Factor XII Functional Test
Also known as: Factor XII Assay, Hageman Factor Functional Test
Factor XII Functional Test test available at DNA Labs India for ₹4,500. Uses Photo-optical Clot Detection on Whole Blood samples. Results in Reports available next day if sample received by 9 am on Thursday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Gottipati Vemkateswarlu
Consultant Hematologist · Reg: AMC4946
Last reviewed: September 7, 2026
Overview
To diagnose and monitor blood clotting disorders related to Factor XII deficiency and assess bleeding risk before medical procedures.
- Test Code
- 543
- Price
- ₹4,500
- Sample Type
- Whole Blood
- Result Time
- Reports available next day if sample received by 9 am on Thursday.
- Fasting Required
- Yes (12 hours)
- Method
- Photo-optical Clot Detection
Sample Collection
Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. Discontinue Heparin for 1 day and Oral Anticoagulants for 7 days prior, with physician consent.
Method: Venipuncture
Laboratory Analysis
Blood sample drawn via venipuncture into a blue top sodium citrate tube.
Report Delivery
Sample must be processed within 4 hours or prepared as platelet-poor plasma and frozen.
Timeline: Reports available next day if sample received by 9 am on Thursday.
Patient Instructions
About This Test
Who Should Get This Test
To diagnose and monitor blood clotting disorders related to Factor XII deficiency and assess bleeding risk before medical procedures.
How to Prepare
- Fast overnight
- Fill Coagulation Requisition Form (Form 15)
- Discontinue Heparin for 1 day and Oral Anticoagulants for 7 days with physician consent
- Collect 3 mL whole blood in blue top tube
- Mix by inversion
- Transport to lab within 4 hours or prepare PPP and freeze
Doctor's Notes
Reviewed by Dr Gottipati Vemkateswarlu — MBBS, MD (Haematology) · Reg. No. AMC4946
"This test is crucial for evaluating Factor XII function in patients with suspected clotting disorders. Accurate diagnosis helps in managing bleeding risks effectively."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Incorrect tube
- Clotted sample
- Insufficient volume
- Delayed transport without PPP preparation
Understanding Your Results
May indicate Factor XII deficiency, which can be associated with bleeding disorders or thrombosis.
Action: Consult a haematologist for further evaluation.
Level: Low
Factor XII activity is within normal limits.
Action: No immediate concern, but correlate with clinical symptoms.
Level: Normal
If you experience symptoms like unexplained bleeding, heavy periods, or if advised by your physician based on test results.
Limitations
- ⚠Cannot differentiate between deficiency and inhibitor; may be affected by other coagulation factors.
Risks & Considerations
- ●Slight pain
- ●Bruising
- ●Infection at puncture site
Interfering Factors
- ●Heparin therapy
- ●Oral anticoagulant therapy
- ●Improper sample collection or processing
Compare With Similar Tests
| Test | Factor XII Functional Test | Prothrombin Time (PT) Test | Activated Partial Thromboplastin Time (aPTT) Test |
|---|---|---|---|
| Comparison | Factor XII Functional Test |
Frequently Asked Questions
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