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HLA - B7 (B*07) Test

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HLA - B7 (B*07) Test

Short Name: HLA-B7 (B*07)

Also known as: Human Leukocyte Antigen B7, HLA Class I B7, HLA-B*07 Allele

HLA - B7 (B*07) Test test available at DNA Labs India for ₹6,000. Uses Reverse SSOP - Luminex on Whole blood samples. Results in 10-12 days after sample receipt.. Free home collection in 300+ cities across India.

Molecular HLA Typing🏠 Home Collection

✍️ Written By

Overview

The HLA-B7 (B*07) test detects the HLA-B*07 allele as a disease association marker. It is used in the evaluation of seronegative spondyloarthropathy, juvenile spondyloarthropathy and undifferentiated spondyloarthropathy, particularly in individuals who are HLA-B27 negative.

Test Code
3477
Price
₹6,000
Sample Type
Whole blood
Result Time
10-12 days after sample receipt.
Fasting Required
No
Method
Reverse SSOP - Luminex
Step 1

Sample Collection

No special preparation or fasting is required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is collected by venipuncture into an EDTA or ACD tube.

Step 3

Report Delivery

Apply pressure to the puncture site. You can resume normal activities.

Timeline: 10-12 days after sample receipt.

Patient Instructions

1
Before the Test:No special preparation or fasting is required.
2
During the Test:A blood sample is collected by venipuncture into an EDTA or ACD tube.
3
After the Test:Apply pressure to the puncture site. You can resume normal activities.

About This Test

Who Should Get This Test

The HLA-B7 (B*07) test detects the HLA-B*07 allele as a disease association marker. It is used in the evaluation of seronegative spondyloarthropathy, juvenile spondyloarthropathy and undifferentiated spondyloarthropathy, particularly in individuals who are HLA-B27 negative.

How to Prepare

  • Collect 4 mL (3 mL min.) whole blood in Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in Yellow Top (ACD) tube.
  • Mix gently by inversion after collection.
  • Ship refrigerated. Do not freeze.

Doctor's Notes

"HLA-B7 should be interpreted as a disease association marker and not as a standalone diagnostic test. A positive result supports clinical evaluation but must be correlated with symptoms and other rheumatology findings."

Test Parameters & Specifications

Sample TypeWhole blood
Sample Volume4 mL (3 mL min.) whole blood in Lavender Top (EDTA) OR 6 mL (3 mL min.) whole blood in Yellow Top (ACD)
ContainerLavender Top (EDTA) tube or Yellow Top (ACD) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerated
Frozen
Sample Rejection Criteria:
  • Frozen sample
  • Clotted sample
  • Severely haemolysed sample
  • Inadequate volume or incorrect tube

Understanding Your Results

HLA-B7 is reported qualitatively as Detected or Not Detected. This test is a disease association marker and does not diagnose any condition on its own.
📊

HLA-B7 (B*07) Detected

The HLA-B*07 allele is present. It may be associated with increased risk of certain autoimmune diseases and may support diagnosis of seronegative, juvenile or undifferentiated spondyloarthropathy, especially when HLA-B27 is negative. Clinical correlation is required.

📊

HLA-B7 (B*07) Not Detected

The HLA-B*07 allele was not identified in the sample tested. This reduces but does not fully exclude risk of related disorders.

⚠️ When to Consult a Doctor:

Consult a rheumatologist if you have persistent inflammatory back pain, joint swelling, skin rash or neurological symptoms, or if your HLA-B7 result is positive.

Limitations

  • ⚠Qualitative test only; it does not quantify disease risk.
  • ⚠A positive result does not confirm a specific disease.
  • ⚠A negative result does not exclude all autoimmune or spondyloarthropathy risk.
  • ⚠Test results should be interpreted with clinical evaluation and other relevant tests.

Risks & Considerations

  • ●Mild pain or bruising at the needle site
  • ●Light-headedness
  • ●Local bleeding

Interfering Factors

  • ●Incorrect sample tube
  • ●Frozen sample transport
  • ●Haemolysed sample
  • ●Clotted sample

Compare With Similar Tests

TestHLA - B7 (B*07) Test
ComparisonHLA - B7 (B*07) Test

Frequently Asked Questions

What is HLA-B7?
HLA-B7 (B*07) is a human leukocyte antigen on white blood cells that helps the immune system recognise foreign substances.
Why is HLA-B7 test done?
It is done to detect HLA-B7 as a disease association marker in seronegative, juvenile and undifferentiated spondyloarthropathy, especially when HLA-B27 is negative.
Which diseases are associated with HLA-B7?
HLA-B7 has been associated with multiple sclerosis, rheumatoid arthritis, psoriasis and spondyloarthropathy, but presence does not mean disease will develop.
Does a positive HLA-B7 result mean disease is present?
No. A positive result only indicates the HLA-B*07 allele is present. It may indicate increased risk and should be interpreted with symptoms and clinical evaluation.
What sample is required for HLA-B7 testing?
4 mL whole blood in Lavender Top (EDTA) or 6 mL in Yellow Top (ACD) tube, shipped refrigerated.
Is fasting required for HLA-B7 test?
No fasting or special preparation is required.
What is the HLA-B7 (B*07) test cost in India?
The test cost is Rs 6000 at DNA Labs India. It may vary by location and laboratory.
What is the turnaround time for HLA-B7 test?
Reports are usually available in 10-12 days.
Which laboratory method is used for HLA-B7 testing?
The test uses Reverse SSOP - Luminex, a molecular HLA typing method.
Is home sample collection available for HLA-B7 test?
Yes, DNA Labs India offers free home sample collection for online bookings across major Indian cities.
What does a Not Detected HLA-B7 result mean?
Not Detected means the HLA-B*07 allele was not identified in the sample. It reduces but does not eliminate all related disease risk.
Can HLA-B7 replace HLA-B27 testing?
No. HLA-B7 complements HLA-B27 testing. HLA-B7 may be positive in some cases of spondyloarthropathy when HLA-B27 is negative.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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