HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test
Short Name: HLA Pre-Transplant Workup Sensitized Recipient Panel 4
Also known as: HLA Pre-Transplant Workup Panel 4, Sensitized Recipient HLA Panel 4, HLA Transplant Workup Sensitized Recipient Panel
HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test test available at DNA Labs India for ₹68,679. Uses Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry, Sequence based Typing (SBT) on Whole blood and serum samples. Results in Reports are typically available within 10-12 days.. Free home collection in 300+ cities across India.
Overview
Pre-kidney transplantation workup of recipient to: assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess the HLA match/mismatch between recipient and donor at high resolution (allele level); antibody screening for allo-immunization status of the recipient; evaluate the level of sensitization of recipient to donor by antibody identification at allele specificity level and identify specificities of all antibodies present.
- Test Code
- 3484
- Price
- ₹68,679
- Sample Type
- Whole blood and serum
- Result Time
- Reports are typically available within 10-12 days.
- Fasting Required
- No
- Method
- Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry, Sequence based Typing (SBT)
Sample Collection
Schedule collection preferably 48 hours after dialysis. Bring a doctor's prescription on letterhead with one photograph each of recipient and donor duly stamped, and a signed consent Form 33 for HLA typing for solid organ transplant.
Method: Venipuncture
Laboratory Analysis
A phlebotomist will collect multiple blood tubes as follows: 6 mL whole blood in Yellow Top (ACD), 9 mL serum from 3 SSTs, 4 mL whole blood in Lavender Top (EDTA), and 4 mL whole blood in Green Top (Sodium Heparin).
Report Delivery
The specimen should be shipped at 18–22°C. Do not refrigerate or freeze. Reports will be shared via online portal, email, or WhatsApp.
Timeline: Reports are typically available within 10-12 days.
Patient Instructions
About This Test
Who Should Get This Test
Pre-kidney transplantation workup of recipient to: assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess the HLA match/mismatch between recipient and donor at high resolution (allele level); antibody screening for allo-immunization status of the recipient; evaluate the level of sensitization of recipient to donor by antibody identification at allele specificity level and identify specificities of all antibodies present.
How to Prepare
- Collect 6 mL whole blood in 1 Yellow Top (ACD) tube
- Collect 9 mL serum from 3 SST tubes
- Collect 4 mL whole blood in 1 Lavender Top (EDTA) tube
- Collect 4 mL whole blood in 1 Green Top (Sodium Heparin) tube
- Collect specimen preferably 48 hours after dialysis
- Ship at 18–22°C; do not refrigerate or freeze
- Doctor's prescription with photographs and signed Form 33 consent are mandatory
Doctor's Notes
"For sensitized recipients with a history of blood transfusions, pregnancy, or previous transplant, this panel helps identify preformed anti-HLA antibodies and donor-specific responses. It is a critical step before transplantation to reduce rejection risk."
Test Parameters & Specifications
Sample Stability
- Missing doctor's prescription on letterhead with recipient and donor photographs
- Missing signed consent Form 33 for HLA typing for solid organ transplant
- Inadequate sample volume
- Refrigerated or frozen specimen
Understanding Your Results
Consult a transplant nephrologist or transplant physician if the crossmatch is positive, donor-specific antibodies are identified, or if you have symptoms such as fever, decreased urine output, abdominal pain, or swelling.
Limitations
- ⚠A negative crossmatch does not completely exclude all immune risk.
- ⚠Final transplant suitability requires clinical correlation including biopsy and transplant physician assessment.
- ⚠Reference ranges and thresholds may vary by laboratory and testing platform.
Risks & Considerations
- ●Mild pain or bruising at the venipuncture site
- ●Standard low-risk blood draw
Interfering Factors
- ●Specimen should be collected preferably 48 hours after dialysis
- ●Specimen must not be refrigerated or frozen before testing
Frequently Asked Questions
What is the HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test?
Why is this test needed?
What does the panel include?
What sample type is required?
Is fasting required before the test?
What is the cost of the HLA Pre-Transplant Workup Sensitized Recipient Panel 4 Test?
How long does it take to get reports?
Is a doctor's prescription mandatory?
Does DNA Labs India provide home sample collection for this test?
What are the symptoms of organ rejection?
How should the specimen be transported?
What does a positive crossmatch mean?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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