HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test
Short Name: DSA-SAB Class I Test
Also known as: HLA Class I Antibody Test, DSA-SAB Class I, HLA Single Antigen Bead Assay
HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test test available at DNA Labs India for ₹28,000. Uses Luminex X-Map Technology on Serum samples. Results in Reports are available in 10-12 days.. Free home collection in 300+ cities across India.
Overview
The purpose of the HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test is to detect the presence and specificity of IgG antibodies against HLA Class I antigens in patients' serum. This is critical for evaluating immunological risk in organ transplantation, identifying donor-specific antibodies that may cause hyperacute or chronic rejection, and informing decisions on organ allocation and immunosuppressive regimens. It is also used in post-transplant monitoring to detect antibodies that may indicate rejection or guide treatment adjustments.
- Test Code
- 824
- Price
- ₹28,000
- Sample Type
- Serum
- Result Time
- Reports are available in 10-12 days.
- Fasting Required
- No
- Method
- Luminex X-Map Technology
Sample Collection
Provide a brief clinical history, including transplant details, medications, and any history of sensitization.
Method: Venipuncture
Laboratory Analysis
A standard venipuncture procedure is performed to collect 2 mL of blood into an SST tube.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. The sample is shipped refrigerated or frozen.
Timeline: Reports are available in 10-12 days.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test is to detect the presence and specificity of IgG antibodies against HLA Class I antigens in patients' serum. This is critical for evaluating immunological risk in organ transplantation, identifying donor-specific antibodies that may cause hyperacute or chronic rejection, and informing decisions on organ allocation and immunosuppressive regimens. It is also used in post-transplant monitoring to detect antibodies that may indicate rejection or guide treatment adjustments.
How to Prepare
- Collect 2 mL serum from 1 SST
- Ship refrigerated or frozen
- Include brief clinical history with the sample
- Ensure proper labeling and documentation
Doctor's Notes
"This test is crucial for pre- and post-transplant evaluation to detect donor-specific antibodies, helping prevent organ rejection and guide immunosuppressive therapy."
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or contaminated samples
- Improper storage or delayed shipment
- Missing clinical history or consent
Understanding Your Results
Consult a doctor if antibodies are detected, especially before or after transplantation, or if experiencing symptoms of rejection such as decreased organ function, fever, or swelling.
Limitations
- ⚠May not detect all antibody subclasses or low-affinity antibodies
- ⚠Results are interpreted in clinical context; false positives can occur
- ⚠Does not replace functional assays like crossmatch testing
- ⚠Limited to IgG antibodies; IgM or other classes are not detected
- ⚠Cost may be a barrier for some patients
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or fainting
- ●No significant long-term risks associated with the test itself
Interfering Factors
- ●Hemolyzed or lipemic serum samples
- ●Recent blood transfusions or plasma exchanges
- ●Use of immunosuppressive medications
- ●Presence of other non-HLA antibodies
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test | HLA Class II Antibody Test | Panel Reactive Antibody (PRA) Test | Crossmatch Test | Luminex-Based Mixed Antigen Bead Assay |
|---|---|---|---|---|---|
| Comparison | HLA Single Antigen Bead Assay for Class I IgG Antibodies DSA-SAB Class I Test |
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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