Succinylacetone Blood Test
Short Name: Succinylacetone
Also known as: Succinylacetone, SA Blood Test, Succinylacetone DBS, Tyrosinemia Screening
Succinylacetone Blood Test test available at DNA Labs India for ₹5,000. Uses LC-MS/MS on Dried Blood Spot (DBS) on filter paper samples. Results in Reports are typically delivered within 48 hours after the sample is received. For samples scheduled by 9 am on Monday or Thursday, reports are available by Thursday or Monday respectively.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the succinylacetone blood test is to detect elevated levels of succinylacetone in the blood, which strongly indicates Tyrosinemia Type 1. Early identification helps initiate timely treatment, preventing long-term complications and improving patient outcomes.
- Test Code
- 3676
- CPT Code
- 82800
- ICD Code
- E70.21
- Price
- ₹5,000
- Sample Type
- Dried Blood Spot (DBS) on filter paper
- Result Time
- Reports are typically delivered within 48 hours after the sample is received. For samples scheduled by 9 am on Monday or Thursday, reports are available by Thursday or Monday respectively.
- Fasting Required
- No
- Method
- LC-MS/MS
Sample Collection
No fasting required. Provide a brief clinical history including symptoms and suspected condition. Inform lab of any ongoing medications or supplements.
Method: Finger prick / Heel prick
Laboratory Analysis
A small drop of blood will be collected via finger or heel prick and placed on the special filter paper. The procedure is quick and virtually painless.
Report Delivery
The sample should be shipped refrigerated to the laboratory. Do not freeze the filter paper. Results will be delivered within 48 hours.
Timeline: Reports are typically delivered within 48 hours after the sample is received. For samples scheduled by 9 am on Monday or Thursday, reports are available by Thursday or Monday respectively.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the succinylacetone blood test is to detect elevated levels of succinylacetone in the blood, which strongly indicates Tyrosinemia Type 1. Early identification helps initiate timely treatment, preventing long-term complications and improving patient outcomes.
How to Prepare
- Use the provided special filter paper (LPL)
- Collect one drop of fresh blood from finger or heel prick
- Ship the sample refrigerated immediately; DO NOT FREEZE
- Attach the clinical history form with the sample
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early detection of succinylacetone through DBS testing allows timely intervention in tyrosinemia type 1."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample beyond 24 hours at room temperature
- Frozen filter paper
- Clotted or insufficient blood spot
- Unlabelled or mismatched sample
Understanding Your Results
No biochemical evidence of Tyrosinemia Type 1. However, if clinical suspicion persists, consider further metabolic testing.
Confirms the presence of succinylacetone. Immediate referral to a metabolic specialist is required for confirmatory tests (e.g., urine organic acids, genotyping) and management.
May require repeat testing or additional biochemical markers (e.g., tyrosine, alpha-fetoprotein). Interpret in context of clinical history.
Consult a pediatrician or clinical geneticist immediately if the test is positive or if you observe symptoms like jaundice, poor feeding, developmental delays, or unusual body odor. Early intervention is vital.
Limitations
- ⚠Normal levels may be seen in affected individuals already undergoing treatment
- ⚠Confirmation requires additional biochemical and genetic testing
- ⚠False positives possible in certain physiological conditions
Risks & Considerations
- ●Minor pain or bruising at the prick site
- ●Transient bleeding
- ●Risk of infection (extremely low)
Interfering Factors
- ●Improper sample storage or delay in shipping
- ●Exposure to extreme temperatures
- ●Clotted or insufficient blood sample
- ●Contamination of filter paper
Compare With Similar Tests
| Test | Succinylacetone Blood Test | |
|---|---|---|
| Comparison | Succinylacetone Blood Test |
Frequently Asked Questions
What is the succinylacetone blood test?
What is the cost of the succinylacetone blood test at DNA Labs India?
How is the sample collected?
Do I need to fast before the test?
When will I get the results?
Will a positive result confirm Tyrosinemia Type 1?
What are the common symptoms of metabolic disorders?
Can the test be done on newborns?
Is home sample collection available?
What is the reference range for succinylacetone?
How should the sample be stored and transported?
Which doctor should I consult if the test is positive?
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