRP before confirming a diagnosis.
Are there any risks associated with the blood test?
The procedure is safe and routine. Minor temporary discomfort, bruising, or soreness at the puncture site can occur. Serious complications are extremely rare.
Who usually orders the Rheumatoid Factor IgA test?
Rheumatologists, immunologists, and internists may order this test when evaluating patients for suspected rheumatoid arthritis or other autoimmune conditions.
What is the reference range for Rheumatoid Factor IgA?
Reference ranges can vary by laboratory and assay method. In our lab, a result below 20 U/mL is considered negative. Values ? 20 U/mL are regarded as positive and require clinical correlation.
Can I take this test if I already have a rheumatoid arthritis diagnosis?
Yes. This test may be used to assess disease severity and prognosis. A positive IgA RF result is associated with a more aggressive disease course, so it can help your doctor adjust treatment plans.
How should I book this test at DNA Labs India?
You can book online through our website or contact our customer support. When booking online, you automatically get the discounted price of Rs 982.8 and free home sample collection. Our phlebotomist will visit your address as per the scheduled slot.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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