HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test
Short Name: HLA Sensitized Recipient Panel 3
Also known as: HLA Sensitized Recipient Panel 3, Pre-Transplant HLA Antibody Panel 3, HLA Pre-Transplant Workup Panel 3
HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test test available at DNA Labs India for ₹23,049. Uses Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology on Whole Blood samples. Results in Reports are typically available within 10-12 days after sample receipt.. Free home collection in 300+ cities across India.
Overview
Pre-Kidney transplantation workup of recipient to: assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess HLA matching between recipient and donor; evaluate the level of sensitization of recipient to donor; assess allo-immunization status of the recipient.
- Test Code
- 3478
- Price
- ₹23,049
- Sample Type
- Whole Blood
- Result Time
- Reports are typically available within 10-12 days after sample receipt.
- Fasting Required
- No
- Method
- Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology
Sample Collection
Doctor's prescription on the letterhead with one photograph each of recipient and donor duly stamped and Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Method: Venipuncture
Laboratory Analysis
A tourniquet is applied and whole blood is collected by venipuncture into the required ACD and EDTA tubes.
Report Delivery
Ship sample refrigerated. DO NOT FREEZE.
Timeline: Reports are typically available within 10-12 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
Pre-Kidney transplantation workup of recipient to: assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess HLA matching between recipient and donor; evaluate the level of sensitization of recipient to donor; assess allo-immunization status of the recipient.
How to Prepare
- Ensure mandatory documents are available before sample collection
- Collect sample in 2 Yellow Top (ACD) tubes and 1 Lavender Top (EDTA) tube
- Refrigerate sample and transport to the laboratory promptly
- Do not freeze the sample
Doctor's Notes
"HLA sensitization is a major barrier to successful renal transplantation. This panel helps quantify and characterize anti-HLA antibodies in sensitized recipients, guiding donor selection and desensitization decisions."
Test Parameters & Specifications
Sample Stability
- Hemolysed sample
- Clotted sample
- Insufficient volume
- Missing consent form or prescription
Understanding Your Results
Negative CDC crossmatch and no HLA antibodies
Low immunological risk for the tested donor
Positive HLA antibody identification
Recipient is sensitized; donor-specific antibodies should be evaluated
Positive DTT-treated CDC crossmatch
High risk of antibody-mediated rejection; transplant may require desensitization or alternative donor
Consult a transplant nephrologist or immunologist if the panel shows HLA antibodies, positive crossmatch, or donor-specific antibodies.
Limitations
- ⚠Low-resolution HLA DNA typing may not resolve all allele-level differences
- ⚠Luminex antibody identification depends on panel composition and may not detect rare alleles
- ⚠Clinical correlation with transplant history and crossmatch results is required
Risks & Considerations
- ●Mild pain or bruising at the venipuncture site
- ●Lightheadedness
- ●Rare infection at puncture site
Interfering Factors
- ●Autoantibodies may produce false-positive results if DTT treatment is not applied
- ●Recent blood transfusion may transiently affect antibody detection
- ●Immunosuppressive or antibody-depleting therapies may alter antibody levels
Compare With Similar Tests
| Test | HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test | ||
|---|---|---|---|
| Comparison | HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test | Comprehensive antibody identification, HLA DNA typing, and DTT-treated crossmatch | Mainly detects donor-recipient compatibility without detailed antibody identification |
Frequently Asked Questions
What is the HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test?
Why is this test important before kidney transplantation?
What is the cost of the HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test in India?
What sample type is required?
Is fasting required?
What is the turnaround time?
What testing methods are used?
What does a positive HLA antibody result mean?
What documents are mandatory for this test?
Can I book this test online with home collection?
Who should undergo this test?
What are the risks of this blood test?
Related Tests
HLA - Panel Reactive IgG Antibodies (PRA) Class II Quantitative Test
₹15,000HLA - ABC (Class 1) Typing Test
₹12,051HLA - DR (Class II) Typing Test
₹8,658HLA - Panel Reactive IgG Antibodies (PRA) Screen Test
₹8,500HLA DSA (Donor Specific IgG Antibodies) Class I & II Test
₹13,000HLA Typing Test for Donor and Recipient
₹16,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.