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DNA Labs India

ZNF783 Gene Prostate cancer NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

ZNF783 Gene Prostate cancer NGS Genetic Test

Short Name: ZNF783 Prostate NGS

Also known as: ZNF783 Gene Mutation Test, Prostate Cancer NGS Panel, ZNF783 Genetic Screening

ZNF783 Gene Prostate cancer NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.

GeneticMaleAdult🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The primary purpose of the ZNF783 Gene Prostate Cancer NGS Genetic Test is to detect mutations in the ZNF783 gene that may increase the risk of developing prostate cancer. This test is intended for individuals with a family history of prostate cancer, those with suspicious symptoms, or those seeking proactive risk assessment. By identifying genetic variants, the test enables early intervention, personalized surveillance strategies, and informed reproductive decisions. It also assists oncologists in tailoring treatment options based on the genetic profile of the tumor.

Test Code
6018
CPT Code
81479
ICD Code
C61
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results are typically available within 3 to 4 weeks after the sample reaches the laboratory.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation required. However, a genetic counseling session is recommended prior to testing to discuss implications. Please bring any relevant medical records and family history information.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm, or a few drops of blood will be collected on an FTA card. The procedure is quick and minimally invasive.

Step 3

Report Delivery

You can resume normal activities immediately. The sample will be sent to our laboratory for analysis. Results will be available in 3-4 weeks.

Timeline: Results are typically available within 3 to 4 weeks after the sample reaches the laboratory.

Patient Instructions

1
Before the Test:No special preparation is required. However, a genetic counseling session is recommended to discuss the purpose, risks, and benefits of testing.
2
During the Test:A blood sample is drawn by a trained phlebotomist. The procedure takes about 5 minutes.
3
After the Test:You can resume normal activities. Results will be shared with you and your physician, and a genetic counselor will explain the implications.

About This Test

Who Should Get This Test

The primary purpose of the ZNF783 Gene Prostate Cancer NGS Genetic Test is to detect mutations in the ZNF783 gene that may increase the risk of developing prostate cancer. This test is intended for individuals with a family history of prostate cancer, those with suspicious symptoms, or those seeking proactive risk assessment. By identifying genetic variants, the test enables early intervention, personalized surveillance strategies, and informed reproductive decisions. It also assists oncologists in tailoring treatment options based on the genetic profile of the tumor.

How to Prepare

  • Ensure the FTA card is properly labeled with patient details
  • For blood collection, use EDTA vacutainer and mix gently
  • Avoid hemolysis by gentle handling
  • Store sample at room temperature if shipping within 24 hours, otherwise refrigerate

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Genetic testing for ZNF783 mutations can identify individuals at elevated risk for prostate cancer, enabling earlier surveillance and personalized management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume2-3 ml blood or 1 FTA spot
ContainerEDTA vacutainer or FTA card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Blood: 7 days at 2-8°C
FTA card: 6 months at room temperature
Extracted DNA: 1 year at -20°C
Sample Rejection Criteria:
  • Hemolyzed blood sample
  • Insufficient sample volume
  • Improperly labeled sample
  • Sample received after prolonged transit without proper storage

Understanding Your Results

The interpretation of the ZNF783 gene test results should be performed by a qualified geneticist or oncologist. Results are reported as positive, negative, or variant of uncertain significance (VUS).
📊

Positive (Pathogenic mutation)

Increased risk of prostate cancer. Recommend enhanced surveillance and consider preventive strategies.

📊

Negative (No mutation)

No increased risk from ZNF783 gene. Continue standard screening guidelines.

📊

Variant of Uncertain Significance (VUS)

Insufficient evidence to determine risk. Further family studies or functional assays may be needed.

⚠️ When to Consult a Doctor:

Consult your doctor if you have symptoms such as frequent urination, difficulty urinating, blood in urine or semen, painful ejaculation, or persistent pain in the lower back, hips, or thighs. Also, if you have a family history of prostate cancer, discuss genetic testing with your healthcare provider.

Limitations

  • ⚠Test only analyzes the ZNF783 gene, not other prostate cancer-related genes
  • ⚠Negative result does not rule out prostate cancer risk from other genetic or environmental factors
  • ⚠Variant of uncertain significance (VUS) may require further family studies
  • ⚠Not a diagnostic test for prostate cancer; clinical correlation is essential

Risks & Considerations

  • ●Minimal risk of bruising or infection at the blood draw site
  • ●Psychological impact of learning genetic risk
  • ●Potential for uncertain results (VUS)

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Recent blood transfusion (within 2 weeks)
  • ●Bone marrow transplantation
  • ●Clonal hematopoiesis of indeterminate potential (CHIP)

Compare With Similar Tests

TestZNF783 Gene Prostate cancer NGS Genetic TestBRCA1/BRCA2 Gene TestHOXB13 Gene TestProstate Cancer Comprehensive Panel
ComparisonZNF783 Gene Prostate cancer NGS Genetic Test

Frequently Asked Questions

What is the ZNF783 gene?
ZNF783 is a zinc finger protein gene involved in transcriptional regulation and cell growth. Mutations in this gene have been associated with increased risk of prostate cancer.
Who should consider this test?
Men with a family history of prostate cancer, early-onset prostate cancer, or those with suspicious symptoms may benefit from this genetic test.
How is the test performed?
The test requires a blood sample or a few drops of blood on an FTA card. The sample is sent to our laboratory for NGS analysis.
What is the cost of the test?
The cost is INR 20,000, which includes genetic counseling and the NGS analysis. Free home sample collection is available in many cities.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after the sample is received.
Is fasting required before the test?
No, fasting is not required for this genetic test.
Can this test diagnose prostate cancer?
No, this test identifies genetic mutations that increase risk. It is not a diagnostic test for prostate cancer. Clinical evaluation and other tests like PSA and biopsy are needed for diagnosis.
What does a positive result mean?
A positive result indicates the presence of a pathogenic mutation in the ZNF783 gene, which may increase your risk of developing prostate cancer. It is recommended to discuss with your doctor for enhanced surveillance.
What if the result is a variant of uncertain significance (VUS)?
A VUS means the variant's impact is unknown. Further family studies or additional testing may be recommended to clarify the risk.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings in over 200 cities across India.
Will my insurance cover this test?
Insurance coverage varies. It is advisable to check with your insurance provider. We also offer cashless options for some schemes.
How accurate is the NGS test?
NGS is highly accurate with >99% sensitivity for detecting mutations in the targeted gene. Our laboratory is NABL accredited.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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