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HLA Single Antigen Bead Assay for Class II IgG Antibodies DSA-SAB Class II Test

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HLA Single Antigen Bead Assay for Class II IgG Antibodies DSA-SAB Class II Test

Short Name: DSA-SAB Class II Test

Also known as: DSA-SAB Class II Test, HLA Class II Antibody Test

HLA Single Antigen Bead Assay for Class II IgG Antibodies DSA-SAB Class II Test test available at DNA Labs India for ₹26,000. Uses Luminex X-Map technology on Serum samples. Results in Reports available in 10-12 days.. Free home collection in 300+ cities across India.

Immunology Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect donor-specific HLA Class II IgG antibodies in transplant recipients, aiding in the diagnosis of antibody-mediated rejection, risk stratification, and treatment planning for autoimmune conditions and transplant management.

Test Code
826
Price
₹26,000
Sample Type
Serum
Result Time
Reports available in 10-12 days.
Fasting Required
No
Method
Luminex X-Map technology
Step 1

Sample Collection

No special preparation required. Provide a brief clinical history as instructed.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in the arm using standard venipuncture.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities.

Timeline: Reports available in 10-12 days.

Patient Instructions

1
Before the Test:No fasting required. Inform your doctor about any medications or health conditions.
2
During the Test:A blood sample is collected from the arm.
3
After the Test:You can resume normal activities immediately. Minor bruising may occur at the puncture site.

About This Test

Who Should Get This Test

To detect donor-specific HLA Class II IgG antibodies in transplant recipients, aiding in the diagnosis of antibody-mediated rejection, risk stratification, and treatment planning for autoimmune conditions and transplant management.

How to Prepare

  • Use SST (Serum Separator Tube)
  • Ship sample refrigerated or frozen
  • Include brief clinical history with sample

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This assay is critical for assessing donor-specific antibodies in kidney transplant recipients, helping to predict and manage antibody-mediated rejection."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature6 hours
Refrigerated72 hours
Frozen1 week
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improper container or labeling

Understanding Your Results

Results indicate the presence or absence of HLA Class II IgG antibodies. Positive results suggest sensitization and may correlate with transplant rejection risk.
Positive result: Antibodies detected, indicating sensitization; consult transplant specialist
Negative result: No antibodies detected, lower rejection risk
Quantitative MFI values may be reported for antibody strength
Results should be interpreted alongside clinical history and other tests
⚠️ When to Consult a Doctor:

If test is positive, or if experiencing symptoms like fever, fatigue, reduced urine output, or signs of transplant rejection post-transplantation.

Limitations

  • ⚠May not detect all antibody specificities
  • ⚠Results require clinical correlation
  • ⚠Cross-reactivity possible with other HLA antigens

Risks & Considerations

  • ●Minor bruising or pain at puncture site
  • ●Rare risk of infection or hematoma

Interfering Factors

  • ●Hemolyzed or lipemic samples
  • ●Sample contamination
  • ●Improper storage conditions

Frequently Asked Questions

What is the HLA Single Antigen Bead Assay for Class II IgG Antibodies?
It is a blood test that detects donor-specific HLA Class II antibodies, important for transplant evaluation.
Why is this test recommended?
To assess sensitization risk before transplants and monitor rejection post-transplant.
How is the test performed?
A blood sample is analyzed using Luminex technology to identify specific HLA antibodies.
What does a positive result mean?
It indicates presence of HLA antibodies, suggesting increased risk of antibody-mediated rejection.
How long does it take to get results?
Reports are typically available in 10-12 days.
Is the test painful?
It involves a standard blood draw, so discomfort is minimal.
Are there any risks?
Risks are minor, such as bruising at the puncture site.
How should I prepare for the test?
No fasting needed, but provide clinical history as instructed.
What is the cost of the test?
The cost is INR 26,000 in India.
Is home collection available?
Yes, free home collection is offered across India.
Can I eat before the test?
Yes, fasting is not required.
How accurate is the test?
The assay has high sensitivity and specificity using advanced technology.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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