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DNA Labs India

ROS 1 (NSCLC) Test

DNA Labs India | ISO 9001:2015 Certified

ROS 1 (NSCLC) Test

Short Name: ROS1 NSCLC

Also known as: ROS1 Gene Mutation Test, ROS1 FISH Test

ROS 1 (NSCLC) Test test available at DNA Labs India for ₹10,500. Uses FISH (Fluorescence In Situ Hybridization) on Tumor tissue samples. Results in 7-8 days. Free home collection in 300+ cities across India.

OncologyAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect ROS1 gene mutations in non-small cell lung cancer for targeted therapy selection and personalized treatment planning.

Test Code
3189
Price
₹10,500
Sample Type
Tumor tissue
Result Time
7-8 days
Fasting Required
No
Method
FISH (Fluorescence In Situ Hybridization)
Step 1

Sample Collection

Consult with a doctor for prescription. Ensure proper documentation and sample labeling.

Method: Biopsy

Step 2

Laboratory Analysis

Tumor tissue sample collected via biopsy procedure under sterile conditions.

Step 3

Report Delivery

Sample is transported to the laboratory at ambient temperature for processing.

Timeline: 7-8 days

Patient Instructions

1
Before the Test:Consult with a doctor for prescription and discuss test implications.
2
During the Test:Biopsy procedure to collect tumor tissue sample.
3
After the Test:Sample analyzed in lab; results available in 7-8 days.

About This Test

Who Should Get This Test

To detect ROS1 gene mutations in non-small cell lung cancer for targeted therapy selection and personalized treatment planning.

How to Prepare

  • Obtain doctor's prescription
  • Ensure sample is properly labeled
  • Transport at ambient temperature
  • Avoid contamination

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early detection of ROS1 mutations can guide targeted therapy for better outcomes in NSCLC patients."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Sample VolumeAs required
ContainerSterile container
Collection MethodBiopsy

Sample Stability

Stable for 24 hours at room temperature
Long-term storage at -20°C if needed
Sample Rejection Criteria:
  • Inadequate sample volume
  • Contaminated sample
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of ROS1 gene rearrangements, guiding treatment decisions for NSCLC.
📊

Positive

ROS1 gene rearrangement detected, consider targeted therapy with ROS1 inhibitors.

Action: Consult oncologist for treatment options.

📊

Negative

No ROS1 gene rearrangement detected.

Action: Discuss alternative diagnostic or treatment plans with healthcare provider.

⚠️ When to Consult a Doctor:

If symptoms persist, worsen, or if test results are positive, consult an oncologist immediately.

Limitations

  • ⚠Test may not detect all ROS1 mutations
  • ⚠Results require clinical correlation
  • ⚠False negatives possible in low-quality samples

Risks & Considerations

  • ●Bleeding at biopsy site
  • ●Infection
  • ●Discomfort during procedure

Interfering Factors

  • ●Poor sample quality
  • ●Insufficient tissue
  • ●Contamination during collection

Compare With Similar Tests

TestROS 1 (NSCLC)EGFR Mutation TestALK Rearrangement TestPD-L1 Expression Test
ComparisonROS 1 (NSCLC)

Frequently Asked Questions

What is ROS1 (NSCLC) testing?
ROS1 (NSCLC) testing is a genetic test that detects mutations in the ROS1 gene in non-small cell lung cancer patients, helping guide targeted therapy.
Who should get tested for ROS1 mutations?
Patients diagnosed with non-small cell lung cancer, especially those with symptoms like persistent cough, chest pain, or unexplained weight loss, should consider testing.
What are the symptoms of ROS1-positive NSCLC?
Symptoms include coughing (sometimes with blood), chest pain, shortness of breath, wheezing, fatigue, and weight loss.
How is the ROS1 test performed?
The test uses Fluorescence In Situ Hybridization (FISH) on a tumor tissue sample collected via biopsy to detect ROS1 gene rearrangements.
What is the cost of ROS1 testing in India?
The cost is approximately INR 10,500 at DNA Labs India, with free home sample collection available.
Is home sample collection available for ROS1 testing?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
How long does it take to get ROS1 test results?
Results are typically available within 7-8 days after sample collection.
What does a positive ROS1 test result mean?
A positive result indicates ROS1 gene rearrangement, suggesting eligibility for targeted therapy with ROS1 inhibitors.
What does a negative ROS1 test result mean?
A negative result means no ROS1 gene rearrangement was detected; discuss alternative options with your doctor.
Is ROS1 testing covered by insurance?
Some insurance plans may cover genetic testing for cancer, but coverage varies. Check with your provider for details.
What are the risks of ROS1 testing?
Risks are minimal and related to the biopsy procedure, such as bleeding or infection at the collection site.
How can I book a ROS1 test with DNA Labs India?
You can book online through the DNA Labs India website or contact them via phone or WhatsApp for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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