Heparin Induced Thrombocytopenia (HIT) / Anti Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test
Short Name: PF4-H IgG Quantitative Test
Also known as: HIT Test, PF4-H Antibody Test, Anti-PF4-Heparin IgG Test
Heparin Induced Thrombocytopenia (HIT) / Anti Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test test available at DNA Labs India for ₹16,000. Uses Chemiluminescent Immunoassay (CLIA) on Whole blood samples. Results in Reports available same day if sample received by 11 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To quantitatively measure levels of IgG antibodies against Platelet Factor 4-Heparin complex in the blood, aiding in the diagnosis and management of Heparin Induced Thrombocytopenia (HIT).
- Test Code
- 703
- Price
- ₹16,000
- Sample Type
- Whole blood
- Result Time
- Reports available same day if sample received by 11 am.
- Fasting Required
- Yes (8 hours)
- Method
- Chemiluminescent Immunoassay (CLIA)
Sample Collection
Overnight fasting is preferred. Ensure a duly filled Coagulation Requisition Form (Form 15) is available.
Method: Venipuncture
Laboratory Analysis
Blood sample collected via venipuncture into a 3 mL Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion.
Report Delivery
Transport sample to the lab within 4 hours. If delayed, prepare platelet-poor plasma (PPP) within 1 hour and freeze immediately.
Timeline: Reports available same day if sample received by 11 am.
Patient Instructions
About This Test
Who Should Get This Test
To quantitatively measure levels of IgG antibodies against Platelet Factor 4-Heparin complex in the blood, aiding in the diagnosis and management of Heparin Induced Thrombocytopenia (HIT).
How to Prepare
- Use a Blue Top (Sodium Citrate) tube for collection
- Collect 3 mL of whole blood
- Mix sample by gentle inversion 5-10 times
- Transport to laboratory within 4 hours at room temperature
- If transport is delayed, centrifuge to prepare PPP and freeze immediately
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Early detection of HIT through quantitative IgG testing is critical for preventing life-threatening thrombosis. This test guides immediate clinical intervention."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Clotted or hemolyzed samples
- Improperly labeled or insufficient volume samples
- Samples not stored or transported as per instructions
Understanding Your Results
Consult a doctor immediately if you experience symptoms such as skin rash, shortness of breath, chest pain, or swelling while on heparin therapy, or if test results are positive.
Limitations
- ⚠Results must be interpreted in conjunction with clinical symptoms and platelet counts
- ⚠May not detect all forms of HIT antibodies (e.g., IgA or IgM subtypes)
- ⚠False positives can occur in certain autoimmune conditions
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or excessive bleeding
Interfering Factors
- ●Recent heparin therapy (within the past 2 weeks)
- ●Sample hemolysis or improper handling
- ●Interfering substances in the blood such as lipemia or icterus
Compare With Similar Tests
| Test | Heparin Induced Thrombocytopenia (HIT) / Anti Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test | Platelet Count Test | D-Dimer Test |
|---|---|---|---|
| Comparison | Heparin Induced Thrombocytopenia (HIT) / Anti Platelet Factor 4-Heparin (PF4-H) IgG Quantitative Test | Measures platelet numbers; used alongside HIT test to assess thrombocytopenia. | Detects fibrin degradation products; helps evaluate thrombosis risk. |
Frequently Asked Questions
What is Heparin Induced Thrombocytopenia (HIT)?
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