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HLA DNA Typing for Bone Marrow Transplant: 10 Antigens PCR Test

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HLA DNA Typing for Bone Marrow Transplant: 10 Antigens PCR Test

Short Name: HLA Typing 10 Ag PCR

Also known as: HLA DNA Typing for BMT, 10 Antigen HLA PCR Test, Bone Marrow Transplant HLA Typing

HLA DNA Typing for Bone Marrow Transplant: 10 Antigens PCR Test test available at DNA Labs India for ₹24,570. Uses SSP-PCR on Whole blood samples. Results in 10-12 days. Free home collection in 300+ cities across India.

PCR-based HLA typingAll ages (as per transplant indication)🏠 Home Collection

🩺 Medically Reviewed By

Overview

Low-resolution typing for HLA-A, B, C, DR, and DQ antigens to assess donor-recipient compatibility in bone marrow transplantation.

Test Code
806
Price
₹24,570
Sample Type
Whole blood
Result Time
10-12 days
Fasting Required
No
Method
SSP-PCR
Step 1

Sample Collection

No special preparation required

Method: Venipuncture

Step 2

Laboratory Analysis

Standard blood draw procedure using venipuncture

Step 3

Report Delivery

Ship refrigerated; do not freeze

Timeline: 10-12 days

Patient Instructions

1
Before the Test:No special preparation required
2
During the Test:PCR amplification and sequencing of HLA genes
3
After the Test:Sample analysis and report generation

About This Test

Who Should Get This Test

Low-resolution typing for HLA-A, B, C, DR, and DQ antigens to assess donor-recipient compatibility in bone marrow transplantation.

How to Prepare

  • Collect 4 mL whole blood in Lavender Top (EDTA) tube or 6 mL in Yellow Top (ACD) tube
  • Ensure proper labeling and mix gently
  • Ship refrigerated immediately; avoid freezing

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"HLA DNA typing is crucial for ensuring donor-recipient compatibility in bone marrow transplants to prevent graft-versus-host disease and improve transplant success rates."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume4 mL (min 3 mL) or 6 mL (min 3 mL)
ContainerLavender Top (EDTA) tube or Yellow Top (ACD) tube
Collection MethodVenipuncture

Sample Stability

Refrigerator: 96 hours
Room temperature: Not stable
Frozen: Not stable
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Frozen samples
  • Insufficient volume (< 3 mL)
  • Improperly labeled tubes

Understanding Your Results

HLA DNA typing results indicate the specific HLA antigens present. Compatibility is determined by comparing donor and recipient antigens; a match reduces rejection risk.
100% match for all 10 antigens is ideal for bone marrow transplant
Partial matches may increase risk of graft-versus-host disease
Results are used to assess transplant feasibility and plan immunosuppressive therapy
⚠️ When to Consult a Doctor:

Consult a hematologist before transplant planning if symptoms like fever, fatigue, or skin rash occur post-transplant, or for genetic counseling.

Limitations

  • Low-resolution typing; may require high-resolution typing for precise matching
  • Cannot detect all HLA alleles
  • Results are specific to current testing methods

Risks & Considerations

  • Minor bruising or infection at blood draw site
  • Minimal risk of hemolysis during collection

Interfering Factors

  • Hemolyzed or lipemic samples
  • Improper sample storage (freezing)
  • Insufficient sample volume

Compare With Similar Tests

TestHLA DNA Typing for Bone Marrow Transplant: 10 Antigens PCR Test
ComparisonHLA DNA Typing for Bone Marrow Transplant: 10 Antigens PCR Test

Frequently Asked Questions

What is HLA DNA typing?
HLA DNA typing is a test that analyzes Human Leukocyte Antigen genes to determine an individual's unique genetic makeup, crucial for immune compatibility in transplants.
Why is HLA typing important for bone marrow transplant?
It ensures donor-recipient compatibility to prevent graft-versus-host disease and improve transplant success rates.
How is the test performed?
The test uses PCR technology to amplify and sequence specific HLA gene regions from a blood sample.
What sample is required for the test?
4 mL or 6 mL of whole blood in EDTA or ACD tubes, shipped refrigerated.
Is fasting required for HLA typing?
No, no fasting or special preparation is required.
How long does it take to get results?
Results are typically available in 10-12 days.
What does a 100% HLA match mean?
It indicates full compatibility for all 10 antigens (HLA-A, B, C, DR, DQ), which is ideal for transplant.
What are the risks of HLA mismatch?
HLA mismatch increases the risk of graft-versus-host disease and transplant rejection.
Can this test be used for cord blood registry?
Yes, it is used for HLA typing in cord blood registry and stem cell transplantation.
What is the cost of HLA DNA typing in India?
The cost is INR 24570 at DNA Labs India, with free home collection available.
How do I prepare for the test?
No preparation is needed; just provide a blood sample as instructed.
What if the transplant is rejected?
If rejection occurs, symptoms like fever or rash may appear; consult a doctor for diagnosis using tests like CBC or biopsy.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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