HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test
HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test test available at DNA Labs India for ₹41,301. Uses Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology on Whole blood and serum samples. Results in 10-12 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
This test is designed for pre-kidney transplantation workup of recipients to assess a sensitized recipient with a history of multiple blood transfusions, pregnancies, or re-transplants; evaluate HLA matching between recipient and donor; determine the level of sensitization of the recipient to the donor; and assess allo-immunization status. It includes HLA DNA typing for kidney or liver transplant using PCR low-resolution Luminex, HLA T and B cell lymphocyte crossmatch against potential donors, quantitative measurement of HLA Panel Reactive IgG antibodies Class I and II via Luminex, and detection of donor-specific IgG antibodies Class I and II.
- Test Code
- 818
- Price
- ₹41,301
- Sample Type
- Whole blood and serum
- Result Time
- 10-12 days
- Fasting Required
- No
- Method
- Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology
Sample Collection
Collect specimen preferably 48 hours after dialysis. Doctor's prescription on the letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure is followed to collect blood samples from the recipient.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Keep the site clean and dry.
Timeline: 10-12 days
Patient Instructions
About This Test
Who Should Get This Test
This test is designed for pre-kidney transplantation workup of recipients to assess a sensitized recipient with a history of multiple blood transfusions, pregnancies, or re-transplants; evaluate HLA matching between recipient and donor; determine the level of sensitization of the recipient to the donor; and assess allo-immunization status. It includes HLA DNA typing for kidney or liver transplant using PCR low-resolution Luminex, HLA T and B cell lymphocyte crossmatch against potential donors, quantitative measurement of HLA Panel Reactive IgG antibodies Class I and II via Luminex, and detection of donor-specific IgG antibodies Class I and II.
How to Prepare
- Collect specimens preferably 48 hours after dialysis
- Ensure doctor's prescription on letterhead with photographs of recipient and donor is provided
- Obtain signed consent form for HLA Typing for Solid organ transplant (Form 33)
- Use specified sample tubes: Yellow Top (ACD), SST, and Lavender top (EDTA)
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Missing doctor's prescription or consent form
- Insufficient sample volume
- Improper sample collection or storage
Understanding Your Results
Negative crossmatch and low PRA
Lower risk of rejection; suitable for transplant evaluation
Positive crossmatch or high PRA
Higher sensitization; may require desensitization protocols or alternative donors
Donor-specific antibodies detected
Increased risk of antibody-mediated rejection; further consultation needed
Consult a transplant specialist or nephrologist if test results indicate sensitization, positive crossmatch, or the presence of donor-specific antibodies to discuss management options.
Limitations
- ⚠Results may vary based on laboratory techniques and sample quality
- ⚠Does not guarantee transplant success; clinical correlation is required
Risks & Considerations
- ●Minor bruising or discomfort at the puncture site
- ●Rare risk of infection or hematoma
Interfering Factors
- ●Recent blood transfusions
- ●Immunosuppressive therapy
- ●Viral infections
Compare With Similar Tests
| Test | HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test | HLA Typing Test | Crossmatch Test | PRA Test |
|---|---|---|---|---|
| Comparison | HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test |
Frequently Asked Questions
What is the HLA Pre-Transplant Workup Sensitized Recipient Panel 3 Test?
Why is this test important for transplant recipients?
What is the cost of this test?
Is home sample collection available?
How should I prepare for the test?
What documents are required for the test?
How long does it take to get results?
What does a positive result mean?
Are there any risks associated with the test?
Can this test be used for liver transplants?
What techniques are used in this test?
How does this test differ from a standard HLA typing test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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