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DNA Labs India

FLT3 Gene Mutation Quantitative Monitor Test

DNA Labs India | ISO 9001:2015 Certified

FLT3 Gene Mutation Quantitative Monitor Test

Short Name: FLT3 Mutation Monitor Test

Also known as: FLT3-ITD Quantitative Test, FLT3 Mutation Quantification, FLT3 Gene Monitoring Assay

FLT3 Gene Mutation Quantitative Monitor Test test available at DNA Labs India for ₹4,500. Uses Real-Time PCR on Whole blood or Bone marrow samples. Results in Reports are available within 2-3 days after sample receipt, with delivery via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

Molecular Diagnostic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to quantify FLT3 gene mutations, specifically FLT3-ITD, in the blood or bone marrow of AML patients. It aids in diagnosing FLT3-positive leukemia, monitoring mutation levels during treatment, assessing response to therapy, and evaluating prognosis. Regular monitoring helps in early detection of relapse or resistance, guiding clinical decisions for better patient outcomes.

Test Code
613
Price
₹4,500
Sample Type
Whole blood or Bone marrow
Result Time
Reports are available within 2-3 days after sample receipt, with delivery via online portal, email, or WhatsApp.
Fasting Required
No
Method
Real-Time PCR
Step 1

Sample Collection

Ensure the MRD Requisition Form (Form 22) is duly filled with historical patient data. No fasting is required, but avoid strenuous activity before sample collection.

Method: Blood draw or Bone marrow aspirate

Step 2

Laboratory Analysis

A blood draw or bone marrow aspirate will be performed by a trained phlebotomist. The sample is collected in an EDTA tube to prevent clotting.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. The sample is stored refrigerated and shipped to the laboratory for analysis.

Timeline: Reports are available within 2-3 days after sample receipt, with delivery via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:Complete the MRD Requisition Form and ensure sample collection is scheduled as per instructions.
2
During the Test:Sample is analyzed using Real-Time PCR to quantify FLT3-ITD mutations. The process is automated in the laboratory.
3
After the Test:Results are generated and reported within the turnaround time. Follow-up with your physician for interpretation.

About This Test

Who Should Get This Test

The purpose of this test is to quantify FLT3 gene mutations, specifically FLT3-ITD, in the blood or bone marrow of AML patients. It aids in diagnosing FLT3-positive leukemia, monitoring mutation levels during treatment, assessing response to therapy, and evaluating prognosis. Regular monitoring helps in early detection of relapse or resistance, guiding clinical decisions for better patient outcomes.

How to Prepare

  • Duly filled MRD Requisition Form (Form 22) with historical data is mandatory.
  • Use 5 mL whole blood or bone marrow in a Lavender Top (EDTA) tube.
  • Ship refrigerated; do not freeze the sample.
  • Label the sample correctly with patient details.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This quantitative test is essential for monitoring FLT3 mutation levels in AML patients, aiding in treatment decisions and prognosis assessment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood or Bone marrow
Sample Volume5 mL (3 mL min.)
ContainerLavender Top (EDTA) tube
Collection MethodBlood draw or Bone marrow aspirate

Sample Stability

Room Temperature
Refrigerator (2-8°C)
Frozen
Sample Rejection Criteria:
  • Sample volume less than 3 mL
  • Wrong container type (not EDTA tube)
  • Sample hemolyzed or clotted
  • Missing or incomplete MRD Requisition Form
  • Improper storage (e.g., frozen)

Understanding Your Results

Results indicate the quantity of FLT3-ITD mutations. A positive result shows mutation presence, while a negative result suggests no detectable mutation. Levels are monitored over time to assess treatment response or disease progression.
A high FLT3-ITD allele ratio may indicate aggressive disease and poor prognosis.
Decreasing mutation levels during treatment suggest therapeutic efficacy.
Rising levels post-treatment may signal relapse or resistance.
Results should be interpreted by a hematologist in conjunction with clinical data.
⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms of AML (e.g., fatigue, fever, easy bruising) or if this test is part of ongoing cancer management. Seek advice for interpreting results or adjusting treatment plans.

Limitations

  • ⚠Detects only FLT3-ITD mutations; other FLT3 variants may require different assays
  • ⚠Results are quantitative but may vary based on sample quality and lab protocols
  • ⚠Not a standalone diagnostic; must be correlated with clinical findings and other tests
  • ⚠Limited sensitivity for very low mutation levels

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare infection risk at the puncture site
  • ●No significant risks from the test itself

Interfering Factors

  • ●Hemolyzed or clotted blood samples
  • ●Sample contamination during collection or transport
  • ●Inadequate sample volume or improper storage
  • ●Previous treatments affecting DNA integrity

Frequently Asked Questions

What is the FLT3 gene mutation quantitative monitor test?
It is a blood or bone marrow test that quantifies FLT3-ITD mutations using Real-Time PCR, primarily for monitoring Acute Myeloid Leukemia (AML) patients.
Why is this test important for AML?
FLT3 mutations are common in AML and affect prognosis. This test helps track mutation levels to guide treatment and detect relapse early.
How much does the FLT3 mutation monitor test cost in India?
The cost is INR 4500.0, which includes home sample collection and report delivery.
What sample is required for this test?
5 mL of whole blood or bone marrow in an EDTA tube is required.
Is fasting needed before the test?
No, fasting is not required. However, the MRD Requisition Form must be filled.
How long does it take to get results?
Results are typically available within 2-3 days after sample collection.
Can this test diagnose AML?
It helps in diagnosing FLT3-positive AML but is used alongside other tests like bone marrow biopsy for confirmation.
Is home sample collection available?
Yes, free home collection is offered across India for online bookings.
What if the test result is positive?
A positive result indicates FLT3 mutation presence. Your doctor will use this to plan treatment, such as targeted therapies.
Are there any risks associated with this test?
Risks are minimal, similar to standard blood draws, like slight pain or bruising.
How often should this test be repeated?
Frequency depends on treatment plans, often during therapy to monitor response and detect changes in mutation levels.
What is the accuracy of the FLT3 mutation monitor test?
The test has high accuracy with optimized sensitivity and specificity for detecting FLT3-ITD mutations, but results should be interpreted in clinical context.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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