Syphilis Serology Test
Also known as: RPR Test, VDRL Test, TPHA Test, CLIA Test, Treponemal Assay
Syphilis Serology Test test available at DNA Labs India for ₹1,755. Uses Chemiluminescent Microparticle Immunoassay on Serum samples. Results in Report available next day if sample received by 6 PM.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose syphilis infection by detecting antibodies to Treponema pallidum in the blood, and to monitor treatment effectiveness.
- Test Code
- 1426
- Price
- ₹1,755
- Sample Type
- Serum
- Result Time
- Report available next day if sample received by 6 PM.
- Fasting Required
- No
- Method
- Chemiluminescent Microparticle Immunoassay
Sample Collection
No special preparation required. Inform your doctor about any medications or health conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: Report available next day if sample received by 6 PM.
Patient Instructions
About This Test
Who Should Get This Test
To diagnose syphilis infection by detecting antibodies to Treponema pallidum in the blood, and to monitor treatment effectiveness.
How to Prepare
- Ensure the sample is collected in a 2 mL SST tube
- Ship the sample refrigerated or frozen
- Label the sample correctly with patient details
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early detection of syphilis through serology testing is crucial for effective treatment and preventing severe complications like organ damage."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or contaminated sample
- Improper storage or transport conditions
Understanding Your Results
Non-reactive
No antibodies detected, suggesting no current or past syphilis infection. However, early infections may yield false negatives.
Reactive
Antibodies detected, indicating current or past syphilis infection. A nontreponemal test (e.g., RPR/VDRL) is needed to assess disease activity and treatment history.
If the test is reactive, or if symptoms persist after treatment, consult an infectious disease specialist for further evaluation and management.
Limitations
- ⚠Treponemal tests may remain reactive for life post-treatment, requiring nontreponemal tests (e.g., RPR/VDRL) for disease state assessment
- ⚠Cannot distinguish between current and past infections without additional testing
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or fainting
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Recent antibiotic therapy
- ●Cross-reactivity with other infections
Frequently Asked Questions
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