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Rubella (German Measles) Avidity IgG Test

DNA Labs India | ISO 9001:2015 Certified

Rubella (German Measles) Avidity IgG Test

Short Name: Rubella Avidity IgG

Also known as: Rubella IgG Avidity, German Measles Avidity Test, Rubella Antibody Avidity Test

Rubella (German Measles) Avidity IgG Test test available at DNA Labs India for ₹679. Uses Enzyme Immunoassay (EIA) on Serum samples. Results in Samples accepted on Monday, Wednesday, and Friday by 9 AM; reports are delivered the same day via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

Serology / Avidity IgG🏠 Home Collection

🩺 Medically Reviewed By

Overview

To confirm the presence of rubella IgG antibodies and measure their avidity index to differentiate recent primary rubella infection from past infection or reinfection. This is especially useful for assessing the risk of congenital rubella syndrome in pregnant women.

Test Code
3615
CPT Code
N/A
ICD Code
N/A
Price
₹679
Sample Type
Serum
Result Time
Samples accepted on Monday, Wednesday, and Friday by 9 AM; reports are delivered the same day via online portal, email, or WhatsApp.
Fasting Required
No
Method
Enzyme Immunoassay (EIA)
Step 1

Sample Collection

No special preparation is required. No fasting is needed. Inform your doctor about any recent vaccinations, as rubella vaccination can affect antibody results.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is drawn from a vein in the arm by a trained phlebotomist. The procedure usually takes only a few minutes.

Step 3

Report Delivery

You may resume normal activities immediately after sample collection. There may be mild bruising at the puncture site, which should resolve on its own.

Timeline: Samples accepted on Monday, Wednesday, and Friday by 9 AM; reports are delivered the same day via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:No special preparation is required. Inform your doctor about any medications, recent vaccinations, or blood transfusions.
2
During the Test:A healthcare professional will clean the site and draw a small amount of blood from your arm. The procedure takes a few minutes.
3
After the Test:You can leave immediately and continue regular activities. Keep the puncture site clean and dry.

About This Test

Who Should Get This Test

To confirm the presence of rubella IgG antibodies and measure their avidity index to differentiate recent primary rubella infection from past infection or reinfection. This is especially useful for assessing the risk of congenital rubella syndrome in pregnant women.

How to Prepare

  • Specimen type: Serum
  • Volume: 2 mL (1 mL minimum)
  • Container: Serum separator tube (SST)
  • Transport: Refrigerated or frozen

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"In pregnancy, rubella IgM results alone can be difficult to interpret. The avidity test helps us determine whether the infection occurred recently, which is essential for counselling the patient about the risk to the fetus."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSerum separator tube (SST)
Collection MethodVenipuncture

Sample Stability

Room temperature
Refrigerated (2-8°C)
Frozen (-20°C)
Sample Rejection Criteria:
  • Severe hemolysis
  • Visible microbial contamination
  • Insufficient sample volume (<1 mL)
  • Unlabelled or mislabelled specimens
  • Sample received outside recommended transport conditions

Understanding Your Results

The avidity index helps distinguish recent primary rubella infection from past infection. Low-avidity IgG antibodies are produced early after infection and become more avid over time.
📊

Suggests current or recent primary rubella infection. If pregnant, urgent obstetric counselling is needed to assess the risk of congenital rubella syndrome.

📊

Suggests past rubella infection or reinfection. This is less likely to be associated with recent primary infection, and the risk to the fetus is lower.

⚠️ When to Consult a Doctor:

If you are pregnant and your avidity test suggests a recent rubella infection, or if you develop symptoms such as fever and rash after exposure, contact your doctor immediately.

Limitations

  • Avidity testing should not be used as a standalone diagnostic test
  • Results should be interpreted in conjunction with rubella IgG and IgM antibody levels
  • Cut-off values may differ between laboratories and assay manufacturers
  • A single avidity index cannot precisely date the infection

Risks & Considerations

  • Mild pain or discomfort during needle insertion
  • Slight bruising at the puncture site
  • Dizziness or fainting (rare)

Interfering Factors

  • Severely haemolysed or lipaemic serum samples may affect immunoassay results
  • Samples with microbial contamination may produce invalid results
  • Recent rubella vaccination may cause positive rubella antibodies and complicate interpretation

Compare With Similar Tests

TestRubella (German Measles) Avidity IgG TestRubella Avidity IgGRubella IgM
ComparisonRubella (German Measles) Avidity IgG Test

Frequently Asked Questions

What is the Rubella (German Measles) Avidity IgG test?
It is a blood test that measures the strength (avidity) of rubella-specific IgG antibodies to distinguish a recent primary infection from a past infection or reinfection.
How much does the Rubella Avidity IgG test cost?
At DNA Labs India, the test costs INR 678.6. Free home sample collection is available for online bookings in many cities.
Why is rubella avidity testing important in pregnancy?
In pregnancy, a recent primary rubella infection can cause congenital rubella syndrome. The avidity test helps determine whether the infection occurred recently, which helps assess the risk to the fetus.
Do I need to fast for this test?
No, fasting is not required. No special preparation is needed before the sample collection.
What sample is required?
A blood sample is required. We collect 2 mL of serum (1 mL minimum) in a serum separator tube.
How long does it take to get reports?
If the sample reaches the lab by 9 AM on Monday, Wednesday, or Friday, reports are available on the same day.
What does a low avidity index mean?
A low avidity index (less than 30%) suggests a current or recent primary rubella infection.
Can this test distinguish between primary infection and reinfection?
Yes, low-avidity IgG is associated with primary infection, while high-avidity IgG is usually seen in past infection or reinfection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings of this test across multiple cities in India.
Who should undergo this test?
It is recommended for pregnant women at risk of rubella infection, women planning pregnancy, and individuals with suspected recent rubella infection.
Are there any risks in the blood test?
Risks are minimal and include slight pain, bruising, or rarely dizziness during blood collection.
Is the test covered by insurance?
Insurance coverage depends on your policy and medical necessity. It is usually covered if ordered by a doctor as medically necessary. Please check with your insurer.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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