SH2D1A Gene Lymphoproliferative syndrome, X-linked type 1 NGS Genetic Test
Also known as: Lymphoproliferative syndrome, X-linked type 1, XLP-1
SH2D1A Gene Lymphoproliferative syndrome, X-linked type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose X-linked lymphoproliferative syndrome type 1 (XLP-1) by detecting mutations in the SH2D1A gene using next-generation sequencing technology.
- Test Code
- 5601
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with XLP-1.
Method: Venipuncture for blood sample
Laboratory Analysis
Standard blood collection procedure via venipuncture.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Keep the area clean.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose X-linked lymphoproliferative syndrome type 1 (XLP-1) by detecting mutations in the SH2D1A gene using next-generation sequencing technology.
How to Prepare
- Provide clinical history
- Undergo genetic counseling
- Draw pedigree chart
- Collect blood sample as specified
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
Positive for SH2D1A mutation
Diagnosis of X-linked lymphoproliferative syndrome type 1 confirmed.
Negative for SH2D1A mutation
No mutations detected; clinical correlation recommended.
If you experience symptoms such as recurrent infections, enlarged spleen or liver, or other signs of immune dysfunction, consult a healthcare provider.
Limitations
- ⚠May not detect all types of mutations
- ⚠Requires genetic counseling for interpretation
Frequently Asked Questions
What is X-linked lymphoproliferative syndrome type 1 (XLP-1)?
What causes XLP-1?
What are the symptoms of XLP-1?
How is XLP-1 diagnosed?
What is the SH2D1A Gene NGS Genetic Test?
How is the test performed?
What sample is required for the test?
Is fasting required before the test?
How long does it take to get the results?
What is the cost of the test?
Is the test covered by insurance?
Where can I get the test done?
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