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DNA Labs India

Vasculitis Panel Test

DNA Labs India | ISO 9001:2015 Certified

Vasculitis Panel Test

Short Name: Vasculitis Panel

Also known as: Vasculitis Autoantibody Panel, ANCA Panel

Vasculitis Panel Test test available at DNA Labs India for ₹8,000. Uses EIA, IFA on Serum samples. Results in Report is available the next day after sample submission. Samples are accepted on Tuesday, Thursday, and Saturday by 9 am.. Free home collection in 300+ cities across India.

Autoantibody Panel🏠 Home Collection

🩺 Medically Reviewed By

Overview

The Vasculitis Panel Test is performed to detect antibodies associated with autoimmune vasculitis. It includes ANA by IFA, ANCA-MPO by EIA, ANCA-PR3 by EIA, and Anti-dsDNA by EIA. These tests help in the diagnosis and management of primary systemic vasculitis and vasculitis secondary to connective tissue disorders.

Test Code
3724
Price
₹8,000
Sample Type
Serum
Result Time
Report is available the next day after sample submission. Samples are accepted on Tuesday, Thursday, and Saturday by 9 am.
Fasting Required
Yes (8 hours)
Method
EIA, IFA
Step 1

Sample Collection

Overnight fasting is preferred. Please inform your doctor about any medications you are taking, especially immunosuppressants, steroids, or drugs that may affect antibody levels. Wear clothing with loose sleeves for easy access to the arm.

Method: Venipuncture

Step 2

Laboratory Analysis

A trained phlebotomist will collect a blood sample from a vein in your arm. The procedure takes a few minutes and may cause mild discomfort.

Step 3

Report Delivery

No special precautions are required. You may resume your normal diet and activities immediately after sample collection. Keep the puncture site clean and dry.

Timeline: Report is available the next day after sample submission. Samples are accepted on Tuesday, Thursday, and Saturday by 9 am.

Patient Instructions

1
Before the Test:Overnight fasting is preferred. Inform your doctor about all current medications and supplements. A detailed medical history and clinical examination are essential before interpreting these results.
2
During the Test:A blood sample is drawn from a vein in your arm. The test itself has no significant risks; you may feel a brief pricking sensation.
3
After the Test:You can leave immediately after sample collection. No dietary or activity restrictions are needed after the test. Your doctor will discuss the results with you.

About This Test

Who Should Get This Test

The Vasculitis Panel Test is performed to detect antibodies associated with autoimmune vasculitis. It includes ANA by IFA, ANCA-MPO by EIA, ANCA-PR3 by EIA, and Anti-dsDNA by EIA. These tests help in the diagnosis and management of primary systemic vasculitis and vasculitis secondary to connective tissue disorders.

How to Prepare

  • Overnight fasting is preferred before the test.
  • Sample must be collected in an SST (Serum Separator Tube).
  • The sample should be shipped refrigerated or frozen for transport.
  • Specimen should reach the laboratory within 6 hours at room temperature, 72 hours refrigerated, or 2 weeks frozen.
  • Please provide complete clinical history and medication details when booking the test.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This panel is an important screen for suspected systemic vasculitis, but results must always be interpreted in the context of clinical findings and, when necessary, tissue biopsy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume3 mL (2 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature (25°C)6 hours
Refrigerated (2-8°C)72 hours
Frozen (-20°C)2 weeks
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Improperly labelled samples
  • Samples received in EDTA or heparin instead of SST
  • Samples stored beyond stability limits
  • Grossly icteric or contaminated samples

Understanding Your Results

Results of the Vasculitis Panel Test should be interpreted by a qualified specialist in the context of the patient's clinical presentation. A single positive autoantibody is not diagnostic by itself; correlation with clinical findings and additional investigations is essential.
📊

ANA positive

Suggests possible autoimmune process; further evaluation with specific autoantibodies is needed.

📊

ANCA-MPO positive

May indicate microscopic polyangiitis or eosinophilic granulomatosis with polyangiitis.

📊

ANCA-PR3 positive

May indicate granulomatosis with polyangiitis (Wegener's granulomatosis).

📊

Anti-dsDNA positive

Strongly associated with systemic lupus erythematosus.

📊

All parameters negative

Reduces the likelihood of ANCA-associated vasculitis, but does not completely exclude vasculitis.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms such as unexplained fever, weight loss, fatigue, muscle or joint pain, skin rashes, numbness or tingling, shortness of breath, chest pain, abdominal pain, or blood in urine. Early evaluation is critical for suspected vasculitis.

Limitations

  • This panel does not detect all forms of vasculitis.
  • Negative results do not exclude vasculitis, especially in limited or single-organ disease.
  • Positive results may occur in other autoimmune, infectious, drug-induced, or neoplastic conditions.
  • Histopathological confirmation via biopsy may be required for definitive diagnosis.
  • Reference ranges may vary between laboratories; results should be interpreted by a qualified clinician.

Risks & Considerations

  • Mild pain or bruising at the venipuncture site
  • Rare local infection (prevented by sterile technique)
  • Excessive bleeding or hematoma formation (uncommon)

Interfering Factors

  • Immunosuppressive therapy (e.g., corticosteroids, rituximab) may cause false-negative ANCA results.
  • Acute infections or inflammatory conditions may lead to false-positive ANA or ANCA results.
  • Hemolysis, lipemia, or prolonged sample storage may affect assay accuracy.
  • Drugs such as hydralazine, procainamide, and minocycline can induce ANCA positivity.
  • Recent blood transfusion or vaccination may cause transient autoantibody positivity.

Frequently Asked Questions

What is the Vasculitis Panel Test?
The Vasculitis Panel Test is a blood test that detects antibodies associated with vasculitis and related autoimmune disorders. The panel includes ANA, ANCA-MPO, ANCA-PR3, and anti-dsDNA.
Why is the Vasculitis Panel Test done?
It is done to help diagnose vasculitis, especially ANCA-associated vasculitis such as granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis. It is also useful in evaluating other autoimmune conditions like systemic lupus erythematosus.
How much does the Vasculitis Panel Test cost in India?
The Vasculitis Panel Test costs Rs 8000 at DNA Labs India. Prices may vary at other laboratories.
Is fasting required for the Vasculitis Panel Test?
Overnight fasting is preferred but not strictly mandatory. You should follow the specific instructions provided by the laboratory.
What sample is needed for this test?
A serum sample of 3 mL (minimum 2 mL) collected in an SST (Serum Separator Tube) is required.
How long will the report take?
Samples are accepted on Tuesday, Thursday, and Saturday by 9 am, and the report is available the next day.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings for the Vasculitis Panel Test across multiple cities in India.
Which antibodies are tested in this panel?
The panel tests ANA (antinuclear antibody) by IFA, ANCA-MPO and ANCA-PR3 by EIA, and anti-dsDNA antibody by EIA.
Can the Vasculitis Panel Test diagnose vasculitis alone?
No. The test provides supportive evidence, but the diagnosis of vasculitis often requires clinical evaluation, imaging, and sometimes tissue biopsy.
What does a positive ANCA-PR3 indicate?
ANCA-PR3 is strongly associated with granulomatosis with polyangiitis (Wegener's granulomatosis). However, a positive result must be interpreted in the clinical context.
What does a positive anti-dsDNA indicate?
Anti-dsDNA is highly specific for systemic lupus erythematosus. It may also be seen in drug-induced lupus or other autoimmune conditions, and clinical correlation is essential.
Which doctor should I consult if the test is abnormal?
You should consult a rheumatologist or an allergist/immunologist for further evaluation and management of suspected vasculitis or autoimmune disease.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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