Typhus Fever (Rickettsia) Antibodies IgG & IgM Test
Short Name: Typhus Fever IgG/IgM
Also known as: Typhus Fever Serology, Rickettsia IgG & IgM Antibodies, Murine Typhus Antibody Test
Typhus Fever (Rickettsia) Antibodies IgG & IgM Test test available at DNA Labs India for ₹13,000. Uses Immunofluorescence Assay (IFA) on Serum samples. Results in Reports are available in 2–3 weeks after the sample reaches the reference laboratory. Samples must be submitted by the 7th of the month to meet the reporting schedule.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The primary purpose of this test is to detect and quantify IgG and IgM antibodies against the typhus group of Rickettsia species. It aids in the laboratory diagnosis of recent or past typhus infection, helps differentiate typhus from other febrile illnesses, and supports epidemiological investigations.
- Test Code
- 3713
- Price
- ₹13,000
- Sample Type
- Serum
- Result Time
- Reports are available in 2–3 weeks after the sample reaches the reference laboratory. Samples must be submitted by the 7th of the month to meet the reporting schedule.
- Fasting Required
- No
- Method
- Immunofluorescence Assay (IFA)
Sample Collection
No fasting is required. Please ensure the Test Send Out Consent Form (Form 35) is completely filled and signed before sample collection.
Method: Venipuncture (blood draw)
Laboratory Analysis
A blood sample is drawn from a vein in your arm; the procedure takes less than five minutes.
Report Delivery
You may resume normal activities immediately. No special precautions are needed after blood draw.
Timeline: Reports are available in 2–3 weeks after the sample reaches the reference laboratory. Samples must be submitted by the 7th of the month to meet the reporting schedule.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of this test is to detect and quantify IgG and IgM antibodies against the typhus group of Rickettsia species. It aids in the laboratory diagnosis of recent or past typhus infection, helps differentiate typhus from other febrile illnesses, and supports epidemiological investigations.
How to Prepare
- Ensure the Test Send Out Consent Form (Form 35) is duly filled and signed.
- No fasting or special diet is required.
- Sample must be collected in a serum separator tube (SST).
- The sample should be transported refrigerated or frozen after collection.
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"IgM and IgG antibody patterns help determine whether the infection is recent or past, guiding clinicians in timely antimicrobial therapy. This test is an important tool in the diagnosis of typhus group rickettsial infections."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed, lipemic, or contaminated sample
- Improper labeling of sample
- Missing or incomplete Test Send Out Consent Form (Form 35)
Understanding Your Results
Indicates acute or recent infection, usually within the first few weeks of symptom onset.
Suggests past infection or a later phase of the illness. A rising titre in paired samples may confirm active infection.
Indicates a current or recent infection with the typhus group rickettsiae.
Does not support a diagnosis of typhus fever, especially if the sample was collected very early. Consider repeat testing after 7–14 days if clinical suspicion remains high.
If you experience high fever, severe headache, muscle aches, or a rash, especially after exposure to fleas, lice, or ticks, or after travelling to typhus-endemic areas, consult a doctor promptly.
Limitations
- ⚠IgM antibodies may not be detectable during the first week of infection
- ⚠Test may not distinguish between Rickettsia typhi and Rickettsia prowazekii due to cross-reactivity
- ⚠Immunocompromised patients may have delayed or absent antibody responses
Risks & Considerations
- ●Mild bruising at the puncture site
- ●Small chance of infection
- ●Dizziness or fainting during blood draw
Interfering Factors
- ●Rheumatoid factor may cause false-positive IgM results
- ●Cross-reactivity with other rickettsial species
- ●Recent vaccination or past infection may affect IgG levels
Frequently Asked Questions
What is the Typhus Fever (Rickettsia) Antibodies IgG & IgM test?
Why is this test performed?
Is fasting required before the test?
How is the blood sample collected?
How long does it take to get results?
What does a positive IgM antibody result mean?
What does a positive IgG antibody result mean?
Can this test distinguish between endemic and epidemic typhus?
What is the cost of the Typhus Fever (Rickettsia) Antibodies IgG & IgM test in India?
Is home sample collection available for this test?
How should the blood sample be stored before shipping?
Are there any risks associated with the blood test?
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