HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test
Short Name: HLA Pre-Transplant Workup Sensitized Recipient Panel 5
Also known as: HLA Pre-Transplant Workup, Sensitized Recipient Panel 5, Pre-Kidney Transplant HLA Workup
HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test test available at DNA Labs India for ₹25,155. Uses Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry on DONOR: 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube AND 4 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Doctor's prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory. samples. Results in 10-12 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 3, 2026
Overview
Pre-kidney transplantation workup of recipient to assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess HLA match/mismatch between recipient and donor at antigen level; detect presence and strength of DSA by antibody identification; monitor effectiveness of desensitization protocols.
- Test Code
- 3487
- Price
- ₹25,155
- Sample Type
- DONOR: 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube AND 4 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube. Ship at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Doctor's prescription on the letter head with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid organ transplant (Form 33) is mandatory.
- Result Time
- 10-12 days
- Fasting Required
- No
- Method
- Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry
Sample Collection
A doctor's prescription on letterhead with one photograph each of recipient and donor duly stamped and Consent Form for HLA Typing for Solid Organ Transplant (Form 33) is mandatory. Keep the samples at room temperature (18-22°C); do not refrigerate or freeze.
Method: Venipuncture
Laboratory Analysis
Collect 4 mL whole blood in an EDTA lavender top tube and 4 mL whole blood in a sodium heparin green top tube from donor and recipient as applicable. Mix gently by inversion; do not shake.
Report Delivery
Ship immediately at 18-22°C. Do not refrigerate or freeze. Ensure the requisition form, consent, photographs, and sample labels are complete.
Timeline: 10-12 days
Patient Instructions
About This Test
Who Should Get This Test
Pre-kidney transplantation workup of recipient to assess a sensitized recipient with history of multiple blood transfusions, pregnancies and re-transplants; assess HLA match/mismatch between recipient and donor at antigen level; detect presence and strength of DSA by antibody identification; monitor effectiveness of desensitization protocols.
How to Prepare
- Carry the doctor's prescription on letterhead with one photograph each of recipient and donor duly stamped
- Carry the signed Consent form for HLA Typing for Solid Organ Transplant (Form 33)
- No fasting is required for this test
- Samples must be kept at room temperature and must not be refrigerated or frozen
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"This panel is indicated for sensitized kidney transplant recipients. Ensure the mandatory Form 33 consent and photographs are submitted with fresh whole blood samples; sample integrity is critical for accurate DSA and flow cytometry results."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Refrigerated or frozen samples
- Samples received beyond 24 hours at room temperature
- Missing mandatory consent or photographs
- Improperly labelled tubes
Understanding Your Results
Low-resolution HLA typing
Used to determine antigen-level match/mismatch between donor and recipient.
DSA negative
Suggests no detectable donor-specific antibody; lower immunologic risk.
DSA positive
Indicates presence of donor-specific antibodies; further assessment for strength and clinical risk is needed.
High MFI DSA
May indicate need for desensitization or modification of transplant plan.
If the report indicates DSA positivity or significant HLA mismatches, consult your nephrologist or transplant team before proceeding with transplantation.
Limitations
- ⚠Low-resolution HLA typing may not resolve allele-level mismatches
- ⚠DSA strength requires correlation with crossmatch and clinical status
- ⚠This panel does not replace clinical assessment by the transplant team
- ⚠Interpretation should consider desensitization protocol status
Risks & Considerations
- ●Mild pain or bruising at the blood collection site
- ●No major risks associated with routine venipuncture
Interfering Factors
- ●Refrigerated or frozen samples
- ●Hemolysed or clotted blood samples
- ●Incomplete or improperly labelled samples
- ●Missing Form 33 consent or photographs
- ●Delayed transport beyond 24 hours at room temperature
Compare With Similar Tests
| Test | HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test | |||
|---|---|---|---|---|
| Comparison | HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test |
Frequently Asked Questions
What is the HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test?
Why is this test performed?
What sample is required for this test?
Is fasting required for the HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test?
What documents are mandatory for this test?
How much does the HLA Pre-Transplant Workup Sensitized Recipient Panel 5 Test cost in India?
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Why must samples not be refrigerated or frozen?
Does DNA Labs India offer home sample collection for this test?
What does a positive donor-specific antibody DSA result mean?
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