Factor VIII Functional / Activity Test
Short Name: Factor VIII Activity Test
Also known as: Factor VIII Assay, Hemophilia A Test
Factor VIII Functional / Activity Test test available at DNA Labs India for ₹3,200. Uses Electromechanical Clot Detection on Whole blood samples. Results in Reports are typically available the same day if the sample is received by 11 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Gottipati Vemkateswarlu
Consultant Hematologist · Reg: AMC4946
Last reviewed: September 7, 2026
Overview
The primary purpose of the Factor VIII Activity Test is to diagnose Hemophilia A by measuring the activity level of Factor VIII in the blood. It helps in confirming the deficiency, assessing its severity, and monitoring treatment effectiveness. This test is also used to evaluate unexplained bleeding episodes and guide clinical management.
- Test Code
- 544
- Price
- ₹3,200
- Sample Type
- Whole blood
- Result Time
- Reports are typically available the same day if the sample is received by 11 am.
- Fasting Required
- Yes
- Method
- Electromechanical Clot Detection
Sample Collection
Overnight fasting is preferred. Patient should discontinue Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling, with prior consent from the treating physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect 3 mL of whole blood from a vein in the arm using a blue top (Sodium Citrate) tube.
Report Delivery
The sample must be mixed thoroughly by inversion and transported to the lab within 4 hours. If delayed, prepare platelet-poor plasma (PPP) by centrifugation and freeze immediately.
Timeline: Reports are typically available the same day if the sample is received by 11 am.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Factor VIII Activity Test is to diagnose Hemophilia A by measuring the activity level of Factor VIII in the blood. It helps in confirming the deficiency, assessing its severity, and monitoring treatment effectiveness. This test is also used to evaluate unexplained bleeding episodes and guide clinical management.
How to Prepare
- Overnight fasting is preferred.
- Discontinue Heparin for 1 day and Oral Anticoagulants for 7 days with physician consent.
- Fill Coagulation Requisition Form (Form 15) mandatorily.
- Collect 3 mL whole blood in Blue Top (Sodium Citrate) tube.
- Mix by inversion and transport within 4 hours.
- If transport delayed, prepare PPP as described and freeze.
Doctor's Notes
Reviewed by Dr Gottipati Vemkateswarlu — MBBS, MD (Haematology) · Reg. No. AMC4946
"Factor VIII testing is essential for diagnosing bleeding disorders. Patients with symptoms like easy bruising or prolonged bleeding should consider this test under medical guidance to prevent complications."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly labeled sample
- Clotted sample
- Insufficient volume
- Sample not collected in correct tube
- Form 15 not filled
Understanding Your Results
Low (below 50%)
Indicates Factor VIII deficiency, consistent with Hemophilia A. Severity depends on the level: mild (5-40%), moderate (1-5%), severe (<1%).
Normal (50-150%)
Rules out significant Factor VIII deficiency. Further tests may be needed if symptoms persist.
High (above 150%)
May be seen in inflammation, pregnancy, or other conditions. Consult a physician for evaluation.
If you experience symptoms of bleeding disorders such as prolonged bleeding, easy bruising, or if your test results are abnormal, consult a haematologist or your healthcare provider immediately.
Limitations
- ⚠May not detect carrier status in females
- ⚠Requires proper sample handling and transport
- ⚠Results can be affected by other coagulation factors
Risks & Considerations
- ●Bruising at the puncture site
- ●Infection (rare)
- ●Dizziness or lightheadedness during blood draw
Interfering Factors
- ●Heparin therapy (discontinue for 1 day before test)
- ●Oral anticoagulants (discontinue for 7 days before test)
- ●Recent blood transfusions
- ●Liver disease
- ●Inflammatory conditions
Compare With Similar Tests
| Test | Factor VIII Functional / Activity Test | Prothrombin Time (PT) | Activated Partial Thromboplastin Time (aPTT) | Factor IX Activity Test |
|---|---|---|---|---|
| Comparison | Factor VIII Functional / Activity Test |
Frequently Asked Questions
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