Protein S Antigen Free Test
Short Name: Protein S Free Antigen Test
Also known as: Protein S Functional Activity Test, Protein S Free Antigen Test
Protein S Antigen Free Test test available at DNA Labs India for ₹4,500. Uses Electromechanical Clot Detection on Whole Blood samples. Results in Next day after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Gottipati Vemkateswarlu
Consultant Hematologist · Reg: AMC4946
Last reviewed: September 7, 2026
Overview
This assay is used as an adjunct to initial testing based on the results of Protein S antigen assay. It helps in evaluating patients with history of venous thromboembolism and diagnosing Congenital / Acquired Protein S deficiency.
- Test Code
- 4556
- Price
- ₹4,500
- Sample Type
- Whole Blood
- Result Time
- Next day after sample receipt.
- Fasting Required
- Yes (12 hours)
- Method
- Electromechanical Clot Detection
Sample Collection
Overnight fasting is preferred. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Method: Venipuncture
Laboratory Analysis
Blood sample collected by trained technician via venipuncture in a sodium citrate tube.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Sample processed as per instructions for stability.
Timeline: Next day after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
This assay is used as an adjunct to initial testing based on the results of Protein S antigen assay. It helps in evaluating patients with history of venous thromboembolism and diagnosing Congenital / Acquired Protein S deficiency.
How to Prepare
- 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube.
- Mix thoroughly by inversion.
- Transport to Lab within 4 hours.
- If not possible, prepare PPP within 1 hour: Centrifuge at 3600 rpm for 15 min, transfer supernatant, centrifuge again, transfer to vial, freeze immediately.
- Ship frozen. Do not thaw.
Doctor's Notes
Reviewed by Dr Gottipati Vemkateswarlu — MBBS, MD (Haematology) · Reg. No. AMC4946
"This test is crucial for patients with a history of blood clots to assess Protein S levels and guide treatment for thrombotic disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Incorrect tube type
- Insufficient sample volume
- Sample not processed correctly
Understanding Your Results
Protein S activity is within normal limits.
Range: 60-150%
Level: Normal
Indicates Protein S deficiency, which may be congenital or acquired.
Range: <60%
Level: Low
Rarely clinically significant, but may be seen in certain conditions.
Range: >150%
Level: High
If you have a history of blood clots, recurrent miscarriages, or family history of thrombophilia, consult a haematologist for evaluation.
Limitations
- ⚠This test measures functional activity and may not detect all types of Protein S deficiency.
- ⚠Results should be interpreted in conjunction with clinical history and other coagulation tests.
Risks & Considerations
- ●Bruising at puncture site
- ●Infection (rare)
- ●Fainting
Interfering Factors
- ●Heparin therapy
- ●Oral anticoagulant therapy
- ●Liver disease
- ●Vitamin K deficiency
- ●Pregnancy
Compare With Similar Tests
| Test | Protein S Antigen Free Test | Protein S Antigen Total | Protein C Activity | Antithrombin III |
|---|---|---|---|---|
| Comparison | Protein S Antigen Free Test |
Frequently Asked Questions
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